Compile Data Set for Download or QSAR
Report error Found 11 Enz. Inhib. hit(s) with all data for entry = 50009273
TargetIntegrase(Human immunodeficiency virus type 1)
Wuhan University of Technology

Curated by ChEMBL
LigandPNGBDBM50062551(Dolutegravir | GSK1349572 | CHEBI:76010 | S-349572)
Affinity DataEC50:  3.60nMAssay Description:Inhibition of HIV-1 NL4-3 integrase E92Q/N155H double mutantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus 2)
Wuhan University of Technology

Curated by ChEMBL
LigandPNGBDBM50062551(Dolutegravir | GSK1349572 | CHEBI:76010 | S-349572)
Affinity DataEC50:  2.30nMAssay Description:Inhibition of wild type HIV-2 ROD9 integraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
Wuhan University of Technology

Curated by ChEMBL
LigandPNGBDBM50062551(Dolutegravir | GSK1349572 | CHEBI:76010 | S-349572)
Affinity DataEC50:  1.5nMAssay Description:Inhibition of HIV-1 NL4-3 integrase T97A/Y143C double mutantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
Wuhan University of Technology

Curated by ChEMBL
LigandPNGBDBM50062551(Dolutegravir | GSK1349572 | CHEBI:76010 | S-349572)
Affinity DataEC50:  6.80nMAssay Description:Inhibition of HIV-1 NL4-3 integrase G140S/Q148R double mutantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Wuhan University of Technology

Curated by ChEMBL
LigandPNGBDBM50526705(CHEMBL106731)
Affinity DataEC50:  1.60E+3nMAssay Description:Inhibition of wild type HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
Wuhan University of Technology

Curated by ChEMBL
LigandPNGBDBM50062551(Dolutegravir | GSK1349572 | CHEBI:76010 | S-349572)
Affinity DataEC50:  1.5nMAssay Description:Inhibition of wild type HIV-1 NL4-3 integraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Wuhan University of Technology

Curated by ChEMBL
LigandPNGBDBM50002692(1-((2R,4S,5S)-4-Azido-5-hydroxymethyl-tetrahydro-f...)
Affinity DataIC50: 12.7nMAssay Description:Inhibition of HIV-1 reverse transcriptase after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Wuhan University of Technology

Curated by ChEMBL
LigandPNGBDBM50526706(CHEMBL4545676)
Affinity DataIC50: 270nMAssay Description:Inhibition of HIV-1 reverse transcriptase after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Wuhan University of Technology

Curated by ChEMBL
LigandPNGBDBM192670(3-(6-methoxy-3,4-dihydroquinolin-1(2H)-yl)-1-(4-o-...)
Affinity DataIC50: 1.24E+4nMAssay Description:Inhibition of HIV-1 reverse transcriptase after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Wuhan University of Technology

Curated by ChEMBL
LigandPNGBDBM192678(1-(4-(3-chlorophenyl)piperazin-1-yl)-3-(6-methoxy-...)
Affinity DataIC50: 1.86E+4nMAssay Description:Inhibition of HIV-1 reverse transcriptase after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Wuhan University of Technology

Curated by ChEMBL
LigandPNGBDBM192669(3-(6-methoxy-3,4-dihydroquinolin-1(2H)-yl)-1-(4-ph...)
Affinity DataIC50: 2.42E+4nMAssay Description:Inhibition of HIV-1 reverse transcriptase after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed