Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) with all data for entry = 50010406
TargetRap guanine nucleotide exchange factor 3(Human)
University of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50511917(CHEMBL4534834)
Affinity DataKd:  6.60E+3nMAssay Description:Binding affinity to GST-tagged human EPAC1 CNBD (149 to 318 residues) expressed in Escherichia coli BL21 (DE3) incubated for 30 mins by 8-NBD-cAMP ba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetRap guanine nucleotide exchange factor 3(Human)
University of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50384264(CHEMBL316966)
Affinity DataKd:  4.50E+3nMAssay Description:Binding affinity to GST-tagged human EPAC1 CNBD (149 to 318 residues) expressed in Escherichia coli BL21 (DE3) incubated for 30 mins by 8-NBD-cAMP ba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetRap guanine nucleotide exchange factor 3(Human)
University of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50511917(CHEMBL4534834)
Affinity DataKd:  4.90E+3nMAssay Description:Binding affinity to GST-tagged human EPAC1 L273W mutant expressed in Escherichia coli BL21 (DE3) incubated for 30 mins by 8-NBD-cAMP based competitiv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed