Report error Found 108 Enz. Inhib. hit(s) with all data for entry = 50008488
Affinity DataEC50: 1.40nMAssay Description:Agonist activity at human CB1 receptor expressed in CHO cell membranes assessed as increase in G-protein coupling by measuring [35S]GTPgammaS binding...More data for this Ligand-Target Pair
3D Structure (crystal)
Affinity DataEC50: 1.70nMAssay Description:Positive allosteric modulatory activity at human CB1R expressed in CHO-K1 cells assessed as increase in CP55940-induced inhibition of forskolin-induc...More data for this Ligand-Target Pair
Affinity DataEC50: 2.20nMAssay Description:Positive allosteric modulatory activity at human CB1R expressed in CHO-K1 cells assessed as increase in CP55940-induced inhibition of forskolin-induc...More data for this Ligand-Target Pair
Affinity DataEC50: 3.90nMAssay Description:Allosteric agonist activity at human CB1R expressed in CHO-K1 cells assessed as inhibition of forskolin-induced cAMP accumulation after 90 mins by hi...More data for this Ligand-Target Pair
Affinity DataEC50: 4.30nMAssay Description:Allosteric agonist activity at human CB1R expressed in CHO-K1 cells assessed as inhibition of forskolin-induced cAMP accumulation after 90 mins by hi...More data for this Ligand-Target Pair
Affinity DataKi: 4.80nMAssay Description:Displacement of [3H]SR141716A from human CB1R receptor expressed in CHO cell membranes after 2 hrs by liquid scintillation spectrometry analysisMore data for this Ligand-Target Pair
Affinity DataKi: 5.20nMAssay Description:Displacement of [3H]SR141716A from human CB1R receptor expressed in CHO cell membranes after 2 hrs by liquid scintillation spectrometry analysisMore data for this Ligand-Target Pair
Affinity DataEC50: 8.10nMAssay Description:Positive allosteric modulatory activity at human CB1R expressed in CHO-K1 cells assessed as increase in CP55940-induced inhibition of forskolin-induc...More data for this Ligand-Target Pair
Affinity DataEC50: 9nMAssay Description:Positive allosteric modulatory activity at N-terminal GFP-tagged rat CB1R receptor expressed in HEK293 cells assessed as CP55940 EC50 for inhibition ...More data for this Ligand-Target Pair
Affinity DataEC50: 9.10nMAssay Description:Positive allosteric modulatory activity at human CB1R expressed in CHO-K1 cells assessed as increase in CP55940-induced inhibition of forskolin-stimu...More data for this Ligand-Target Pair
Affinity DataEC50: 10nMAssay Description:Positive allosteric modulatory activity at N-terminal GFP-tagged rat CB1R receptor expressed in HEK293 cells assessed as CP55940 EC50 for inhibition ...More data for this Ligand-Target Pair
Affinity DataEC50: 10nMAssay Description:Positive allosteric modulatory activity at N-terminal GFP-tagged rat CB1R receptor expressed in HEK293 cells assessed as CP55940 EC50 for inhibition ...More data for this Ligand-Target Pair
Affinity DataEC50: 12nMAssay Description:Positive allosteric modulatory activity at N-terminal GFP-tagged rat CB1R receptor expressed in HEK293 cells assessed as CP55940 EC50 for inhibition ...More data for this Ligand-Target Pair
Affinity DataEC50: 14nMAssay Description:Positive allosteric modulatory activity at N-terminal GFP-tagged rat CB1R receptor expressed in HEK293 cells assessed as CP55940 EC50 for inhibition ...More data for this Ligand-Target Pair
Affinity DataEC50: 14nMAssay Description:Positive allosteric modulatory activity at human CB1R expressed in CHO-K1 cells assessed as increase in CP55940-induced inhibition of forskolin-induc...More data for this Ligand-Target Pair
Affinity DataEC50: 17nMAssay Description:Positive allosteric modulatory activity at N-terminal GFP-tagged rat CB1R receptor expressed in HEK293 cells assessed as CP55940 EC50 for inhibition ...More data for this Ligand-Target Pair
Affinity DataEC50: 17nMAssay Description:Positive allosteric modulatory activity at N-terminal GFP-tagged rat CB1R receptor expressed in HEK293 cells assessed as CP55940 EC50 for inhibition ...More data for this Ligand-Target Pair
Affinity DataEC50: 17nMAssay Description:Positive allosteric modulatory activity at N-terminal GFP-tagged rat CB1R receptor expressed in HEK293 cells assessed as CP55940 EC50 for inhibition ...More data for this Ligand-Target Pair
Affinity DataEC50: 17nMAssay Description:Positive allosteric modulatory activity at N-terminal GFP-tagged rat CB1R receptor expressed in HEK293 cells assessed as CP55940 EC50 for inhibition ...More data for this Ligand-Target Pair
Affinity DataEC50: 17nMAssay Description:Positive allosteric modulatory activity at N-terminal GFP-tagged rat CB1R receptor expressed in HEK293 cells assessed as CP55940 EC50 for inhibition ...More data for this Ligand-Target Pair
Affinity DataEC50: 18nMAssay Description:Allosteric agonist activity at N-terminal GFP-tagged rat CB1R expressed in HEK293 cells assessed as inhibition of forskolin-induced cAMP production a...More data for this Ligand-Target Pair
Affinity DataEC50: 18nMAssay Description:Positive allosteric modulatory activity at N-terminal GFP-tagged rat CB1R receptor expressed in HEK293 cells assessed as CP55940 EC50 for inhibition ...More data for this Ligand-Target Pair
Affinity DataEC50: 19nMAssay Description:Positive allosteric modulatory activity at N-terminal GFP-tagged rat CB1R receptor expressed in HEK293 cells assessed as CP55940 EC50 for inhibition ...More data for this Ligand-Target Pair
Affinity DataEC50: 20nMAssay Description:Positive allosteric modulatory activity at N-terminal GFP-tagged rat CB1R receptor expressed in HEK293 cells assessed as CP55940 EC50 for inhibition ...More data for this Ligand-Target Pair
Affinity DataEC50: 20nMAssay Description:Positive allosteric modulatory activity at N-terminal GFP-tagged rat CB1R receptor expressed in HEK293 cells assessed as CP55940 EC50 for inhibition ...More data for this Ligand-Target Pair
Affinity DataEC50: 21nMAssay Description:Positive allosteric modulatory activity at human CB1R expressed in CHO-K1 cells assessed as increase in CP55940-induced inhibition of forskolin-stimu...More data for this Ligand-Target Pair
Affinity DataEC50: 22nMAssay Description:Positive allosteric modulatory activity at human CB1R expressed in CHO-K1 cells assessed as increase in CP55940-induced inhibition of forskolin-stimu...More data for this Ligand-Target Pair
Affinity DataEC50: 22nMAssay Description:Positive allosteric modulatory activity at N-terminal GFP-tagged rat CB1R receptor expressed in HEK293 cells assessed as CP55940 EC50 for inhibition ...More data for this Ligand-Target Pair
Affinity DataEC50: 26nMAssay Description:Allosteric agonist activity at N-terminal GFP-tagged rat CB1R expressed in HEK293 cells assessed as inhibition of forskolin-induced cAMP production a...More data for this Ligand-Target Pair
Affinity DataEC50: 27nMAssay Description:Allosteric agonist activity at N-terminal GFP-tagged rat CB1R expressed in HEK293 cells assessed as inhibition of forskolin-induced cAMP production a...More data for this Ligand-Target Pair
Affinity DataEC50: 27nMAssay Description:Positive allosteric modulatory activity at N-terminal GFP-tagged rat CB1R receptor expressed in HEK293 cells assessed as CP55940 EC50 for inhibition ...More data for this Ligand-Target Pair
Affinity DataEC50: 28nMAssay Description:Positive allosteric modulatory activity at human CB1R expressed in CHO-K1 cells assessed as increase in CP55940-induced inhibition of forskolin-stimu...More data for this Ligand-Target Pair
Affinity DataEC50: 33nMAssay Description:Agonist activity at human CB1 receptor expressed in CHO cell membranes assessed as increase in G-protein coupling by measuring [35S]GTPgammaS binding...More data for this Ligand-Target Pair
Affinity DataEC50: 43nMAssay Description:Positive allosteric modulatory activity at human CB1R expressed in CHO-K1 cells assessed as increase in CP55940-induced inhibition of forskolin-stimu...More data for this Ligand-Target Pair
Affinity DataEC50: 47nMAssay Description:Agonist activity at human CB1 receptor expressed in CHO cell membranes assessed as increase in G-protein coupling by measuring [35S]GTPgammaS binding...More data for this Ligand-Target Pair
Affinity DataEC50: 58nMAssay Description:Positive allosteric modulatory activity at human CB1R expressed in CHO-K1 cells assessed as increase in CP55940-induced inhibition of forskolin-stimu...More data for this Ligand-Target Pair
Affinity DataEC50: 72nMAssay Description:Agonist activity at human CB1 receptor expressed in CHO cell membranes assessed as increase in G-protein coupling by measuring [35S]GTPgammaS binding...More data for this Ligand-Target Pair
Affinity DataEC50: 78nMAssay Description:Allosteric agonist activity at human CB1R expressed in CHO-K1 cells assessed as inhibition of forskolin-induced cAMP accumulation after 90 mins by hi...More data for this Ligand-Target Pair
Affinity DataEC50: 80nMAssay Description:Positive allosteric modulatory activity at human CB1R expressed in CHO-K1 cells assessed as increase in CP55940-induced inhibition of forskolin-stimu...More data for this Ligand-Target Pair
Affinity DataKi: 88nMAssay Description:Displacement of [3H]CP55940 from human CB1R receptor expressed in CHO cell membranes after 60 mins by liquid scintillation spectrometry analysisMore data for this Ligand-Target Pair
Affinity DataKi: 94nMAssay Description:Displacement of [3H]CP55940 from human CB1R receptor expressed in CHO cell membranes after 60 mins by liquid scintillation spectrometry analysisMore data for this Ligand-Target Pair
Affinity DataEC50: 110nMAssay Description:Positive allosteric modulatory activity at human CB1R expressed in CHO-K1 cells assessed as increase in CP55940-induced inhibition of forskolin-stimu...More data for this Ligand-Target Pair
Affinity DataKi: 110nMAssay Description:Displacement of [3H]CP55940 from human CB1R receptor expressed in CHO cell membranes after 60 mins by liquid scintillation spectrometry analysisMore data for this Ligand-Target Pair
Affinity DataKi: 120nMAssay Description:Displacement of [3H]CP55940 from human CB1R receptor expressed in CHO cell membranes after 60 mins by liquid scintillation spectrometry analysisMore data for this Ligand-Target Pair
Affinity DataEC50: 130nMAssay Description:Positive allosteric modulatory activity at human CB1R expressed in CHO-K1 cells assessed as increase in CP55940-induced inhibition of forskolin-stimu...More data for this Ligand-Target Pair
Affinity DataKi: 160nMAssay Description:Displacement of [3H]SR141716A from human CB1R receptor expressed in CHO cell membranes after 2 hrs by liquid scintillation spectrometry analysisMore data for this Ligand-Target Pair
Affinity DataEC50: 170nMAssay Description:Agonist activity at human CB1 receptor expressed in CHO cell membranes assessed as increase in G-protein coupling by measuring [35S]GTPgammaS binding...More data for this Ligand-Target Pair
Affinity DataEC50: 190nMAssay Description:Positive allosteric modulatory activity at human CB1R expressed in CHO-K1 cells assessed as increase in CP55940-induced beta arrestin2 recruitment af...More data for this Ligand-Target Pair
Affinity DataEC50: 191nMAssay Description:Positive allosteric modulatory activity at human CB1R expressed in CHO-K1 cells assessed as increase in CP55940-induced inhibition of forskolin-stimu...More data for this Ligand-Target Pair
Affinity DataEC50: 200nMAssay Description:Positive allosteric modulatory activity at human CB1R expressed in CHO-K1 cells assessed as increase in CP55940-induced beta arrestin2 recruitment af...More data for this Ligand-Target Pair
