Compile Data Set for Download or QSAR
Report error Found 9 Enz. Inhib. hit(s) with all data for entry = 50006856
TargetHistone deacetylase 6(Human)
Institute of Biotechnology of The Czech Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50398716(CHEMBL2179618 | US9409858, 5g | US9751832, Compoun...)
Affinity DataIC50: 3.80nMAssay Description:Inhibition of human N-terminal tagged human HDAC6 expressed in HEK293T/17 using Ac-Gly-Ala-[Ac-Lys]-AMC as substrate preincubated for 10 mins followe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Institute of Biotechnology of The Czech Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50503977(CHEMBL4465902)
Affinity DataIC50: 8.70nMAssay Description:Inhibition of human N-terminal tagged human HDAC6 expressed in HEK293T/17 using Ac-Gly-Ala-[Ac-Lys]-AMC as substrate preincubated for 10 mins followe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetHistone deacetylase 5(Human)
Institute of Biotechnology of The Czech Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50503977(CHEMBL4465902)
Affinity DataIC50: 300nMAssay Description:Inhibition of human N-terminal tagged human HDAC5 expressed in HEK293T/17 using Boc-[TFA-Lys]-AMC as substrate preincubated for 10 mins followed by s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetHistone deacetylase 9(Human)
Institute of Biotechnology of The Czech Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50503977(CHEMBL4465902)
Affinity DataIC50: 300nMAssay Description:Inhibition of human N-terminal tagged human HDAC9 expressed in HEK293T/17 using Boc-[TFA-Lys]-AMC as substrate preincubated for 10 mins followed by s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetHistone deacetylase 7(Human)
Institute of Biotechnology of The Czech Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50503977(CHEMBL4465902)
Affinity DataIC50: 300nMAssay Description:Inhibition of human N-terminal tagged human HDAC7 expressed in HEK293T/17 using Boc-[TFA-Lys]-AMC as substrate preincubated for 10 mins followed by s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Institute of Biotechnology of The Czech Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50503977(CHEMBL4465902)
Affinity DataIC50: 300nMAssay Description:Inhibition of human N-terminal tagged human HDAC1 expressed in HEK293T/17 using Ac-Gly-Ala-[Ac-Lys]-AMC as substrate preincubated for 10 mins followe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetHistone deacetylase 11(Human)
Institute of Biotechnology of The Czech Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50503977(CHEMBL4465902)
Affinity DataIC50: 300nMAssay Description:Inhibition of human N-terminal tagged human HDAC11 expressed in HEK293T/17 using Boc-[TFA-Lys]-AMC as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
Institute of Biotechnology of The Czech Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50503977(CHEMBL4465902)
Affinity DataIC50: 300nMAssay Description:Inhibition of human N-terminal tagged human HDAC4 expressed in HEK293T/17 using Boc-[TFA-Lys]-AMC as substrate preincubated for 10 mins followed by s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Institute of Biotechnology of The Czech Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50503977(CHEMBL4465902)
Affinity DataIC50: 300nMAssay Description:Inhibition of human N-terminal tagged human HDAC8 expressed in HEK293T/17 using Boc-[TFA-Lys]-AMC as substrate preincubated for 10 mins followed by s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed