Compile Data Set for Download or QSAR
Report error Found 67 Enz. Inhib. hit(s) with all data for entry = 50008237
TargetAcetylcholine receptor subunit epsilon(Human)
Wuhan Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50516960(CHEMBL4435544)
Affinity DataIC50: 6nMAssay Description:Inhibition of AChE (unknown origin) after 2 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetCholinesterase(Human)
Wuhan Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50516960(CHEMBL4435544)
Affinity DataIC50: 6nMAssay Description:Inhibition of BuChE (unknown origin) after 2 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetAcetylcholine receptor subunit epsilon(Human)
Wuhan Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50516959(CHEMBL4471876)
Affinity DataIC50: 27nMAssay Description:Inhibition of AChE (unknown origin) after 2 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetCholinesterase(Human)
Wuhan Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50516959(CHEMBL4471876)
Affinity DataIC50: 27nMAssay Description:Inhibition of BuChE (unknown origin) after 2 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetAcetylcholine receptor subunit epsilon(Human)
Wuhan Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50516976(CHEMBL4518438)
Affinity DataIC50: 47nMAssay Description:Inhibition of AChE (unknown origin) by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetCholinesterase(Human)
Wuhan Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50516977(CHEMBL4518992)
Affinity DataIC50: 49nMAssay Description:Inhibition of BuChE (unknown origin) by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetCholinesterase(Human)
Wuhan Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50516975(CHEMBL4514263)
Affinity DataIC50: 49nMAssay Description:Inhibition of BuChE (unknown origin) by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetCholinesterase(Human)
Wuhan Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50516974(CHEMBL4516351)
Affinity DataIC50: 56nMAssay Description:Inhibition of BuChE (unknown origin) by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetAcetylcholine receptor subunit epsilon(Human)
Wuhan Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50516974(CHEMBL4516351)
Affinity DataIC50: 57nMAssay Description:Inhibition of AChE (unknown origin) by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetAcetylcholine receptor subunit epsilon(Human)
Wuhan Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50516977(CHEMBL4518992)
Affinity DataIC50: 58nMAssay Description:Inhibition of AChE (unknown origin) by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetAcetylcholine receptor subunit epsilon(Human)
Wuhan Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50516975(CHEMBL4514263)
Affinity DataIC50: 62nMAssay Description:Inhibition of AChE (unknown origin) by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetCholinesterase(Human)
Wuhan Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50516976(CHEMBL4518438)
Affinity DataIC50: 70nMAssay Description:Inhibition of BuChE (unknown origin) by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetAcetylcholine receptor subunit epsilon(Human)
Wuhan Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50516963(CHEMBL2376519)
Affinity DataIC50: 82nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetAcetylcholine receptor subunit epsilon(Human)
Wuhan Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50516982(CHEMBL4447626)
Affinity DataIC50: 88nMAssay Description:Inhibition of AChE (unknown origin) by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetCholinesterase(Human)
Wuhan Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50516950(CHEMBL4544630)
Affinity DataIC50: 94nMAssay Description:Inhibition of BuChE (unknown origin) by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetAcetylcholine receptor subunit epsilon(Human)
Wuhan Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50516950(CHEMBL4544630)
Affinity DataIC50: 97nMAssay Description:Inhibition of AChE (unknown origin) by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Wuhan Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50516991(CHEMBL4466253)
Affinity DataIC50: 117nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition measured after 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetCholinesterase(Human)
Wuhan Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50516982(CHEMBL4447626)
Affinity DataIC50: 125nMAssay Description:Inhibition of BuChE (unknown origin) by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Wuhan Institute of Technology

Curated by ChEMBL
LigandPNGBDBM167925((1-(2-Chlorobenzyl)-1H-1,2,3-triazol-4-yl)methyl 2...)
Affinity DataIC50: 180nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition measured after 6 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Wuhan Institute of Technology

Curated by ChEMBL
LigandPNGBDBM8961(CHEMBL95 | Cognex | cid_1935 | CHEMBL1337960 | 1,2...)
Affinity DataIC50: 350nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition measured after 6 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetCholinesterase(Human)
Wuhan Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50004000(CHEMBL94 | physostigmine | Antilirium | Eserine | ...)
Affinity DataIC50: 850nMAssay Description:Inhibition of BuChE (unknown origin) using butyrylthiocholine chloride as substrate preincubated for 15 mins followed by substrate addition measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Wuhan Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50516952(CHEMBL4465307)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 3 mins followed by substrate additionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetAcetylcholine receptor subunit epsilon(Human)
Wuhan Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50516970(CHEMBL4456791)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of human AChE using acetylthiocholine iodide as substrate after 10 secs measured at 30 s intervals for two minutes by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetAcetylcholine receptor subunit epsilon(Human)
Wuhan Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50516985(CHEMBL4544034)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetAcetylcholine receptor subunit epsilon(Human)
Wuhan Institute of Technology

Curated by ChEMBL
LigandPNGBDBM10404(galantamine | (1S,12S,14R)-9-methoxy-4-methyl-11-o...)
Affinity DataIC50: 2.66E+3nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetAcetylcholine receptor subunit epsilon(Human)
Wuhan Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50516966(CHEMBL4452517)
Affinity DataIC50: 2.72E+3nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetAcetylcholine receptor subunit epsilon(Human)
Wuhan Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50516965(CHEMBL4458943)
Affinity DataIC50: 3.06E+3nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Wuhan Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50516987(CHEMBL4437630)
Affinity DataIC50: 3.29E+3nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 3 mins followed by substrate additionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Wuhan Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50516957(CHEMBL4520853)
Affinity DataIC50: 3.29E+3nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 3 mins followed by substrate additionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Wuhan Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50516956(CHEMBL4593774)
Affinity DataIC50: 3.29E+3nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 3 mins followed by substrate additionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Wuhan Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50516955(CHEMBL4439610)
Affinity DataIC50: 3.29E+3nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 3 mins followed by substrate additionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Wuhan Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50516984(CHEMBL4476479)
Affinity DataIC50: 3.29E+3nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 3 mins followed by substrate additionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetCholinesterase(Human)
Wuhan Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50516986(CHEMBL4461294)
Affinity DataIC50: 4.52E+3nMAssay Description:Inhibition of BuChE (unknown origin) using butyrylthiocholine chloride as substrate preincubated for 15 mins followed by substrate addition measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetCholinesterase(Human)
Wuhan Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50516951(CHEMBL4527996)
Affinity DataIC50: 4.52E+3nMAssay Description:Inhibition of BuChE (unknown origin) using butyrylthiocholine chloride as substrate preincubated for 15 mins followed by substrate addition measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetCholinesterase(Human)
Wuhan Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50516979(CHEMBL4452614)
Affinity DataIC50: 4.52E+3nMAssay Description:Inhibition of BuChE (unknown origin) using butyrylthiocholine chloride as substrate preincubated for 15 mins followed by substrate addition measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetCholinesterase(Human)
Wuhan Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50516980(CHEMBL4571452)
Affinity DataIC50: 4.52E+3nMAssay Description:Inhibition of BuChE (unknown origin) using butyrylthiocholine chloride as substrate preincubated for 15 mins followed by substrate addition measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetCholinesterase(Human)
Wuhan Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50516981(CHEMBL4532230)
Affinity DataIC50: 4.52E+3nMAssay Description:Inhibition of BuChE (unknown origin) using butyrylthiocholine chloride as substrate preincubated for 15 mins followed by substrate addition measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetCholinesterase(Human)
Wuhan Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50516993(CHEMBL4521999)
Affinity DataIC50: 5.31E+3nMAssay Description:Inhibition of BuChE (unknown origin) using butyrylthiocholine chloride as substrate preincubated for 15 mins followed by substrate addition measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetAcetylcholine receptor subunit epsilon(Human)
Wuhan Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50516964(CHEMBL4573754)
Affinity DataIC50: 6.37E+3nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetAmyloid-beta precursor protein(Human)
Wuhan Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50140172(CHEBI:3962 | CHEMBL140 | Curcumin | US9409845, Tab...)
Affinity DataIC50: 6.39E+3nMAssay Description:Inhibition of amyloid beta (1 to 42) (unknown origin) self aggregationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Wuhan Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50516954(CHEMBL4451075)
Affinity DataIC50: 7.30E+3nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 3 mins followed by substrate additionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetAcetylcholine receptor subunit epsilon(Human)
Wuhan Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50516989(CHEMBL4590975)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetAmyloid-beta precursor protein(Human)
Wuhan Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50516988(CHEMBL4522050)
Affinity DataIC50: 8.07E+3nMAssay Description:Inhibition of amyloid beta (1 to 42) (unknown origin) self aggregationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Wuhan Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50516948(CHEMBL4547910)
Affinity DataIC50: 8.55E+3nMAssay Description:Inhibition of BACE1 (unknown origin) expressed in baculovirus-expression system using Rh-EVNLDAEFK-Quencher substrate after 90 mins by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Wuhan Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50516958(CHEMBL4556299)
Affinity DataIC50: 1.14E+4nMAssay Description:Inhibition of BACE1 (unknown origin) expressed in baculovirus-expression system using Rh-EVNLDAEFK-Quencher substrate after 90 mins by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetAcetylcholine receptor subunit epsilon(Human)
Wuhan Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50516949(CHEMBL4555431)
Affinity DataIC50: 1.23E+4nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Wuhan Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50022775(m-Trimethylammoniumphenyldimethylcarbamate | Prost...)
Affinity DataIC50: 1.63E+4nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition measured after 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetCholinesterase(Human)
Wuhan Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50516961(CHEMBL4471734)
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of BuChE (unknown origin) using butyrylthiocholine iodide as substrate after 15 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetCholinesterase(Horse)
Wuhan Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50516954(CHEMBL4451075)
Affinity DataIC50: 6.86E+4nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine iodide as substrate preincubated for 3 mins followed by substrate additionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Wuhan Institute of Technology

Curated by ChEMBL
LigandPNGBDBM8960(2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2...)
Affinity DataIC50: 7.90E+4nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate after 15 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
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