Compile Data Set for Download or QSAR
Report error Found 65 Enz. Inhib. hit(s) with all data for entry = 50006743
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
South China Agricultural University

Curated by ChEMBL
LigandPNGBDBM50502852(CHEMBL4464755)
Affinity DataIC50: 220nMAssay Description:Inhibition of PDE4B in human U937 cells using [3H] cAMP as substrate incubated for 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
South China Agricultural University

Curated by ChEMBL
LigandPNGBDBM50502858(CHEMBL4451855)
Affinity DataIC50: 380nMAssay Description:Inhibition of PDE4B in human U937 cells using [3H] cAMP as substrate incubated for 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
South China Agricultural University

Curated by ChEMBL
LigandPNGBDBM50502854(CHEMBL4574643)
Affinity DataIC50: 1.05E+3nMAssay Description:Inhibition of PDE4B in human U937 cells using [3H] cAMP as substrate incubated for 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
South China Agricultural University

Curated by ChEMBL
LigandPNGBDBM50502852(CHEMBL4464755)
Affinity DataIC50: 1.36E+3nMAssay Description:Inhibition of PDE4B in human PBMC assessed as inhibition in LPS-induced TNFalpha production preincubated for 30 mins followed by LPS stimulation for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
South China Agricultural University

Curated by ChEMBL
LigandPNGBDBM50502858(CHEMBL4451855)
Affinity DataIC50: 1.65E+3nMAssay Description:Inhibition of PDE4B in human PBMC assessed as inhibition in LPS-induced TNFalpha production preincubated for 30 mins followed by LPS stimulation for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
South China Agricultural University

Curated by ChEMBL
LigandPNGBDBM14361(Adeo | 4-(3-cyclopentyloxy-4-methoxy-phenyl)pyrrol...)
Affinity DataIC50: 1.69E+3nMAssay Description:Inhibition of PDE4D in human U937 cells using [3H]cAMP as substrate incubated for 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
South China Agricultural University

Curated by ChEMBL
LigandPNGBDBM14361(Adeo | 4-(3-cyclopentyloxy-4-methoxy-phenyl)pyrrol...)
Affinity DataIC50: 1.82E+3nMAssay Description:Inhibition of PDE4B in human U937 cells using [3H] cAMP as substrate incubated for 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
South China Agricultural University

Curated by ChEMBL
LigandPNGBDBM50502853(CHEMBL4578186)
Affinity DataIC50: 1.85E+3nMAssay Description:Inhibition of PDE4B in human U937 cells using [3H] cAMP as substrate incubated for 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
South China Agricultural University

Curated by ChEMBL
LigandPNGBDBM50502864(CHEMBL4571089)
Affinity DataIC50: 1.85E+3nMAssay Description:Inhibition of PDE4B in human U937 cells using [3H] cAMP as substrate incubated for 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
South China Agricultural University

Curated by ChEMBL
LigandPNGBDBM50502859(CHEMBL4585341)
Affinity DataIC50: 2.03E+3nMAssay Description:Inhibition of PDE4B in human U937 cells using [3H] cAMP as substrate incubated for 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
South China Agricultural University

Curated by ChEMBL
LigandPNGBDBM50502865(CHEMBL4470613)
Affinity DataIC50: 3.86E+3nMAssay Description:Inhibition of PDE4B in human U937 cells using [3H] cAMP as substrate incubated for 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
South China Agricultural University

Curated by ChEMBL
LigandPNGBDBM50502867(CHEMBL4447428)
Affinity DataIC50: 3.96E+3nMAssay Description:Inhibition of PDE4B in human U937 cells using [3H] cAMP as substrate incubated for 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
South China Agricultural University

Curated by ChEMBL
LigandPNGBDBM50502860(CHEMBL4537270)
Affinity DataIC50: 4.25E+3nMAssay Description:Inhibition of PDE4B in human U937 cells using [3H] cAMP as substrate incubated for 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
South China Agricultural University

Curated by ChEMBL
LigandPNGBDBM50502852(CHEMBL4464755)
Affinity DataIC50: 5.78E+3nMAssay Description:Inhibition of PDE4D in human U937 cells using [3H]cAMP as substrate incubated for 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
South China Agricultural University

Curated by ChEMBL
LigandPNGBDBM50502866(CHEMBL4472790)
Affinity DataIC50: 6.23E+3nMAssay Description:Inhibition of PDE4B in human U937 cells using [3H] cAMP as substrate incubated for 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
South China Agricultural University

Curated by ChEMBL
LigandPNGBDBM50502864(CHEMBL4571089)
Affinity DataIC50: 6.36E+3nMAssay Description:Inhibition of PDE4B in human PBMC assessed as inhibition in LPS-induced TNFalpha production preincubated for 30 mins followed by LPS stimulation for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
South China Agricultural University

Curated by ChEMBL
LigandPNGBDBM50502858(CHEMBL4451855)
Affinity DataIC50: 6.66E+3nMAssay Description:Inhibition of PDE4D in human U937 cells using [3H]cAMP as substrate incubated for 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
South China Agricultural University

Curated by ChEMBL
LigandPNGBDBM50502854(CHEMBL4574643)
Affinity DataIC50: 7.53E+3nMAssay Description:Inhibition of PDE4B in human PBMC assessed as inhibition in LPS-induced TNFalpha production preincubated for 30 mins followed by LPS stimulation for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
South China Agricultural University

Curated by ChEMBL
LigandPNGBDBM50502863(CHEMBL4542316)
Affinity DataIC50: 8.32E+3nMAssay Description:Inhibition of PDE4B in human U937 cells using [3H] cAMP as substrate incubated for 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
South China Agricultural University

Curated by ChEMBL
LigandPNGBDBM50502857(CHEMBL4529642)
Affinity DataIC50: 8.38E+3nMAssay Description:Inhibition of PDE4B in human U937 cells using [3H] cAMP as substrate incubated for 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
South China Agricultural University

Curated by ChEMBL
LigandPNGBDBM50502856(CHEMBL4571951)
Affinity DataIC50: 8.77E+3nMAssay Description:Inhibition of PDE4B in human U937 cells using [3H] cAMP as substrate incubated for 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
South China Agricultural University

Curated by ChEMBL
LigandPNGBDBM50502853(CHEMBL4578186)
Affinity DataIC50: 1.01E+4nMAssay Description:Inhibition of PDE4D in human U937 cells using [3H]cAMP as substrate incubated for 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
South China Agricultural University

Curated by ChEMBL
LigandPNGBDBM50502859(CHEMBL4585341)
Affinity DataIC50: 1.04E+4nMAssay Description:Inhibition of PDE4B in human PBMC assessed as inhibition in LPS-induced TNFalpha production preincubated for 30 mins followed by LPS stimulation for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
South China Agricultural University

Curated by ChEMBL
LigandPNGBDBM50502859(CHEMBL4585341)
Affinity DataIC50: 1.12E+4nMAssay Description:Inhibition of PDE4D in human U937 cells using [3H]cAMP as substrate incubated for 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
South China Agricultural University

Curated by ChEMBL
LigandPNGBDBM50502854(CHEMBL4574643)
Affinity DataIC50: 1.13E+4nMAssay Description:Inhibition of PDE4D in human U937 cells using [3H]cAMP as substrate incubated for 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
South China Agricultural University

Curated by ChEMBL
LigandPNGBDBM14361(Adeo | 4-(3-cyclopentyloxy-4-methoxy-phenyl)pyrrol...)
Affinity DataIC50: 1.14E+4nMAssay Description:Inhibition of PDE4B in human PBMC assessed as inhibition in LPS-induced TNFalpha production preincubated for 30 mins followed by LPS stimulation for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
South China Agricultural University

Curated by ChEMBL
LigandPNGBDBM50502853(CHEMBL4578186)
Affinity DataIC50: 1.26E+4nMAssay Description:Inhibition of PDE4B in human PBMC assessed as inhibition in LPS-induced TNFalpha production preincubated for 30 mins followed by LPS stimulation for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
South China Agricultural University

Curated by ChEMBL
LigandPNGBDBM50502864(CHEMBL4571089)
Affinity DataIC50: 1.38E+4nMAssay Description:Inhibition of PDE4D in human U937 cells using [3H]cAMP as substrate incubated for 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
South China Agricultural University

Curated by ChEMBL
LigandPNGBDBM50502865(CHEMBL4470613)
Affinity DataIC50: 1.58E+4nMAssay Description:Inhibition of PDE4D in human U937 cells using [3H]cAMP as substrate incubated for 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
South China Agricultural University

Curated by ChEMBL
LigandPNGBDBM50502855(CHEMBL4461167)
Affinity DataIC50: 1.65E+4nMAssay Description:Inhibition of PDE4B in human U937 cells using [3H] cAMP as substrate incubated for 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
South China Agricultural University

Curated by ChEMBL
LigandPNGBDBM50502867(CHEMBL4447428)
Affinity DataIC50: 1.79E+4nMAssay Description:Inhibition of PDE4B in human PBMC assessed as inhibition in LPS-induced TNFalpha production preincubated for 30 mins followed by LPS stimulation for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
South China Agricultural University

Curated by ChEMBL
LigandPNGBDBM50502861(CHEMBL4567007)
Affinity DataIC50: 1.84E+4nMAssay Description:Inhibition of PDE4B in human U937 cells using [3H] cAMP as substrate incubated for 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
South China Agricultural University

Curated by ChEMBL
LigandPNGBDBM50502860(CHEMBL4537270)
Affinity DataIC50: 1.93E+4nMAssay Description:Inhibition of PDE4B in human PBMC assessed as inhibition in LPS-induced TNFalpha production preincubated for 30 mins followed by LPS stimulation for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
South China Agricultural University

Curated by ChEMBL
LigandPNGBDBM50502862(CHEMBL4537714)
Affinity DataIC50: 2.05E+4nMAssay Description:Inhibition of PDE4B in human U937 cells using [3H] cAMP as substrate incubated for 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
South China Agricultural University

Curated by ChEMBL
LigandPNGBDBM50502865(CHEMBL4470613)
Affinity DataIC50: 2.09E+4nMAssay Description:Inhibition of PDE4B in human PBMC assessed as inhibition in LPS-induced TNFalpha production preincubated for 30 mins followed by LPS stimulation for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
South China Agricultural University

Curated by ChEMBL
LigandPNGBDBM50502867(CHEMBL4447428)
Affinity DataIC50: 2.62E+4nMAssay Description:Inhibition of PDE4D in human U937 cells using [3H]cAMP as substrate incubated for 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
South China Agricultural University

Curated by ChEMBL
LigandPNGBDBM50502866(CHEMBL4472790)
Affinity DataIC50: 2.94E+4nMAssay Description:Inhibition of PDE4B in human PBMC assessed as inhibition in LPS-induced TNFalpha production preincubated for 30 mins followed by LPS stimulation for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
South China Agricultural University

Curated by ChEMBL
LigandPNGBDBM50502860(CHEMBL4537270)
Affinity DataIC50: 2.97E+4nMAssay Description:Inhibition of PDE4D in human U937 cells using [3H]cAMP as substrate incubated for 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
South China Agricultural University

Curated by ChEMBL
LigandPNGBDBM50502866(CHEMBL4472790)
Affinity DataIC50: 3.28E+4nMAssay Description:Inhibition of PDE4D in human U937 cells using [3H]cAMP as substrate incubated for 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
South China Agricultural University

Curated by ChEMBL
LigandPNGBDBM50502857(CHEMBL4529642)
Affinity DataIC50: 3.65E+4nMAssay Description:Inhibition of PDE4B in human PBMC assessed as inhibition in LPS-induced TNFalpha production preincubated for 30 mins followed by LPS stimulation for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
South China Agricultural University

Curated by ChEMBL
LigandPNGBDBM50502856(CHEMBL4571951)
Affinity DataIC50: 3.67E+4nMAssay Description:Inhibition of PDE4D in human U937 cells using [3H]cAMP as substrate incubated for 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
South China Agricultural University

Curated by ChEMBL
LigandPNGBDBM50502863(CHEMBL4542316)
Affinity DataIC50: 3.74E+4nMAssay Description:Inhibition of PDE4D in human U937 cells using [3H]cAMP as substrate incubated for 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
South China Agricultural University

Curated by ChEMBL
LigandPNGBDBM50502857(CHEMBL4529642)
Affinity DataIC50: 3.86E+4nMAssay Description:Inhibition of PDE4D in human U937 cells using [3H]cAMP as substrate incubated for 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
South China Agricultural University

Curated by ChEMBL
LigandPNGBDBM50502863(CHEMBL4542316)
Affinity DataIC50: 4.16E+4nMAssay Description:Inhibition of PDE4B in human PBMC assessed as inhibition in LPS-induced TNFalpha production preincubated for 30 mins followed by LPS stimulation for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
South China Agricultural University

Curated by ChEMBL
LigandPNGBDBM50502856(CHEMBL4571951)
Affinity DataIC50: 4.32E+4nMAssay Description:Inhibition of PDE4B in human PBMC assessed as inhibition in LPS-induced TNFalpha production preincubated for 30 mins followed by LPS stimulation for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Human)
South China Agricultural University

Curated by ChEMBL
LigandPNGBDBM50502858(CHEMBL4451855)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of PDE7A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Human)
South China Agricultural University

Curated by ChEMBL
LigandPNGBDBM50502852(CHEMBL4464755)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of PDE3B (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Human)
South China Agricultural University

Curated by ChEMBL
LigandPNGBDBM50502852(CHEMBL4464755)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of PDE11A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Human)
South China Agricultural University

Curated by ChEMBL
LigandPNGBDBM50502858(CHEMBL4451855)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of PDE11A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetHigh affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A(Human)
South China Agricultural University

Curated by ChEMBL
LigandPNGBDBM50502858(CHEMBL4451855)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of PDE8A1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
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