Compile Data Set for Download or QSAR
Report error Found 89 Enz. Inhib. hit(s) with all data for entry = 50008563
TargetNicotinic acetylcholine receptor alpha9/alpha10(Rat)
Hainan University

Curated by ChEMBL
LigandPNGBDBM50520487(CHEMBL4553407)
Affinity DataIC50: 5nMAssay Description:Antagonist activity at rat alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response at -70 mV holding p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetNicotinic acetylcholine receptor alpha9/alpha10(Rat)
Hainan University

Curated by ChEMBL
LigandPNGBDBM50520481(CHEMBL4446775)
Affinity DataIC50: 5nMAssay Description:Antagonist activity at rat alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response at -70 mV holding p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetNicotinic acetylcholine receptor alpha9/alpha10(Rat)
Hainan University

Curated by ChEMBL
LigandPNGBDBM50520495(CHEMBL4534950)
Affinity DataIC50: 5nMAssay Description:Antagonist activity at rat alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response at -70 mV holding p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetNicotinic acetylcholine receptor alpha9/alpha10(Rat)
Hainan University

Curated by ChEMBL
LigandPNGBDBM50520487(CHEMBL4553407)
Affinity DataIC50: 5nMAssay Description:Antagonist activity at rat alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response at -70 mV holding p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetNicotinic acetylcholine receptor alpha9/alpha10(Rat)
Hainan University

Curated by ChEMBL
LigandPNGBDBM50520486(CHEMBL4460411)
Affinity DataIC50: 6.10nMAssay Description:Antagonist activity at rat alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response at -70 mV holding p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetNicotinic acetylcholine receptor alpha9/alpha10(Rat)
Hainan University

Curated by ChEMBL
LigandPNGBDBM50520480(CHEMBL4450578)
Affinity DataIC50: 11nMAssay Description:Antagonist activity at rat alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response at -70 mV holding p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetNicotinic acetylcholine receptor alpha9/alpha10(Rat)
Hainan University

Curated by ChEMBL
LigandPNGBDBM50520491(CHEMBL4525995)
Affinity DataIC50: 12nMAssay Description:Antagonist activity at rat alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response at -70 mV holding p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetNicotinic acetylcholine receptor alpha9/alpha10(Rat)
Hainan University

Curated by ChEMBL
LigandPNGBDBM50520477(CHEMBL4460879)
Affinity DataIC50: 12nMAssay Description:Antagonist activity at rat alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response at -70 mV holding p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetNicotinic acetylcholine receptor alpha9/alpha10(Rat)
Hainan University

Curated by ChEMBL
LigandPNGBDBM50520477(CHEMBL4460879)
Affinity DataIC50: 12nMAssay Description:Antagonist activity at rat alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response at -70 mV holding p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetNicotinic acetylcholine receptor alpha9/alpha10(Rat)
Hainan University

Curated by ChEMBL
LigandPNGBDBM50520492(CHEMBL4554920)
Affinity DataIC50: 13nMAssay Description:Antagonist activity at rat alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response at -70 mV holding p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetNicotinic acetylcholine receptor alpha9/alpha10(Rat)
Hainan University

Curated by ChEMBL
LigandPNGBDBM50520494(CHEMBL4540592)
Affinity DataIC50: 13nMAssay Description:Antagonist activity at rat alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response at -70 mV holding p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetNicotinic acetylcholine receptor alpha9/alpha10(Rat)
Hainan University

Curated by ChEMBL
LigandPNGBDBM50520476(CHEMBL4463717)
Affinity DataIC50: 14nMAssay Description:Antagonist activity at rat alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response at -70 mV holding p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetNicotinic acetylcholine receptor alpha9/alpha10(Rat)
Hainan University

Curated by ChEMBL
LigandPNGBDBM50520490(CHEMBL4522506)
Affinity DataIC50: 14nMAssay Description:Antagonist activity at rat alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response at -70 mV holding p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetNicotinic acetylcholine receptor alpha9/alpha10(Rat)
Hainan University

Curated by ChEMBL
LigandPNGBDBM50520488(CHEMBL4448288)
Affinity DataIC50: 16nMAssay Description:Antagonist activity at rat alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response at -70 mV holding p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetNicotinic acetylcholine receptor alpha9/alpha10(Rat)
Hainan University

Curated by ChEMBL
LigandPNGBDBM50520493(CHEMBL4577696)
Affinity DataIC50: 17nMAssay Description:Antagonist activity at rat alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response at -70 mV holding p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetNicotinic acetylcholine receptor alpha9/alpha10(Rat)
Hainan University

Curated by ChEMBL
LigandPNGBDBM50520489(CHEMBL4455583)
Affinity DataIC50: 21nMAssay Description:Antagonist activity at rat alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response at -70 mV holding p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
Hainan University

Curated by ChEMBL
LigandPNGBDBM50520486(CHEMBL4460411)
Affinity DataIC50: 33nMAssay Description:Antagonist activity at human alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response at -70 mV holding...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetNicotinic acetylcholine receptor alpha9/alpha10(Rat)
Hainan University

Curated by ChEMBL
LigandPNGBDBM50520479(CHEMBL4473421)
Affinity DataIC50: 36nMAssay Description:Antagonist activity at rat alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response at -70 mV holding p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
Hainan University

Curated by ChEMBL
LigandPNGBDBM50520477(CHEMBL4460879)
Affinity DataIC50: 52nMAssay Description:Antagonist activity at human alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response at -70 mV holding...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetSodium channel protein type 4 subunit alpha(Rat)
Hainan University

Curated by ChEMBL
LigandPNGBDBM50520482(CHEMBL4562161)
Affinity DataIC50: 69nMAssay Description:Inhibition of rat Nav1.4 expressed in HEK293 cells at -80 mV holding potential by whole cell patch-clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetSodium channel protein type 3 subunit alpha(Human)
Hainan University

Curated by ChEMBL
LigandPNGBDBM50520478(CHEMBL4436427)
Affinity DataIC50: 110nMAssay Description:Inhibition of Nav1.3 (unknown origin) expressed in Xenopus laevis oocytes at -80 mV holding potential by two electrode voltage-clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetSodium channel protein type 3 subunit alpha(Human)
Hainan University

Curated by ChEMBL
LigandPNGBDBM50520499(CHEMBL4517378)
Affinity DataIC50: 200nMAssay Description:Inhibition of Nav1.3 (unknown origin) expressed in Xenopus laevis oocytes at -80 mV holding potential by two electrode voltage-clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetSodium channel protein type 3 subunit alpha(Human)
Hainan University

Curated by ChEMBL
LigandPNGBDBM50520496(CHEMBL4469517)
Affinity DataIC50: 260nMAssay Description:Inhibition of Nav1.3 (unknown origin) expressed in Xenopus laevis oocytes at -80 mV holding potential by two electrode voltage-clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
LigandPNGBDBM50520487(CHEMBL4553407)
Affinity DataIC50: 440nMAssay Description:Antagonist activity at rat alpha2beta2 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response at -70 mV holding pot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Hainan University

Curated by ChEMBL
LigandPNGBDBM50445329(CHEMBL3104242)
Affinity DataIC50: 497nMAssay Description:Antagonist activity at human alpha7 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response at -80 mV holding potent...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Hainan University

Curated by ChEMBL
LigandPNGBDBM50520477(CHEMBL4460879)
Affinity DataIC50: 660nMAssay Description:Antagonist activity at rat alpha7 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response at -70 mV holding potentia...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
LigandPNGBDBM50520477(CHEMBL4460879)
Affinity DataIC50: 940nMAssay Description:Antagonist activity at rat alpha3beta2 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response at -70 mV holding pot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
LigandPNGBDBM50520479(CHEMBL4473421)
Affinity DataIC50: 1.05E+3nMAssay Description:Antagonist activity at rat alpha3beta2 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response at -70 mV holding pot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Hainan University

Curated by ChEMBL
LigandPNGBDBM50520480(CHEMBL4450578)
Affinity DataIC50: 1.08E+3nMAssay Description:Antagonist activity at rat alpha7 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response at -70 mV holding potentia...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
LigandPNGBDBM50520492(CHEMBL4554920)
Affinity DataIC50: 1.18E+3nMAssay Description:Antagonist activity at rat alpha3beta2 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response at -70 mV holding pot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
LigandPNGBDBM50520487(CHEMBL4553407)
Affinity DataIC50: 1.25E+3nMAssay Description:Antagonist activity at rat alpha3beta2 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response at -70 mV holding pot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Hainan University

Curated by ChEMBL
LigandPNGBDBM50520486(CHEMBL4460411)
Affinity DataIC50: 1.27E+3nMAssay Description:Antagonist activity at rat alpha7 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response at -70 mV holding potentia...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
LigandPNGBDBM50520493(CHEMBL4577696)
Affinity DataIC50: 1.37E+3nMAssay Description:Antagonist activity at rat alpha3beta2 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response at -70 mV holding pot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Hainan University

Curated by ChEMBL
LigandPNGBDBM50520490(CHEMBL4522506)
Affinity DataIC50: 1.40E+3nMAssay Description:Antagonist activity at rat alpha7 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response at -70 mV holding potentia...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Hainan University

Curated by ChEMBL
LigandPNGBDBM50520492(CHEMBL4554920)
Affinity DataIC50: 1.51E+3nMAssay Description:Antagonist activity at rat alpha7 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response at -70 mV holding potentia...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Hainan University

Curated by ChEMBL
LigandPNGBDBM50520491(CHEMBL4525995)
Affinity DataIC50: 1.52E+3nMAssay Description:Antagonist activity at rat alpha7 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response at -70 mV holding potentia...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
LigandPNGBDBM50520489(CHEMBL4455583)
Affinity DataIC50: 1.57E+3nMAssay Description:Antagonist activity at rat alpha3beta2 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response at -70 mV holding pot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
LigandPNGBDBM50520477(CHEMBL4460879)
Affinity DataIC50: 1.61E+3nMAssay Description:Antagonist activity at rat alpha2beta2 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response at -70 mV holding pot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Hainan University

Curated by ChEMBL
LigandPNGBDBM50520488(CHEMBL4448288)
Affinity DataIC50: 1.69E+3nMAssay Description:Antagonist activity at rat alpha7 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response at -70 mV holding potentia...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Hainan University

Curated by ChEMBL
LigandPNGBDBM50520481(CHEMBL4446775)
Affinity DataIC50: 1.71E+3nMAssay Description:Antagonist activity at rat alpha7 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response at -70 mV holding potentia...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
LigandPNGBDBM50520488(CHEMBL4448288)
Affinity DataIC50: 2.09E+3nMAssay Description:Antagonist activity at rat alpha3beta2 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response at -70 mV holding pot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetSodium channel protein type 4 subunit alpha(Rat)
Hainan University

Curated by ChEMBL
LigandPNGBDBM50520483(CHEMBL4524508)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of rat Nav1.4 expressed in HEK293 cells at -80 mV holding potential by whole cell patch-clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
LigandPNGBDBM50520492(CHEMBL4554920)
Affinity DataIC50: 2.16E+3nMAssay Description:Antagonist activity at rat alpha2beta2 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response at -70 mV holding pot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
LigandPNGBDBM50520489(CHEMBL4455583)
Affinity DataIC50: 2.23E+3nMAssay Description:Antagonist activity at rat alpha2beta2 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response at -70 mV holding pot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
LigandPNGBDBM50520480(CHEMBL4450578)
Affinity DataIC50: 2.78E+3nMAssay Description:Antagonist activity at rat alpha3beta2 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response at -70 mV holding pot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Hainan University

Curated by ChEMBL
LigandPNGBDBM50520487(CHEMBL4553407)
Affinity DataIC50: 2.83E+3nMAssay Description:Antagonist activity at rat alpha7 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response at -70 mV holding potentia...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
LigandPNGBDBM50520486(CHEMBL4460411)
Affinity DataIC50: 2.83E+3nMAssay Description:Antagonist activity at rat alpha3beta2 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response at -70 mV holding pot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
LigandPNGBDBM50520493(CHEMBL4577696)
Affinity DataIC50: 2.99E+3nMAssay Description:Antagonist activity at rat alpha2beta2 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response at -70 mV holding pot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Hainan University

Curated by ChEMBL
LigandPNGBDBM50520489(CHEMBL4455583)
Affinity DataIC50: 3.02E+3nMAssay Description:Antagonist activity at rat alpha7 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response at -70 mV holding potentia...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
LigandPNGBDBM50520490(CHEMBL4522506)
Affinity DataIC50: 3.12E+3nMAssay Description:Antagonist activity at rat alpha2beta2 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response at -70 mV holding pot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
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