Compile Data Set for Download or QSAR
Report error Found 21 Enz. Inhib. hit(s) with all data for entry = 50010440
TargetPresenilin-1(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50538942(CHEMBL4645181)
Affinity DataIC50: 62nMAssay Description:Modulatory activity of gamma secretase in human SKNBE2 cells assessed as decrease in Abeta42 levels incubated for 6 hrs by sandwich ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50538943(CHEMBL4640097)
Affinity DataIC50: 91nMAssay Description:Modulatory activity of gamma secretase in human SKNBE2 cells assessed as decrease in Abeta42 levels incubated for 6 hrs by sandwich ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50538938(CHEMBL4641905)
Affinity DataIC50: 150nMAssay Description:Modulatory activity of gamma secretase in human SKNBE2 cells assessed as decrease in Abeta42 levels incubated for 6 hrs by sandwich ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50538937(CHEMBL4648092)
Affinity DataIC50: 170nMAssay Description:Modulatory activity of gamma secretase in human SKNBE2 cells assessed as decrease in Abeta42 levels incubated for 6 hrs by sandwich ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50538936(CHEMBL4635555)
Affinity DataIC50: 190nMAssay Description:Modulatory activity of gamma secretase in human SKNBE2 cells assessed as decrease in Abeta42 levels incubated for 6 hrs by sandwich ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50538939(CHEMBL4644422)
Affinity DataIC50: 240nMAssay Description:Modulatory activity of gamma secretase in human SKNBE2 cells assessed as decrease in Abeta42 levels incubated for 6 hrs by sandwich ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50538935(CHEMBL4632774)
Affinity DataIC50: 370nMAssay Description:Modulatory activity of gamma secretase in human SKNBE2 cells assessed as decrease in Abeta42 levels incubated for 6 hrs by sandwich ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50538941(CHEMBL4649432)
Affinity DataIC50: 390nMAssay Description:Modulatory activity of gamma secretase in human SKNBE2 cells assessed as decrease in Abeta42 levels incubated for 6 hrs by sandwich ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50538940(CHEMBL4638711)
Affinity DataIC50: 480nMAssay Description:Modulatory activity of gamma secretase in human SKNBE2 cells assessed as decrease in Abeta42 levels incubated for 6 hrs by sandwich ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50538924(CHEMBL4649486)
Affinity DataIC50: 580nMAssay Description:Modulatory activity of gamma secretase in human SKNBE2 cells assessed as decrease in Abeta42 levels incubated for 6 hrs by sandwich ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50538932(CHEMBL4647839)
Affinity DataIC50: 1.10E+3nMAssay Description:Modulatory activity of gamma secretase in human SKNBE2 cells assessed as decrease in Abeta42 levels incubated for 6 hrs by sandwich ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
LigandPNGBDBM50538923(CHEMBL4646768)
Affinity DataIC50: 2.00E+3nMAssay Description:Modulatory activity of gamma secretase in human SKNBE2 cells assessed as decrease in Abeta42 levels incubated for 6 hrs by sandwich ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50538931(CHEMBL4646122)
Affinity DataIC50: 4.50E+3nMAssay Description:Modulatory activity of gamma secretase in human SKNBE2 cells assessed as decrease in Abeta42 levels incubated for 6 hrs by sandwich ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50538927(CHEMBL4633072)
Affinity DataIC50: 4.50E+3nMAssay Description:Modulatory activity of gamma secretase in human SKNBE2 cells assessed as decrease in Abeta42 levels incubated for 6 hrs by sandwich ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50538934(CHEMBL4646019)
Affinity DataIC50: 5.10E+3nMAssay Description:Modulatory activity of gamma secretase in human SKNBE2 cells assessed as decrease in Abeta42 levels incubated for 6 hrs by sandwich ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50538930(CHEMBL4639345)
Affinity DataIC50: 6.20E+3nMAssay Description:Modulatory activity of gamma secretase in human SKNBE2 cells assessed as decrease in Abeta42 levels incubated for 6 hrs by sandwich ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50538928(CHEMBL4639625)
Affinity DataIC50: 7.20E+3nMAssay Description:Modulatory activity of gamma secretase in human SKNBE2 cells assessed as decrease in Abeta42 levels incubated for 6 hrs by sandwich ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50538929(CHEMBL4637276)
Affinity DataIC50: 9.40E+3nMAssay Description:Modulatory activity of gamma secretase in human SKNBE2 cells assessed as decrease in Abeta42 levels incubated for 6 hrs by sandwich ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50538933(CHEMBL4633646)
Affinity DataIC50: 1.00E+4nMAssay Description:Modulatory activity of gamma secretase in human SKNBE2 cells assessed as decrease in Abeta42 levels incubated for 6 hrs by sandwich ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50538926(CHEMBL4638416)
Affinity DataIC50: 5.00E+4nMAssay Description:Modulatory activity of gamma secretase in human SKNBE2 cells assessed as decrease in Abeta42 levels incubated for 6 hrs by sandwich ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50538925(CHEMBL4641697)
Affinity DataIC50: 5.00E+4nMAssay Description:Modulatory activity of gamma secretase in human SKNBE2 cells assessed as decrease in Abeta42 levels incubated for 6 hrs by sandwich ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed