Compile Data Set for Download or QSAR
Report error Found 10 Enz. Inhib. hit(s) with all data for entry = 50008477
TargetUtrophin(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50519636(BMN 195 | BMN-195 | Ezutromid | SMT-C1100 | SMTC-1...)
Affinity DataEC50:  110nMAssay Description:Activation of human utrophin-1 in mouse mdx myoblasts by H2K-mdx utrnA-luc assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetUtrophin(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50519637(CHEMBL4550375)
Affinity DataEC50:  370nMAssay Description:Activation of human utrophin-1 in mouse mdx myoblasts by H2K-mdx utrnA-luc assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetUtrophin(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50519637(CHEMBL4550375)
Affinity DataEC50: >1.00E+4nMAssay Description:Activation of human utrophin-1 in iDMD cells by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetUtrophin(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50519638(CHEMBL4442951)
Affinity DataEC50:  8.35E+3nMAssay Description:Activation of human utrophin-1 in iDMD cells by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetUtrophin(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50519636(BMN 195 | BMN-195 | Ezutromid | SMT-C1100 | SMTC-1...)
Affinity DataEC50:  1.28E+3nMAssay Description:Activation of human utrophin-1 in iDMD cells by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetUtrophin(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50519638(CHEMBL4442951)
Affinity DataEC50:  120nMAssay Description:Activation of human utrophin-1 in mouse mdx myoblasts by H2K-mdx utrnA-luc assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50519637(CHEMBL4550375)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of monoamino oxidase B (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50519636(BMN 195 | BMN-195 | Ezutromid | SMT-C1100 | SMTC-1...)
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibition of CYP1A2 in human liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetMultidrug and toxin extrusion protein 1(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50519637(CHEMBL4550375)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MATE1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50121975((6-Methoxy-quinolin-4-yl)-(5-vinyl-1-aza-bicyclo[2...)
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of human CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed