Compile Data Set for Download or QSAR
Report error Found 21 Enz. Inhib. hit(s) with all data for entry = 50007796
TargetMetabotropic glutamate receptor 3(Rat)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50278662(CHEMBL4172540)
Affinity DataIC50: 245nMAssay Description:Negative allosteric modulation of rat mGlu3R expressed in HEK293 cells co-expressing Galpha15 assessed as decrease in glutamate-induced calcium mobil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 3(Rat)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50512690(CHEMBL4451520)
Affinity DataIC50: 520nMAssay Description:Negative allosteric modulation of rat mGlu3R expressed in HEK cells harboring GIRK assessed as reduction in glutamate-induced thallium fluxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 3(Rat)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50512692(CHEMBL4474204)
Affinity DataIC50: 920nMAssay Description:Negative allosteric modulation of rat mGlu3R expressed in HEK cells harboring GIRK assessed as reduction in glutamate-induced thallium fluxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 3(Rat)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50278662(CHEMBL4172540)
Affinity DataIC50: 1.28E+3nMAssay Description:Negative allosteric modulation of rat mGlu3R expressed in HEK cells harboring GIRK assessed as reduction in glutamate-induced thallium flux preincuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 3(Rat)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50512683(CHEMBL4468538)
Affinity DataIC50: 1.30E+3nMAssay Description:Negative allosteric modulation of rat mGlu3R expressed in HEK cells harboring GIRK assessed as reduction in glutamate-induced thallium fluxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 3(Rat)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50512694(CHEMBL4554871)
Affinity DataIC50: 1.30E+3nMAssay Description:Negative allosteric modulation of rat mGlu3R expressed in HEK cells harboring GIRK assessed as reduction in glutamate-induced thallium fluxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 3(Rat)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50512682(CHEMBL4520808)
Affinity DataIC50: 1.40E+3nMAssay Description:Negative allosteric modulation of rat mGlu3R expressed in HEK cells harboring GIRK assessed as reduction in glutamate-induced thallium fluxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 3(Rat)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50512698(CHEMBL4572957)
Affinity DataIC50: 1.50E+3nMAssay Description:Negative allosteric modulation of rat mGlu3R expressed in HEK cells harboring GIRK assessed as reduction in glutamate-induced thallium fluxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 3(Rat)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50512697(CHEMBL4527797)
Affinity DataIC50: 2.70E+3nMAssay Description:Negative allosteric modulation of rat mGlu3R expressed in HEK cells harboring GIRK assessed as reduction in glutamate-induced thallium fluxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 3(Rat)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50512685(CHEMBL4524912)
Affinity DataIC50: 3.00E+3nMAssay Description:Negative allosteric modulation of rat mGlu3R expressed in HEK cells harboring GIRK assessed as reduction in glutamate-induced thallium fluxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 3(Rat)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50512696(CHEMBL4519557)
Affinity DataIC50: 3.10E+3nMAssay Description:Negative allosteric modulation of rat mGlu3R expressed in HEK cells harboring GIRK assessed as reduction in glutamate-induced thallium fluxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 3(Rat)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50512687(CHEMBL4586828)
Affinity DataIC50: 3.20E+3nMAssay Description:Negative allosteric modulation of rat mGlu3R expressed in HEK cells harboring GIRK assessed as reduction in glutamate-induced thallium fluxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 3(Rat)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50512681(CHEMBL4446121)
Affinity DataIC50: 3.20E+3nMAssay Description:Negative allosteric modulation of rat mGlu3R expressed in HEK cells harboring GIRK assessed as reduction in glutamate-induced thallium fluxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 3(Rat)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50512689(CHEMBL4437442)
Affinity DataIC50: 4.10E+3nMAssay Description:Negative allosteric modulation of rat mGlu3R expressed in HEK cells harboring GIRK assessed as reduction in glutamate-induced thallium fluxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 3(Rat)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50512688(CHEMBL4445711)
Affinity DataIC50: 7.70E+3nMAssay Description:Negative allosteric modulation of rat mGlu3R expressed in HEK cells harboring GIRK assessed as reduction in glutamate-induced thallium fluxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 3(Rat)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50512686(CHEMBL4573287)
Affinity DataIC50: 1.00E+4nMAssay Description:Negative allosteric modulation of rat mGlu3R expressed in HEK cells harboring GIRK assessed as reduction in glutamate-induced thallium fluxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 3(Rat)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50512691(CHEMBL4574649)
Affinity DataIC50: 1.00E+4nMAssay Description:Negative allosteric modulation of rat mGlu3R expressed in HEK cells harboring GIRK assessed as reduction in glutamate-induced thallium fluxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 3(Rat)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50512693(CHEMBL4472852)
Affinity DataIC50: 1.00E+4nMAssay Description:Negative allosteric modulation of rat mGlu3R expressed in HEK cells harboring GIRK assessed as reduction in glutamate-induced thallium fluxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 3(Rat)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50512684(CHEMBL4465627)
Affinity DataIC50: 1.00E+4nMAssay Description:Negative allosteric modulation of rat mGlu3R expressed in HEK cells harboring GIRK assessed as reduction in glutamate-induced thallium fluxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 3(Rat)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50278663(CHEMBL4164660)
Affinity DataIC50: 1.00E+4nMAssay Description:Negative allosteric modulation of rat mGlu3R expressed in HEK cells harboring GIRK assessed as reduction in glutamate-induced thallium fluxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 3(Rat)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50512695(CHEMBL4540170)
Affinity DataIC50: 1.00E+4nMAssay Description:Negative allosteric modulation of rat mGlu3R expressed in HEK cells harboring GIRK assessed as reduction in glutamate-induced thallium fluxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed