Report error Found 15 Enz. Inhib. hit(s) with all data for entry = 50009499
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Human)
Peking Union Medical College
Curated by ChEMBL
Peking Union Medical College
Curated by ChEMBL
Affinity DataIC50: 6.20nMAssay Description:Inhibition of wild type BCR/Abl (unknown origin) transfected in mouse Ba/F3 cells assessed as inhibition of cell proliferation measured after 72 hrs ...More data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Human)
Peking Union Medical College
Curated by ChEMBL
Peking Union Medical College
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of wild type BCR/Abl (unknown origin) transfected in mouse Ba/F3 cells assessed as inhibition of cell proliferation measured after 72 hrs ...More data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Human)
Peking Union Medical College
Curated by ChEMBL
Peking Union Medical College
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of BCR/Abl F317I mutant (unknown origin) transfected in mouse Ba/F3 cells assessed as inhibition of cell proliferation measured after 72 h...More data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Human)
Peking Union Medical College
Curated by ChEMBL
Peking Union Medical College
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Inhibition of BCR/Abl Q252H mutant (unknown origin) transfected in mouse Ba/F3 cells assessed as inhibition of cell proliferation measured after 72 h...More data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Human)
Peking Union Medical College
Curated by ChEMBL
Peking Union Medical College
Curated by ChEMBL
Affinity DataIC50: 22nMAssay Description:Inhibition of BCR/Abl M351T mutant (unknown origin) transfected in mouse Ba/F3 cells assessed as inhibition of cell proliferation measured after 72 h...More data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Human)
Peking Union Medical College
Curated by ChEMBL
Peking Union Medical College
Curated by ChEMBL
Affinity DataIC50: 24nMAssay Description:Inhibition of BCR/Abl M351T mutant (unknown origin) transfected in mouse Ba/F3 cells assessed as inhibition of cell proliferation measured after 72 h...More data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Human)
Peking Union Medical College
Curated by ChEMBL
Peking Union Medical College
Curated by ChEMBL
Affinity DataIC50: 31nMAssay Description:Inhibition of BCR/Abl F317I mutant (unknown origin) transfected in mouse Ba/F3 cells assessed as inhibition of cell proliferation measured after 72 h...More data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Human)
Peking Union Medical College
Curated by ChEMBL
Peking Union Medical College
Curated by ChEMBL
Affinity DataIC50: 37nMAssay Description:Inhibition of BCR/Abl Q252H mutant (unknown origin) transfected in mouse Ba/F3 cells assessed as inhibition of cell proliferation measured after 72 h...More data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Human)
Peking Union Medical College
Curated by ChEMBL
Peking Union Medical College
Curated by ChEMBL
Affinity DataIC50: 144nMAssay Description:Inhibition of wild type BCR/Abl (unknown origin) transfected in mouse Ba/F3 cells assessed as inhibition of cell proliferation measured after 72 hrs ...More data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Human)
Peking Union Medical College
Curated by ChEMBL
Peking Union Medical College
Curated by ChEMBL
Affinity DataIC50: 318nMAssay Description:Inhibition of BCR/Abl Y253F mutant (unknown origin) transfected in mouse Ba/F3 cells assessed as inhibition of cell proliferation measured after 72 h...More data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Human)
Peking Union Medical College
Curated by ChEMBL
Peking Union Medical College
Curated by ChEMBL
Affinity DataIC50: 347nMAssay Description:Inhibition of BCR/Abl Y253F mutant (unknown origin) transfected in mouse Ba/F3 cells assessed as inhibition of cell proliferation measured after 72 h...More data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Human)
Peking Union Medical College
Curated by ChEMBL
Peking Union Medical College
Curated by ChEMBL
Affinity DataIC50: 364nMAssay Description:Inhibition of BCR/Abl F317I mutant (unknown origin) transfected in mouse Ba/F3 cells assessed as inhibition of cell proliferation measured after 72 h...More data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Human)
Peking Union Medical College
Curated by ChEMBL
Peking Union Medical College
Curated by ChEMBL
Affinity DataIC50: 487nMAssay Description:Inhibition of BCR/Abl Q252H mutant (unknown origin) transfected in mouse Ba/F3 cells assessed as inhibition of cell proliferation measured after 72 h...More data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Human)
Peking Union Medical College
Curated by ChEMBL
Peking Union Medical College
Curated by ChEMBL
Affinity DataIC50: 799nMAssay Description:Inhibition of BCR/Abl M351T mutant (unknown origin) transfected in mouse Ba/F3 cells assessed as inhibition of cell proliferation measured after 72 h...More data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Human)
Peking Union Medical College
Curated by ChEMBL
Peking Union Medical College
Curated by ChEMBL
Affinity DataIC50: 8.78E+3nMAssay Description:Inhibition of BCR/Abl Y253F mutant (unknown origin) transfected in mouse Ba/F3 cells assessed as inhibition of cell proliferation measured after 72 h...More data for this Ligand-Target Pair
