Report error Found 34 Enz. Inhib. hit(s) with all data for entry = 50008254
TargetMitogen-activated protein kinase 14(Human)
University of Minnesota Twin Cities
Curated by ChEMBL
University of Minnesota Twin Cities
Curated by ChEMBL
Affinity DataKd: 2.20nMAssay Description:Binding affinity to wild-type human full length p38-alpha (M1 to S360 residues) expressed in bacterial expression system by Kinomescan methodMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Human)
University of Minnesota Twin Cities
Curated by ChEMBL
University of Minnesota Twin Cities
Curated by ChEMBL
Affinity DataKd: 120nMAssay Description:Binding affinity to wild-type human full length p38-alpha (M1 to S360 residues) expressed in bacterial expression system by Kinomescan methodMore data for this Ligand-Target Pair
Affinity DataKd: 940nMAssay Description:Binding affinity to human partial length BRD4 bromodomain 2 long isoform (K333 to E460 residues) expressed in bacterial expression system by BROMOsca...More data for this Ligand-Target Pair
Affinity DataKd: 1.10E+3nMAssay Description:Binding affinity to human partial length BRD4 bromodomain 1 long isoform (N44 to E168 residues) expressed in bacterial expression system by BROMOscan...More data for this Ligand-Target Pair
Affinity DataKd: 1.20E+3nMAssay Description:Binding affinity to human partial length BRD4 bromodomain 1 long isoform (N44 to E168 residues) expressed in bacterial expression system by BROMOscan...More data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of biotinylated histone H4 peptide binding to BRD4 bromodomain 1 (44 to 168 residues) (unknown origin) after 60 mins by Alphascreen methodMore data for this Ligand-Target Pair
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of biotinylated histone H4 peptide binding to BRD4 bromodomain 1 (44 to 168 residues) (unknown origin) after 60 mins by Alphascreen methodMore data for this Ligand-Target Pair
Affinity DataKd: 2.10E+3nMAssay Description:Binding affinity to human partial length BRD4 bromodomain 2 long isoform (K333 to E460 residues) expressed in bacterial expression system by BROMOsca...More data for this Ligand-Target Pair
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of BRD4 bromodomain 1 (unknown origin) expressed in Escherichia coli Bl21(DE3)-pRARE cells by fluorescence anisotropyMore data for this Ligand-Target Pair
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of BRD4 bromodomain 1 (unknown origin) expressed in Escherichia coli Bl21(DE3)-pRARE cells by fluorescence anisotropyMore data for this Ligand-Target Pair
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of BRD4 bromodomain 1 (unknown origin) expressed in Escherichia coli Bl21(DE3)-pRARE cells by fluorescence anisotropyMore data for this Ligand-Target Pair
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of BRD4 bromodomain 1 (unknown origin) expressed in Escherichia coli Bl21(DE3)-pRARE cells by fluorescence anisotropyMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Human)
University of Minnesota Twin Cities
Curated by ChEMBL
University of Minnesota Twin Cities
Curated by ChEMBL
Affinity DataKd: 5.00E+3nMAssay Description:Binding affinity to wild-type human full length p38-alpha (M1 to S360 residues) expressed in bacterial expression system by Kinomescan methodMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Human)
University of Minnesota Twin Cities
Curated by ChEMBL
University of Minnesota Twin Cities
Curated by ChEMBL
Affinity DataKd: 6.50E+3nMAssay Description:Binding affinity to wild-type human full length p38-alpha (M1 to S360 residues) expressed in bacterial expression system by Kinomescan methodMore data for this Ligand-Target Pair
Affinity DataIC50: 9.70E+3nMAssay Description:Inhibition of BRD4 bromodomain 1 (unknown origin) expressed in Escherichia coli Bl21(DE3)-pRARE cells by fluorescence anisotropyMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of BRD4 bromodomain 1 (unknown origin) expressed in Escherichia coli Bl21(DE3)-pRARE cells by fluorescence anisotropyMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of BRD4 bromodomain 1 (unknown origin) expressed in Escherichia coli Bl21(DE3)-pRARE cells by fluorescence anisotropyMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Human)
University of Minnesota Twin Cities
Curated by ChEMBL
University of Minnesota Twin Cities
Curated by ChEMBL
Affinity DataKd: >2.50E+4nMAssay Description:Binding affinity to wild-type human full length p38-alpha (M1 to S360 residues) expressed in bacterial expression system by Kinomescan methodMore data for this Ligand-Target Pair
Affinity DataIC50: 2.70E+4nMAssay Description:Inhibition of biotinylated histone H4 peptide binding to BRD4 bromodomain 1 (44 to 168 residues) (unknown origin) after 60 mins by Alphascreen methodMore data for this Ligand-Target Pair
Affinity DataIC50: 6.10E+4nMAssay Description:Inhibition of BRD4 bromodomain 1 (unknown origin) expressed in Escherichia coli Bl21(DE3)-pRARE cells by fluorescence anisotropyMore data for this Ligand-Target Pair
Affinity DataKd: 7.80E+4nMAssay Description:Binding affinity to human partial length CREBBP (R1081 to G1197 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
Affinity DataIC50: 9.70E+4nMAssay Description:Inhibition of BRD4 bromodomain 1 (unknown origin) expressed in Escherichia coli Bl21(DE3)-pRARE cells by fluorescence anisotropyMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of BRD4 bromodomain 1 (unknown origin) expressed in Escherichia coli Bl21(DE3)-pRARE cells by fluorescence anisotropyMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of BRD4 bromodomain 1 (unknown origin) expressed in Escherichia coli Bl21(DE3)-pRARE cells by fluorescence anisotropyMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of BRD4 bromodomain 1 (unknown origin) expressed in Escherichia coli Bl21(DE3)-pRARE cells by fluorescence anisotropyMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of BRD4 bromodomain 1 (unknown origin) expressed in Escherichia coli Bl21(DE3)-pRARE cells by fluorescence anisotropyMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of BRD4 bromodomain 1 (unknown origin) expressed in Escherichia coli Bl21(DE3)-pRARE cells by fluorescence anisotropyMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of BRD4 bromodomain 1 (unknown origin) expressed in Escherichia coli Bl21(DE3)-pRARE cells by fluorescence anisotropyMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of BRD4 bromodomain 1 (unknown origin) expressed in Escherichia coli Bl21(DE3)-pRARE cells by fluorescence anisotropyMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of BRD4 bromodomain 1 (unknown origin) expressed in Escherichia coli Bl21(DE3)-pRARE cells by fluorescence anisotropyMore data for this Ligand-Target Pair
Affinity DataKd: >1.00E+5nMAssay Description:Binding affinity to human partial length CREBBP (R1081 to G1197 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
TargetProbable global transcription activator SNF2L2(Human)
University of Minnesota Twin Cities
Curated by ChEMBL
University of Minnesota Twin Cities
Curated by ChEMBL
Affinity DataKd: >1.00E+5nMAssay Description:Binding affinity to human partial length SMARCA2 (S1377 to Q1486 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
TargetProbable global transcription activator SNF2L2(Human)
University of Minnesota Twin Cities
Curated by ChEMBL
University of Minnesota Twin Cities
Curated by ChEMBL
Affinity DataKd: >1.00E+5nMAssay Description:Binding affinity to human partial length SMARCA2 (S1377 to Q1486 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Human)
University of Minnesota Twin Cities
Curated by ChEMBL
University of Minnesota Twin Cities
Curated by ChEMBL
Affinity DataKd: >2.00E+5nMAssay Description:Binding affinity to wild-type human full length p38-alpha (M1 to S360 residues) expressed in bacterial expression system by Kinomescan methodMore data for this Ligand-Target Pair



















