Compile Data Set for Download or QSAR
Report error Found 62 Enz. Inhib. hit(s) with all data for entry = 50009310
TargetBile acid receptor(Human)
Genomics Institute of The Novartis Research Foundation (Gnf)

Curated by ChEMBL
LigandPNGBDBM50527040(LJN-452 | LJN452 | NVP-LJN452-NXA | Tropifexor)
Affinity DataEC50:  0.5nMAssay Description:Agonist activity at GST-tagged human FXR-LBD (193 to 472 residues) using biotinylated SRC-1 peptide as substrate incubated for 1 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetBile acid receptor(Human)
Genomics Institute of The Novartis Research Foundation (Gnf)

Curated by ChEMBL
LigandPNGBDBM50527040(LJN-452 | LJN452 | NVP-LJN452-NXA | Tropifexor)
Affinity DataEC50:  0.700nMAssay Description:Agonist activity at FXR transfected in human HEK293T cells o-expressing pGL3/hBSEP/luc incubated for 24 hrs by Steady-Glo reagent based luciferase re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetBile acid receptor(Human)
Genomics Institute of The Novartis Research Foundation (Gnf)

Curated by ChEMBL
LigandPNGBDBM50527042(CHEMBL4589802)
Affinity DataEC50:  6nMAssay Description:Agonist activity at FXR transfected in human HEK293T cells o-expressing pGL3/hBSEP/luc incubated for 24 hrs by Steady-Glo reagent based luciferase re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetBile acid receptor(Human)
Genomics Institute of The Novartis Research Foundation (Gnf)

Curated by ChEMBL
LigandPNGBDBM50527042(CHEMBL4589802)
Affinity DataEC50:  7nMAssay Description:Agonist activity at GST-tagged human FXR-LBD (193 to 472 residues) using biotinylated SRC-1 peptide as substrate incubated for 1 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetBile acid receptor(Human)
Genomics Institute of The Novartis Research Foundation (Gnf)

Curated by ChEMBL
LigandPNGBDBM50527021(Lmb763 | Nidufexor)
Affinity DataEC50:  7nMAssay Description:Agonist activity at GST-tagged human FXR-LBD (193 to 472 residues) using biotinylated SRC-1 peptide as substrate incubated for 1 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetBile acid receptor(Human)
Genomics Institute of The Novartis Research Foundation (Gnf)

Curated by ChEMBL
LigandPNGBDBM50527027(CHEMBL4452699)
Affinity DataEC50:  13nMAssay Description:Agonist activity at GST-tagged human FXR-LBD (193 to 472 residues) using biotinylated SRC-1 peptide as substrate incubated for 1 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetBile acid receptor(Human)
Genomics Institute of The Novartis Research Foundation (Gnf)

Curated by ChEMBL
LigandPNGBDBM50527034(CHEMBL4451515)
Affinity DataEC50:  16nMAssay Description:Agonist activity at GST-tagged human FXR-LBD (193 to 472 residues) using biotinylated SRC-1 peptide as substrate incubated for 1 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetBile acid receptor(Human)
Genomics Institute of The Novartis Research Foundation (Gnf)

Curated by ChEMBL
LigandPNGBDBM50527045(CHEMBL4553359)
Affinity DataEC50:  23nMAssay Description:Agonist activity at FXR transfected in human HEK293T cells o-expressing pGL3/hBSEP/luc incubated for 24 hrs by Steady-Glo reagent based luciferase re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetBile acid receptor(Human)
Genomics Institute of The Novartis Research Foundation (Gnf)

Curated by ChEMBL
LigandPNGBDBM50527023(CHEMBL4449035)
Affinity DataEC50:  24nMAssay Description:Agonist activity at GST-tagged human FXR-LBD (193 to 472 residues) using biotinylated SRC-1 peptide as substrate incubated for 1 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetBile acid receptor(Human)
Genomics Institute of The Novartis Research Foundation (Gnf)

Curated by ChEMBL
LigandPNGBDBM50527027(CHEMBL4452699)
Affinity DataEC50:  24nMAssay Description:Agonist activity at FXR transfected in human HEK293T cells o-expressing pGL3/hBSEP/luc incubated for 24 hrs by Steady-Glo reagent based luciferase re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetBile acid receptor(Human)
Genomics Institute of The Novartis Research Foundation (Gnf)

Curated by ChEMBL
LigandPNGBDBM50527035(CHEMBL4571319)
Affinity DataEC50:  25nMAssay Description:Agonist activity at GST-tagged human FXR-LBD (193 to 472 residues) using biotinylated SRC-1 peptide as substrate incubated for 1 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetBile acid receptor(Human)
Genomics Institute of The Novartis Research Foundation (Gnf)

Curated by ChEMBL
LigandPNGBDBM50527045(CHEMBL4553359)
Affinity DataEC50:  27nMAssay Description:Agonist activity at GST-tagged human FXR-LBD (193 to 472 residues) using biotinylated SRC-1 peptide as substrate incubated for 1 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetBile acid receptor(Human)
Genomics Institute of The Novartis Research Foundation (Gnf)

Curated by ChEMBL
LigandPNGBDBM50527021(Lmb763 | Nidufexor)
Affinity DataEC50:  32nMAssay Description:Agonist activity at FXR transfected in human HEK293T cells o-expressing pGL3/hBSEP/luc incubated for 24 hrs by Steady-Glo reagent based luciferase re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetBile acid receptor(Human)
Genomics Institute of The Novartis Research Foundation (Gnf)

Curated by ChEMBL
LigandPNGBDBM50527039(CHEMBL4472502)
Affinity DataEC50:  38nMAssay Description:Agonist activity at GST-tagged human FXR-LBD (193 to 472 residues) using biotinylated SRC-1 peptide as substrate incubated for 1 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetBile acid receptor(Human)
Genomics Institute of The Novartis Research Foundation (Gnf)

Curated by ChEMBL
LigandPNGBDBM50527034(CHEMBL4451515)
Affinity DataEC50:  39nMAssay Description:Agonist activity at FXR transfected in human HEK293T cells o-expressing pGL3/hBSEP/luc incubated for 24 hrs by Steady-Glo reagent based luciferase re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetBile acid receptor(Human)
Genomics Institute of The Novartis Research Foundation (Gnf)

Curated by ChEMBL
LigandPNGBDBM50527035(CHEMBL4571319)
Affinity DataEC50:  44nMAssay Description:Agonist activity at FXR transfected in human HEK293T cells o-expressing pGL3/hBSEP/luc incubated for 24 hrs by Steady-Glo reagent based luciferase re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetBile acid receptor(Human)
Genomics Institute of The Novartis Research Foundation (Gnf)

Curated by ChEMBL
LigandPNGBDBM50527023(CHEMBL4449035)
Affinity DataEC50:  46nMAssay Description:Agonist activity at FXR transfected in human HEK293T cells o-expressing pGL3/hBSEP/luc incubated for 24 hrs by Steady-Glo reagent based luciferase re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetBile acid receptor(Human)
Genomics Institute of The Novartis Research Foundation (Gnf)

Curated by ChEMBL
LigandPNGBDBM50527039(CHEMBL4472502)
Affinity DataEC50:  50nMAssay Description:Agonist activity at FXR transfected in human HEK293T cells o-expressing pGL3/hBSEP/luc incubated for 24 hrs by Steady-Glo reagent based luciferase re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetBile acid receptor(Human)
Genomics Institute of The Novartis Research Foundation (Gnf)

Curated by ChEMBL
LigandPNGBDBM50527024(CHEMBL4577381)
Affinity DataEC50:  71nMAssay Description:Agonist activity at GST-tagged human FXR-LBD (193 to 472 residues) using biotinylated SRC-1 peptide as substrate incubated for 1 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetBile acid receptor(Human)
Genomics Institute of The Novartis Research Foundation (Gnf)

Curated by ChEMBL
LigandPNGBDBM50527025(CHEMBL4519279)
Affinity DataEC50:  145nMAssay Description:Agonist activity at GST-tagged human FXR-LBD (193 to 472 residues) using biotinylated SRC-1 peptide as substrate incubated for 1 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetBile acid receptor(Human)
Genomics Institute of The Novartis Research Foundation (Gnf)

Curated by ChEMBL
LigandPNGBDBM50527029(CHEMBL4562405)
Affinity DataEC50:  150nMAssay Description:Agonist activity at FXR transfected in human HEK293T cells o-expressing pGL3/hBSEP/luc incubated for 24 hrs by Steady-Glo reagent based luciferase re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetBile acid receptor(Human)
Genomics Institute of The Novartis Research Foundation (Gnf)

Curated by ChEMBL
LigandPNGBDBM50527029(CHEMBL4562405)
Affinity DataEC50:  171nMAssay Description:Agonist activity at GST-tagged human FXR-LBD (193 to 472 residues) using biotinylated SRC-1 peptide as substrate incubated for 1 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetBile acid receptor(Human)
Genomics Institute of The Novartis Research Foundation (Gnf)

Curated by ChEMBL
LigandPNGBDBM50527024(CHEMBL4577381)
Affinity DataEC50:  186nMAssay Description:Agonist activity at FXR transfected in human HEK293T cells o-expressing pGL3/hBSEP/luc incubated for 24 hrs by Steady-Glo reagent based luciferase re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetBile acid receptor(Human)
Genomics Institute of The Novartis Research Foundation (Gnf)

Curated by ChEMBL
LigandPNGBDBM50527025(CHEMBL4519279)
Affinity DataEC50:  280nMAssay Description:Agonist activity at FXR transfected in human HEK293T cells o-expressing pGL3/hBSEP/luc incubated for 24 hrs by Steady-Glo reagent based luciferase re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetBile acid receptor(Human)
Genomics Institute of The Novartis Research Foundation (Gnf)

Curated by ChEMBL
LigandPNGBDBM50527041(CHEMBL4447977)
Affinity DataEC50:  480nMAssay Description:Agonist activity at GST-tagged human FXR-LBD (193 to 472 residues) using biotinylated SRC-1 peptide as substrate incubated for 1 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetBile acid receptor(Human)
Genomics Institute of The Novartis Research Foundation (Gnf)

Curated by ChEMBL
LigandPNGBDBM50527033(CHEMBL4514834)
Affinity DataEC50:  520nMAssay Description:Agonist activity at FXR transfected in human HEK293T cells o-expressing pGL3/hBSEP/luc incubated for 24 hrs by Steady-Glo reagent based luciferase re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetBile acid receptor(Human)
Genomics Institute of The Novartis Research Foundation (Gnf)

Curated by ChEMBL
LigandPNGBDBM50527033(CHEMBL4514834)
Affinity DataEC50:  530nMAssay Description:Agonist activity at GST-tagged human FXR-LBD (193 to 472 residues) using biotinylated SRC-1 peptide as substrate incubated for 1 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetBile acid receptor(Human)
Genomics Institute of The Novartis Research Foundation (Gnf)

Curated by ChEMBL
LigandPNGBDBM50527041(CHEMBL4447977)
Affinity DataEC50:  690nMAssay Description:Agonist activity at FXR transfected in human HEK293T cells o-expressing pGL3/hBSEP/luc incubated for 24 hrs by Steady-Glo reagent based luciferase re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetBile acid receptor(Human)
Genomics Institute of The Novartis Research Foundation (Gnf)

Curated by ChEMBL
LigandPNGBDBM50527028(CHEMBL4441366)
Affinity DataEC50:  2.17E+3nMAssay Description:Agonist activity at FXR transfected in human HEK293T cells o-expressing pGL3/hBSEP/luc incubated for 24 hrs by Steady-Glo reagent based luciferase re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetBile acid receptor(Human)
Genomics Institute of The Novartis Research Foundation (Gnf)

Curated by ChEMBL
LigandPNGBDBM50527030(CHEMBL4473498)
Affinity DataEC50:  2.70E+3nMAssay Description:Agonist activity at FXR transfected in human HEK293T cells o-expressing pGL3/hBSEP/luc incubated for 24 hrs by Steady-Glo reagent based luciferase re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetBile acid receptor(Human)
Genomics Institute of The Novartis Research Foundation (Gnf)

Curated by ChEMBL
LigandPNGBDBM50527026(CHEMBL4559492)
Affinity DataEC50:  2.84E+3nMAssay Description:Agonist activity at GST-tagged human FXR-LBD (193 to 472 residues) using biotinylated SRC-1 peptide as substrate incubated for 1 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetBile acid receptor(Human)
Genomics Institute of The Novartis Research Foundation (Gnf)

Curated by ChEMBL
LigandPNGBDBM50527044(CHEMBL4483715)
Affinity DataEC50:  4.30E+3nMAssay Description:Agonist activity at FXR transfected in human HEK293T cells o-expressing pGL3/hBSEP/luc incubated for 24 hrs by Steady-Glo reagent based luciferase re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetBile acid receptor(Human)
Genomics Institute of The Novartis Research Foundation (Gnf)

Curated by ChEMBL
LigandPNGBDBM50527028(CHEMBL4441366)
Affinity DataEC50:  4.80E+3nMAssay Description:Agonist activity at GST-tagged human FXR-LBD (193 to 472 residues) using biotinylated SRC-1 peptide as substrate incubated for 1 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetBile acid receptor(Human)
Genomics Institute of The Novartis Research Foundation (Gnf)

Curated by ChEMBL
LigandPNGBDBM50527026(CHEMBL4559492)
Affinity DataEC50:  4.84E+3nMAssay Description:Agonist activity at FXR transfected in human HEK293T cells o-expressing pGL3/hBSEP/luc incubated for 24 hrs by Steady-Glo reagent based luciferase re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetBile acid receptor(Human)
Genomics Institute of The Novartis Research Foundation (Gnf)

Curated by ChEMBL
LigandPNGBDBM50527030(CHEMBL4473498)
Affinity DataEC50:  6.00E+3nMAssay Description:Agonist activity at GST-tagged human FXR-LBD (193 to 472 residues) using biotinylated SRC-1 peptide as substrate incubated for 1 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetBile acid receptor(Human)
Genomics Institute of The Novartis Research Foundation (Gnf)

Curated by ChEMBL
LigandPNGBDBM50527022(CHEMBL4590255)
Affinity DataEC50:  6.00E+3nMAssay Description:Agonist activity at GST-tagged human FXR-LBD (193 to 472 residues) using biotinylated SRC-1 peptide as substrate incubated for 1 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetBile acid receptor(Human)
Genomics Institute of The Novartis Research Foundation (Gnf)

Curated by ChEMBL
LigandPNGBDBM50527037(CHEMBL4516937)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at GST-tagged human FXR-LBD (193 to 472 residues) using biotinylated SRC-1 peptide as substrate incubated for 1 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetBile acid receptor(Human)
Genomics Institute of The Novartis Research Foundation (Gnf)

Curated by ChEMBL
LigandPNGBDBM50527038(CHEMBL4470523)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at GST-tagged human FXR-LBD (193 to 472 residues) using biotinylated SRC-1 peptide as substrate incubated for 1 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetBile acid receptor(Human)
Genomics Institute of The Novartis Research Foundation (Gnf)

Curated by ChEMBL
LigandPNGBDBM50527036(CHEMBL4436049)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at GST-tagged human FXR-LBD (193 to 472 residues) using biotinylated SRC-1 peptide as substrate incubated for 1 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetBile acid receptor(Human)
Genomics Institute of The Novartis Research Foundation (Gnf)

Curated by ChEMBL
LigandPNGBDBM50527044(CHEMBL4483715)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at GST-tagged human FXR-LBD (193 to 472 residues) using biotinylated SRC-1 peptide as substrate incubated for 1 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetBile acid receptor(Human)
Genomics Institute of The Novartis Research Foundation (Gnf)

Curated by ChEMBL
LigandPNGBDBM50527032(CHEMBL4465272)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at GST-tagged human FXR-LBD (193 to 472 residues) using biotinylated SRC-1 peptide as substrate incubated for 1 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetBile acid receptor(Human)
Genomics Institute of The Novartis Research Foundation (Gnf)

Curated by ChEMBL
LigandPNGBDBM50527031(CHEMBL4524552)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at GST-tagged human FXR-LBD (193 to 472 residues) using biotinylated SRC-1 peptide as substrate incubated for 1 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Genomics Institute of The Novartis Research Foundation (Gnf)

Curated by ChEMBL
LigandPNGBDBM50527021(Lmb763 | Nidufexor)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at GAL4-fused Glucocorticoid receptor (unknown origin) expressed in HEK293T cells incubated for 24 by BrightGlo reagent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Genomics Institute of The Novartis Research Foundation (Gnf)

Curated by ChEMBL
LigandPNGBDBM50527021(Lmb763 | Nidufexor)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at GAL4-fused ERalpha (unknown origin) expressed in HEK293T cells incubated for 24 by BrightGlo reagent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetRetinoic acid receptor RXR-alpha(Human)
Genomics Institute of The Novartis Research Foundation (Gnf)

Curated by ChEMBL
LigandPNGBDBM50527021(Lmb763 | Nidufexor)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at GAL4-fused RXR LBD (unknown origin) expressed in HEK293T cells incubated for 24 by BrightGlo reagent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetBile acid receptor(Human)
Genomics Institute of The Novartis Research Foundation (Gnf)

Curated by ChEMBL
LigandPNGBDBM50527032(CHEMBL4465272)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at FXR transfected in human HEK293T cells o-expressing pGL3/hBSEP/luc incubated for 24 hrs by Steady-Glo reagent based luciferase re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetBile acid receptor(Human)
Genomics Institute of The Novartis Research Foundation (Gnf)

Curated by ChEMBL
LigandPNGBDBM50527043(CHEMBL4527188)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at GST-tagged human FXR-LBD (193 to 472 residues) using biotinylated SRC-1 peptide as substrate incubated for 1 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Genomics Institute of The Novartis Research Foundation (Gnf)

Curated by ChEMBL
LigandPNGBDBM50527021(Lmb763 | Nidufexor)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at GAL4-fused PPARgamma (unknown origin) expressed in HEK293T cells incubated for 24 by BrightGlo reagent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetBile acid receptor(Human)
Genomics Institute of The Novartis Research Foundation (Gnf)

Curated by ChEMBL
LigandPNGBDBM50527038(CHEMBL4470523)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at FXR transfected in human HEK293T cells o-expressing pGL3/hBSEP/luc incubated for 24 hrs by Steady-Glo reagent based luciferase re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetBile acid receptor(Human)
Genomics Institute of The Novartis Research Foundation (Gnf)

Curated by ChEMBL
LigandPNGBDBM50527031(CHEMBL4524552)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at FXR transfected in human HEK293T cells o-expressing pGL3/hBSEP/luc incubated for 24 hrs by Steady-Glo reagent based luciferase re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
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