Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) with all data for entry = 50010353
TargetLysosomal acid glucosylceramidase(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM20607((2-{4-[(1Z)-1,2-diphenylbut-1-en-1-yl]phenoxy}ethy...)
Affinity DataEC50:  2.50E+3nMAssay Description:Chaperone activity at GCase in wild-type human fibroblasts assessed as increase in GPN-induced reduction of calcium release using Fluo-8AM based fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50537911(CHEMBL4635139)
Affinity DataEC50:  1.10E+3nMAssay Description:Chaperone activity at GCase in wild-type human fibroblasts assessed as increase in GPN-induced reduction of calcium release using Fluo-8AM based fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50537912(CHEMBL4649463)
Affinity DataEC50:  700nMAssay Description:Chaperone activity at GCase in wild-type human fibroblasts assessed as increase in GPN-induced reduction of calcium release using Fluo-8AM based fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50537913(CHEMBL4647988)
Affinity DataEC50:  1.10E+3nMAssay Description:Chaperone activity at GCase in wild-type human fibroblasts assessed as increase in GPN-induced reduction of calcium release using Fluo-8AM based fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50537914(CHEMBL4636676)
Affinity DataEC50:  1.10E+3nMAssay Description:Chaperone activity at GCase in wild-type human fibroblasts assessed as increase in GPN-induced reduction of calcium release using Fluo-8AM based fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed