Report error Found 9 Enz. Inhib. hit(s) with all data for entry = 50008467
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
The Walter and Eliza Hall Institute of Medical Research
Curated by ChEMBL
The Walter and Eliza Hall Institute of Medical Research
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of Plasmodium falciparum DHODH expressed in Escherichia coli using L-dihydroorotate as substrateMore data for this Ligand-Target Pair
3D Structure (crystal)TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
The Walter and Eliza Hall Institute of Medical Research
Curated by ChEMBL
The Walter and Eliza Hall Institute of Medical Research
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of Plasmodium falciparum DHODH expressed in Escherichia coli using L-dihydroorotate as substrateMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Human)
The Walter and Eliza Hall Institute of Medical Research
Curated by ChEMBL
The Walter and Eliza Hall Institute of Medical Research
Curated by ChEMBL
Affinity DataIC50: 1.58E+3nMAssay Description:Inhibition of human ERG by patch clamp methodMore data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
The Walter and Eliza Hall Institute of Medical Research
Curated by ChEMBL
The Walter and Eliza Hall Institute of Medical Research
Curated by ChEMBL
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of human DHODH expressed in Escherichia coli using L-dihydroorotate as substrateMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Human)
The Walter and Eliza Hall Institute of Medical Research
Curated by ChEMBL
The Walter and Eliza Hall Institute of Medical Research
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Human)
The Walter and Eliza Hall Institute of Medical Research
Curated by ChEMBL
The Walter and Eliza Hall Institute of Medical Research
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Cav1.2 (unknown origin)More data for this Ligand-Target Pair
TargetSodium channel protein type 5 subunit alpha(Human)
The Walter and Eliza Hall Institute of Medical Research
Curated by ChEMBL
The Walter and Eliza Hall Institute of Medical Research
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Nav1.5 (unknown origin)More data for this Ligand-Target Pair
TargetCytochrome P450 3A4(Human)
The Walter and Eliza Hall Institute of Medical Research
Curated by ChEMBL
The Walter and Eliza Hall Institute of Medical Research
Curated by ChEMBL
Affinity DataKi: 90nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
TargetCytochrome P450 3A4(Human)
The Walter and Eliza Hall Institute of Medical Research
Curated by ChEMBL
The Walter and Eliza Hall Institute of Medical Research
Curated by ChEMBL
Affinity DataKi: 156nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
