Compile Data Set for Download or QSAR
Report error Found 18 Enz. Inhib. hit(s) with all data for entry = 50007449
TargetEpithelial discoidin domain-containing receptor 1(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50509520(CHEMBL4539920)
Affinity DataIC50: 0.708nMAssay Description:Inhibition of FLAG-tagged DDR1 in human HEK293 cells assessed as reduction in collagen-1-induced DDR1 phosphorylation incubated for 18 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetEpithelial discoidin domain-containing receptor 1(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50509521(CHEMBL4439970)
Affinity DataIC50: 4nMAssay Description:Inhibition of kinase tracer 178 binding to recombinant human His-tagged DDR1 expressed in baculovirus infected Sf9 cells incubated for 1 hr by TR-FRE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetDiscoidin domain-containing receptor 2(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50509519(CHEMBL4546339)
Affinity DataIC50: 4.60nMAssay Description:Inhibition of kinase tracer 178 binding to recombinant human His-tagged DDR2 expressed in baculovirus infected Sf9 cells incubated for 1 hr by TR-FRE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetEpithelial discoidin domain-containing receptor 1(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50509520(CHEMBL4539920)
Affinity DataIC50: 4.70nMAssay Description:Inhibition of kinase tracer 178 binding to recombinant human His-tagged DDR1 expressed in baculovirus infected Sf9 cells incubated for 1 hr by TR-FRE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetEpithelial discoidin domain-containing receptor 1(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50297825(5-[(2-methyl-5-{[3-(trifluoromethyl)phenyl]carbamo...)
Affinity DataIC50: 4.80nMAssay Description:Inhibition of FLAG-tagged DDR1 in human HEK293 cells assessed as reduction in collagen-1-induced DDR1 phosphorylation incubated for 18 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetDiscoidin domain-containing receptor 2(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50509521(CHEMBL4439970)
Affinity DataIC50: 4.80nMAssay Description:Inhibition of kinase tracer 178 binding to recombinant human His-tagged DDR2 expressed in baculovirus infected Sf9 cells incubated for 1 hr by TR-FRE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetEpithelial discoidin domain-containing receptor 1(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50509522(CHEMBL4467377)
Affinity DataIC50: 5.90nMAssay Description:Inhibition of kinase tracer 178 binding to recombinant human His-tagged DDR1 expressed in baculovirus infected Sf9 cells incubated for 1 hr by TR-FRE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetDiscoidin domain-containing receptor 2(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50509522(CHEMBL4467377)
Affinity DataIC50: 6.40nMAssay Description:Inhibition of kinase tracer 178 binding to recombinant human His-tagged DDR2 expressed in baculovirus infected Sf9 cells incubated for 1 hr by TR-FRE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetDiscoidin domain-containing receptor 2(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50509520(CHEMBL4539920)
Affinity DataIC50: 7.40nMAssay Description:Inhibition of kinase tracer 178 binding to recombinant human His-tagged DDR2 expressed in baculovirus infected Sf9 cells incubated for 1 hr by TR-FRE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetEpithelial discoidin domain-containing receptor 1(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50509519(CHEMBL4546339)
Affinity DataIC50: 8.5nMAssay Description:Inhibition of kinase tracer 178 binding to recombinant human His-tagged DDR1 expressed in baculovirus infected Sf9 cells incubated for 1 hr by TR-FRE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetDiscoidin domain-containing receptor 2(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50509517(CHEMBL4447700)
Affinity DataIC50: 11nMAssay Description:Inhibition of kinase tracer 178 binding to recombinant human His-tagged DDR2 expressed in baculovirus infected Sf9 cells incubated for 1 hr by TR-FRE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetDiscoidin domain-containing receptor 2(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50509523(CHEMBL4584937)
Affinity DataIC50: 11nMAssay Description:Inhibition of kinase tracer 178 binding to recombinant human His-tagged DDR2 expressed in baculovirus infected Sf9 cells incubated for 1 hr by TR-FRE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetEpithelial discoidin domain-containing receptor 1(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50509517(CHEMBL4447700)
Affinity DataIC50: 11nMAssay Description:Inhibition of kinase tracer 178 binding to recombinant human His-tagged DDR1 expressed in baculovirus infected Sf9 cells incubated for 1 hr by TR-FRE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetEpithelial discoidin domain-containing receptor 1(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50297825(5-[(2-methyl-5-{[3-(trifluoromethyl)phenyl]carbamo...)
Affinity DataIC50: 12nMAssay Description:Inhibition of kinase tracer 178 binding to recombinant human GST-tagged DDR1 expressed in baculovirus expression system incubated for 60 mins by TR-F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetEpithelial discoidin domain-containing receptor 1(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50509523(CHEMBL4584937)
Affinity DataIC50: 15nMAssay Description:Inhibition of kinase tracer 178 binding to recombinant human His-tagged DDR1 expressed in baculovirus infected Sf9 cells incubated for 1 hr by TR-FRE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetDiscoidin domain-containing receptor 2(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50297825(5-[(2-methyl-5-{[3-(trifluoromethyl)phenyl]carbamo...)
Affinity DataIC50: 19nMAssay Description:Inhibition of kinase tracer 178 binding to recombinant human GST-tagged DDR2 (427-855 residues) expressed in baculovirus expression system incubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetEpithelial discoidin domain-containing receptor 1(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50509518(CHEMBL4483465)
Affinity DataIC50: 36nMAssay Description:Inhibition of kinase tracer 178 binding to recombinant human His-tagged DDR1 expressed in baculovirus infected Sf9 cells incubated for 1 hr by TR-FRE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetDiscoidin domain-containing receptor 2(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50509518(CHEMBL4483465)
Affinity DataIC50: 44nMAssay Description:Inhibition of kinase tracer 178 binding to recombinant human His-tagged DDR2 expressed in baculovirus infected Sf9 cells incubated for 1 hr by TR-FRE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed