Compile Data Set for Download or QSAR
Report error Found 14 Enz. Inhib. hit(s) with all data for entry = 50008097
Target5-hydroxytryptamine receptor 4(Human)
Normandie Univ

Curated by ChEMBL
LigandPNGBDBM50515600(CHEMBL4580044)
Affinity DataEC50:  1.40nMAssay Description:Partial agonist activity at human HA-tagged 5HT4 receptor expressed in COS7 cells assessed as induction of cAMP production measured after 10 mins by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Human)
Normandie Univ

Curated by ChEMBL
LigandPNGBDBM50515598(CHEMBL4526049)
Affinity DataEC50:  2.80nMAssay Description:Partial agonist activity at human HA-tagged 5HT4 receptor expressed in COS7 cells assessed as induction of cAMP production measured after 10 mins by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Human)
Normandie Univ

Curated by ChEMBL
LigandPNGBDBM50515599(CHEMBL4457426)
Affinity DataEC50:  4.5nMAssay Description:Partial agonist activity at human HA-tagged 5HT4 receptor expressed in COS7 cells assessed as induction of cAMP production measured after 10 mins by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Human)
Normandie Univ

Curated by ChEMBL
LigandPNGBDBM50515598(CHEMBL4526049)
Affinity DataKi:  5.90nMAssay Description:Binding affinity to recombinant human brain 5HT4 receptor by radio ligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Human)
Normandie Univ

Curated by ChEMBL
LigandPNGBDBM50515598(CHEMBL4526049)
Affinity DataIC50: 7.5nMAssay Description:Displacement of [3H]-GR 113808 from recombinant human brain 5HT4 receptor measured after 60 mins by radio ligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Normandie Univ

Curated by ChEMBL
LigandPNGBDBM8960(2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2...)
Affinity DataIC50: 12nMAssay Description:Inhibition of human erythrocytes AChE assessed as reduction in 5-thio-2-nitrobenzoate anion formation using acetylthiocholine iodide as substrate pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target5-hydroxytryptamine receptor 4(Human)
Normandie Univ

Curated by ChEMBL
LigandPNGBDBM50515600(CHEMBL4580044)
Affinity DataKi:  13nMAssay Description:Binding affinity to recombinant human brain 5HT4 receptor by radio ligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Human)
Normandie Univ

Curated by ChEMBL
LigandPNGBDBM50515600(CHEMBL4580044)
Affinity DataIC50: 15nMAssay Description:Displacement of [3H]-GR 113808 from recombinant human brain 5HT4 receptor measured after 60 mins by radio ligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Human)
Normandie Univ

Curated by ChEMBL
LigandPNGBDBM50515599(CHEMBL4457426)
Affinity DataKi:  101nMAssay Description:Binding affinity to recombinant human brain 5HT4 receptor by radio ligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Human)
Normandie Univ

Curated by ChEMBL
LigandPNGBDBM50515599(CHEMBL4457426)
Affinity DataIC50: 101nMAssay Description:Displacement of [3H]-GR 113808 from recombinant human brain 5HT4 receptor measured after 60 mins by radio ligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Normandie Univ

Curated by ChEMBL
LigandPNGBDBM50515598(CHEMBL4526049)
Affinity DataIC50: 138nMAssay Description:Inhibition of human erythrocytes AChE assessed as reduction in 5-thio-2-nitrobenzoate anion formation using acetylthiocholine iodide as substrate pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Human)
Normandie Univ

Curated by ChEMBL
LigandPNGBDBM10755([3H]-5-HT | 5-Hydroxy Tryptamine | 2-imino-1-methy...)
Affinity DataKi:  246nMAssay Description:Binding affinity to recombinant human brain 5HT4 receptor by radio ligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Human)
Normandie Univ

Curated by ChEMBL
LigandPNGBDBM10755([3H]-5-HT | 5-Hydroxy Tryptamine | 2-imino-1-methy...)
Affinity DataIC50: 323nMAssay Description:Displacement of [3H]-GR 113808 from recombinant human brain 5HT4 receptor measured after 60 mins by radio ligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Normandie Univ

Curated by ChEMBL
LigandPNGBDBM50515601(CHEMBL4527729)
Affinity DataIC50: 535nMAssay Description:Inhibition of human erythrocytes AChE assessed as reduction in 5-thio-2-nitrobenzoate anion formation using acetylthiocholine iodide as substrate pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed