Compile Data Set for Download or QSAR
Report error Found 30 Enz. Inhib. hit(s) with all data for entry = 50008871
TargetEstrogen receptor(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50523039(CHEMBL4591338)
Affinity DataIC50: 0.0100nMAssay Description:Induction of ERalpha degradation in human MCF7 cells after 4 hrs by FITC/Hoechst 33342 staining based immunofluorescence imaging analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM368199((S)-2-(4-(2-(3-(fluoromethyl)azetidin-1-yl)ethoxy)...)
Affinity DataIC50: 0.0300nMAssay Description:Induction of ERalpha degradation in human MCF7 cells after 4 hrs by FITC/Hoechst 33342 staining based immunofluorescence imaging analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetEstrogen receptor(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50523049(CHEMBL4441471)
Affinity DataIC50: 0.0300nMAssay Description:Induction of ERalpha degradation in human MCF7 cells after 4 hrs by FITC/Hoechst 33342 staining based immunofluorescence imaging analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50523050(CHEMBL4455953)
Affinity DataIC50: 0.0500nMAssay Description:Induction of ERalpha degradation in human MCF7 cells after 4 hrs by FITC/Hoechst 33342 staining based immunofluorescence imaging analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetEstrogen receptor(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50523040(CHEMBL4463541)
Affinity DataIC50: 0.0700nMAssay Description:Induction of ERalpha degradation in human MCF7 cells after 4 hrs by FITC/Hoechst 33342 staining based immunofluorescence imaging analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50523035(CHEMBL4594150)
Affinity DataIC50: 0.0800nMAssay Description:Induction of ERalpha degradation in human MCF7 cells after 4 hrs by FITC/Hoechst 33342 staining based immunofluorescence imaging analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50523057(CHEMBL4447143)
Affinity DataIC50: 0.170nMAssay Description:Induction of ERalpha degradation in human MCF7 cells after 4 hrs by FITC/Hoechst 33342 staining based immunofluorescence imaging analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50523053(CHEMBL4567402)
Affinity DataIC50: 0.200nMAssay Description:Induction of ERalpha degradation in human MCF7 cells after 4 hrs by FITC/Hoechst 33342 staining based immunofluorescence imaging analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50523054(CHEMBL4476031)
Affinity DataIC50: 0.200nMAssay Description:Induction of ERalpha degradation in human MCF7 cells after 4 hrs by FITC/Hoechst 33342 staining based immunofluorescence imaging analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50523062(CHEMBL4450730)
Affinity DataIC50: 0.280nMAssay Description:Induction of ERalpha degradation in human MCF7 cells after 4 hrs by FITC/Hoechst 33342 staining based immunofluorescence imaging analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50508708(CHEMBL4438260)
Affinity DataIC50: 0.300nMAssay Description:Induction of ERalpha degradation in human MCF7 cells after 4 hrs by FITC/Hoechst 33342 staining based immunofluorescence imaging analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50523041(CHEMBL4588281)
Affinity DataIC50: 0.300nMAssay Description:Induction of ERalpha degradation in human MCF7 cells after 4 hrs by FITC/Hoechst 33342 staining based immunofluorescence imaging analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50523051(CHEMBL4456532)
Affinity DataIC50: 0.420nMAssay Description:Induction of ERalpha degradation in human MCF7 cells after 4 hrs by FITC/Hoechst 33342 staining based immunofluorescence imaging analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50523060(CHEMBL4468700)
Affinity DataIC50: 0.5nMAssay Description:Induction of ERalpha degradation in human MCF7 cells after 4 hrs by FITC/Hoechst 33342 staining based immunofluorescence imaging analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50523042(CHEMBL4552853)
Affinity DataIC50: 0.5nMAssay Description:Induction of ERalpha degradation in human MCF7 cells after 4 hrs by FITC/Hoechst 33342 staining based immunofluorescence imaging analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50523038(CHEMBL4470926)
Affinity DataIC50: 0.5nMAssay Description:Induction of ERalpha degradation in human MCF7 cells after 4 hrs by FITC/Hoechst 33342 staining based immunofluorescence imaging analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50523048(CHEMBL4462970)
Affinity DataIC50: 0.580nMAssay Description:Induction of ERalpha degradation in human MCF7 cells after 4 hrs by FITC/Hoechst 33342 staining based immunofluorescence imaging analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50523059(CHEMBL4586333)
Affinity DataIC50: 1nMAssay Description:Induction of ERalpha degradation in human MCF7 cells after 4 hrs by FITC/Hoechst 33342 staining based immunofluorescence imaging analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50523043(CHEMBL4543969)
Affinity DataIC50: 1.10nMAssay Description:Induction of ERalpha degradation in human MCF7 cells after 4 hrs by FITC/Hoechst 33342 staining based immunofluorescence imaging analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50523052(CHEMBL4531089)
Affinity DataIC50: 2.5nMAssay Description:Induction of ERalpha degradation in human MCF7 cells after 4 hrs by FITC/Hoechst 33342 staining based immunofluorescence imaging analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50523046(CHEMBL4534455)
Affinity DataIC50: 3nMAssay Description:Induction of ERalpha degradation in human MCF7 cells after 4 hrs by FITC/Hoechst 33342 staining based immunofluorescence imaging analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50523058(CHEMBL4460089)
Affinity DataIC50: 5.70nMAssay Description:Induction of ERalpha degradation in human MCF7 cells after 4 hrs by FITC/Hoechst 33342 staining based immunofluorescence imaging analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50523045(CHEMBL4451300)
Affinity DataIC50: 15nMAssay Description:Induction of ERalpha degradation in human MCF7 cells after 4 hrs by FITC/Hoechst 33342 staining based immunofluorescence imaging analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50523047(CHEMBL4437725)
Affinity DataIC50: 27nMAssay Description:Induction of ERalpha degradation in human MCF7 cells after 4 hrs by FITC/Hoechst 33342 staining based immunofluorescence imaging analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50523061(CHEMBL4578130)
Affinity DataIC50: 72nMAssay Description:Induction of ERalpha degradation in human MCF7 cells after 4 hrs by FITC/Hoechst 33342 staining based immunofluorescence imaging analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50523044(CHEMBL4476007)
Affinity DataIC50: 100nMAssay Description:Induction of ERalpha degradation in human MCF7 cells after 4 hrs by FITC/Hoechst 33342 staining based immunofluorescence imaging analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50523055(CHEMBL4482870)
Affinity DataIC50: 100nMAssay Description:Induction of ERalpha degradation in human MCF7 cells after 4 hrs by FITC/Hoechst 33342 staining based immunofluorescence imaging analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50523056(CHEMBL4564477)
Affinity DataIC50: 100nMAssay Description:Induction of ERalpha degradation in human MCF7 cells after 4 hrs by FITC/Hoechst 33342 staining based immunofluorescence imaging analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50523037(CHEMBL4544038)
Affinity DataIC50: 100nMAssay Description:Induction of ERalpha degradation in human MCF7 cells after 4 hrs by FITC/Hoechst 33342 staining based immunofluorescence imaging analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50523036(CHEMBL4543659)
Affinity DataIC50: 100nMAssay Description:Induction of ERalpha degradation in human MCF7 cells after 4 hrs by FITC/Hoechst 33342 staining based immunofluorescence imaging analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed