Compile Data Set for Download or QSAR
Report error Found 23 Enz. Inhib. hit(s) with all data for entry = 50011158
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50545382(CHEMBL4646450)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of human CDK4/cyclin-D1 using RB protein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50545379(CHEMBL4645010)
Affinity DataIC50: 5nMAssay Description:Inhibition of human CDK4/cyclin-D1 using RB protein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50545380(CHEMBL4645458)
Affinity DataIC50: 6.30nMAssay Description:Inhibition of human CDK4/cyclin-D1 using RB protein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50545383(CHEMBL4636355)
Affinity DataIC50: 6.30nMAssay Description:Inhibition of human CDK4/cyclin-D1 using RB protein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D3(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50545382(CHEMBL4646450)
Affinity DataIC50: 7.90nMAssay Description:Inhibition of human CDK6/cyclin-D3 using RB protein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM6309(8-cyclopentyl-6-acetyl-5-methyl-2-{[5-(piperazin-1...)
Affinity DataIC50: 10nMAssay Description:Inhibition of human CDK4/cyclin-D1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D3(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50545379(CHEMBL4645010)
Affinity DataIC50: 13nMAssay Description:Inhibition of human CDK6/cyclin-D3 using RB protein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetG1/S-specific cyclin-D2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM6309(8-cyclopentyl-6-acetyl-5-methyl-2-{[5-(piperazin-1...)
Affinity DataIC50: 16nMAssay Description:Inhibition of human CDK6/cyclin-D2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D3(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50545383(CHEMBL4636355)
Affinity DataIC50: 16nMAssay Description:Inhibition of human CDK6/cyclin-D3 using RB protein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50545381(CHEMBL4649032)
Affinity DataIC50: 16nMAssay Description:Inhibition of human CDK4/cyclin-D1 using RB protein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D3(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50545380(CHEMBL4645458)
Affinity DataIC50: 16nMAssay Description:Inhibition of human CDK6/cyclin-D3 using RB protein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50545384(CHEMBL4548417)
Affinity DataIC50: 20nMAssay Description:Inhibition of human CDK4/cyclin-D1 using RB protein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50545376(CHEMBL4638166)
Affinity DataIC50: 32nMAssay Description:Inhibition of human CDK4/cyclin-D1 using RB protein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50545378(CHEMBL4638298)
Affinity DataIC50: 32nMAssay Description:Inhibition of human CDK4/cyclin-D1 using RB protein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM6309(8-cyclopentyl-6-acetyl-5-methyl-2-{[5-(piperazin-1...)
Affinity DataIC50: 32nMAssay Description:Inhibition of human CDK4/cyclin-D1 using RB protein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D3(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50545381(CHEMBL4649032)
Affinity DataIC50: 40nMAssay Description:Inhibition of human CDK6/cyclin-D3 using RB protein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50545377(CHEMBL4640158)
Affinity DataIC50: 40nMAssay Description:Inhibition of human CDK4/cyclin-D1 using RB protein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D3(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50545384(CHEMBL4548417)
Affinity DataIC50: 50nMAssay Description:Inhibition of human CDK6/cyclin-D3 using RB protein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D3(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM6309(8-cyclopentyl-6-acetyl-5-methyl-2-{[5-(piperazin-1...)
Affinity DataIC50: 100nMAssay Description:Inhibition of human CDK6/cyclin-D3 using RB protein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D3(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50545378(CHEMBL4638298)
Affinity DataIC50: 126nMAssay Description:Inhibition of human CDK6/cyclin-D3 using RB protein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D3(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50545377(CHEMBL4640158)
Affinity DataIC50: 158nMAssay Description:Inhibition of human CDK6/cyclin-D3 using RB protein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D3(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50545376(CHEMBL4638166)
Affinity DataIC50: 200nMAssay Description:Inhibition of human CDK6/cyclin-D3 using RB protein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D3(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50545376(CHEMBL4638166)
Affinity DataIC50: 200nMAssay Description:Inhibition of human CDK6/cyclin-D3 using RB protein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed