Compile Data Set for Download or QSAR
Report error Found 10 Enz. Inhib. hit(s) with all data for entry = 50007444
TargetD(1A) dopamine receptor(Human)
Arrival Discovery

Curated by ChEMBL
LigandPNGBDBM435904(US10611751, Example 8 | 2-(2,6-dichlorophenyl)-1-(...)
Affinity DataEC50:  13nMAssay Description:Positive allosteric modulation of human D1 receptor expressed in HEK293 assessed as cAMP production incubated for 60 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
Arrival Discovery

Curated by ChEMBL
LigandPNGBDBM435739(US10611751, Example 1 | 2-(2,6-dichlorophenyl)-1-(...)
Affinity DataEC50:  16nMAssay Description:Positive allosteric modulation of human D1 receptor expressed in HEK293 assessed as cAMP production incubated for 60 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
Arrival Discovery

Curated by ChEMBL
LigandPNGBDBM50509507(CHEMBL4536851)
Affinity DataEC50:  18nMAssay Description:Positive allosteric modulation of human D1 receptor expressed in HEK293 assessed as cAMP production incubated for 60 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
Arrival Discovery

Curated by ChEMBL
LigandPNGBDBM435952(US10611751, Example 9 | 2-(2-chloro-6-fluorophenyl...)
Affinity DataEC50:  28nMAssay Description:Positive allosteric modulation of human D1 receptor expressed in HEK293 assessed as cAMP production incubated for 60 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
Arrival Discovery

Curated by ChEMBL
LigandPNGBDBM435897(US10611751, Example 7 | 2-(2-chlorophenyl)-1-((1S,...)
Affinity DataEC50:  81nMAssay Description:Positive allosteric modulation of human D1 receptor expressed in HEK293 assessed as cAMP production incubated for 60 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
Arrival Discovery

Curated by ChEMBL
LigandPNGBDBM436043(US10611751, Example 11 | 2-(2-chloro-5-fluoropheny...)
Affinity DataEC50:  112nMAssay Description:Positive allosteric modulation of human D1 receptor expressed in HEK293 assessed as cAMP production incubated for 60 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
Arrival Discovery

Curated by ChEMBL
LigandPNGBDBM435987(US10611751, Example 10 | 2-(2,6-difluorophenyl)-1-...)
Affinity DataEC50:  127nMAssay Description:Positive allosteric modulation of human D1 receptor expressed in HEK293 assessed as cAMP production incubated for 60 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
Arrival Discovery

Curated by ChEMBL
LigandPNGBDBM435762(US10611751, Example 2 | 2-(2,6-dichlorophenyl)-1- ...)
Affinity DataEC50:  172nMAssay Description:Positive allosteric modulation of human D1 receptor expressed in HEK293 assessed as cAMP production incubated for 60 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
Arrival Discovery

Curated by ChEMBL
LigandPNGBDBM435774(US10611751, Example 3 | 1-((1S,3R)-5-(1-cyclopropy...)
Affinity DataEC50:  287nMAssay Description:Positive allosteric modulation of human D1 receptor expressed in HEK293 assessed as cAMP production incubated for 60 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
Arrival Discovery

Curated by ChEMBL
LigandPNGBDBM436044(US10611751, Example 12 | 2-(2-chloro-4-fluoropheny...)
Affinity DataEC50:  540nMAssay Description:Positive allosteric modulation of human D1 receptor expressed in HEK293 assessed as cAMP production incubated for 60 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed