Compile Data Set for Download or QSAR
Report error Found 19 Enz. Inhib. hit(s) with all data for entry = 50002476
TargetRenin(Human)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50022582(Diastereomer-5-[2-[2-Benzyl-3-(2-methyl-propane-2-...)
Affinity DataIC50: 0.400nMAssay Description:In vitro inhibition of Human kideny reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50022582(Diastereomer-5-[2-[2-Benzyl-3-(2-methyl-propane-2-...)
Affinity DataIC50: 1nMAssay Description:In vitro inhibition of marmoset plasma reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50022582(Diastereomer-5-[2-[2-Benzyl-3-(2-methyl-propane-2-...)
Affinity DataIC50: 2nMpH: 7.2Assay Description:In vitro inhibition of purified Human kidney renin (250 pg/mL) incubated with angiotensinogen at pH 7.2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50022582(Diastereomer-5-[2-[2-Benzyl-3-(2-methyl-propane-2-...)
Affinity DataIC50: 2nMAssay Description:In vitro inhibition of Human plasma reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50022582(Diastereomer-5-[2-[2-Benzyl-3-(2-methyl-propane-2-...)
Affinity DataIC50: 2nMpH: 7.2Assay Description:In vitro inhibition of purified Human kidney renin (250 pg/mL) incubated with angiotensinogen at pH 7.2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50022586(5-[2-[2-Benzyl-3-(2-methyl-propane-2-sulfinyl)-pro...)
Affinity DataIC50: 2nMAssay Description:In vitro inhibition of Human kideny reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50022582(Diastereomer-5-[2-[2-Benzyl-3-(2-methyl-propane-2-...)
Affinity DataIC50: 3nMAssay Description:In vitro inhibition of dog plasma reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50022587(5-[2-(2-tert-Butylsulfanylmethyl-3-phenyl-propiony...)
Affinity DataIC50: 4nMAssay Description:In vitro inhibition of Human kideny reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50022588({2-[1-(4-Butylcarbamoyl-1-cyclohexylmethyl-2-hydro...)
Affinity DataIC50: 4nMAssay Description:In vitro inhibition of Human kideny reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50022584(2-Benzyl-5,5-dimethyl-4-oxo-hexanoic acid [1-(4-bu...)
Affinity DataIC50: 6nMAssay Description:In vitro inhibition of Human kideny reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50022590(2,2-Dimethyl-propionic acid 1-[1-(4-butylcarbamoyl...)
Affinity DataIC50: 7nMAssay Description:In vitro inhibition of Human kideny reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50022859(Pro-His-Prp-Phe-His-Leu(psi)[CH2NH]Val-Ile-His-Lys...)
Affinity DataIC50: 10nMAssay Description:In vitro inhibition of Human kideny reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50022589({1-[1-(4-{1-[1-Carbamoyl-2-(3H-imidazol-4-yl)-ethy...)
Affinity DataIC50: 15nMAssay Description:In vitro inhibition of Human kideny reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50022581(2,2-Dimethyl-propionic acid 1-[1-(4-butylcarbamoyl...)
Affinity DataIC50: 20nMAssay Description:In vitro inhibition of Human kideny reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50022591(2,2-Dimethyl-propionic acid 1-[1-(4-{1-[1-carbamoy...)
Affinity DataIC50: 20nMAssay Description:In vitro inhibition of Human kideny reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50022585(5-[2-[2-(2,2-Dimethyl-propionylamino)-3-phenyl-pro...)
Affinity DataIC50: 20nMAssay Description:In vitro inhibition of Human kideny reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Rat)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50022582(Diastereomer-5-[2-[2-Benzyl-3-(2-methyl-propane-2-...)
Affinity DataIC50: 400nMAssay Description:In vitro inhibition of rat plasma reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin D(Bovine)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50022582(Diastereomer-5-[2-[2-Benzyl-3-(2-methyl-propane-2-...)
Affinity DataIC50: 3.20E+3nMAssay Description:In vitro inhibition of bovine cathepsin DMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50022582(Diastereomer-5-[2-[2-Benzyl-3-(2-methyl-propane-2-...)
Affinity DataIC50: 8.20E+3nMAssay Description:In vitro inhibition of porcine plasma reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed