Compile Data Set for Download or QSAR
Report error Found 325 Enz. Inhib. hit(s) with all data for entry = 50009368
TargetD(3) dopamine receptor(Human)
National Institute of Neurological Disorders and Stroke

Curated by ChEMBL
LigandPNGBDBM50527972(CHEMBL4476784 | US11634404, Compound 1)
Affinity DataEC50:  0.180nMAssay Description:Agonist activity at RLuc8-fused Go-coupled human D3R expressed in HEK293 cells untagged beta1 and mVenus-tagged gamma2 measured after 5 mins in prese...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
National Institute of Neurological Disorders and Stroke

Curated by ChEMBL
LigandPNGBDBM50116766((6S)-N(6)-propyl-4,5,6,7-tetrahydro-1,3-benzothiaz...)
Affinity DataKi:  0.900nMAssay Description:Displacement of [3H]-N-methylspiperone from D3 receptor (unknown origin) measured after 90 mins by microbeta scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetD(3) dopamine receptor(Human)
National Institute of Neurological Disorders and Stroke

Curated by ChEMBL
LigandPNGBDBM50116766((6S)-N(6)-propyl-4,5,6,7-tetrahydro-1,3-benzothiaz...)
Affinity DataKi:  0.940nMAssay Description:Displacement of [3H]-7-OH-DPAT from human D3R expressed in HEK293 cell membranes measured after 90 mins in Tris buffer by topcount assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetD(3) dopamine receptor(Human)
National Institute of Neurological Disorders and Stroke

Curated by ChEMBL
LigandPNGBDBM55121(cid_65340 | Dopamine | SMR000059081 | 4-(2-aminoet...)
Affinity DataEC50:  1.10nMAssay Description:Agonist activity at RLuc8-fused Go-coupled human D3R expressed in HEK293 cells untagged beta1 and mVenus-tagged gamma2 measured after 5 mins in prese...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
National Institute of Neurological Disorders and Stroke

Curated by ChEMBL
LigandPNGBDBM50116766((6S)-N(6)-propyl-4,5,6,7-tetrahydro-1,3-benzothiaz...)
Affinity DataKi:  1.10nMAssay Description:Displacement of [3H]-7-OH-DPAT from human D3R expressed in HEK293 cell membranes measured after 90 mins in EBSS buffer by topcount assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetD(3) dopamine receptor(Human)
National Institute of Neurological Disorders and Stroke

Curated by ChEMBL
LigandPNGBDBM50527972(CHEMBL4476784 | US11634404, Compound 1)
Affinity DataEC50:  1.20nMAssay Description:Agonist activity at RLuc8-fused human D3R expressed in HEK293 cells co-expressing N-terminal Venus-tagged beta-arrestin2 and GRK3 assessed as inducti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
National Institute of Neurological Disorders and Stroke

Curated by ChEMBL
LigandPNGBDBM55121(cid_65340 | Dopamine | SMR000059081 | 4-(2-aminoet...)
Affinity DataEC50:  2.30nMAssay Description:Agonist activity at RLuc8-fused human D3R expressed in HEK293 cells co-expressing N-terminal Venus-tagged beta-arrestin2 and GRK3 assessed as inducti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
National Institute of Neurological Disorders and Stroke

Curated by ChEMBL
LigandPNGBDBM55121(cid_65340 | Dopamine | SMR000059081 | 4-(2-aminoet...)
Affinity DataEC50:  2.90nMAssay Description:Agonist activity at human D3R stably expressed in CHOK1 cells assessed as increase in ERK1/2 phosphorylation measured after 15 mins by AlphaScreen su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
National Institute of Neurological Disorders and Stroke

Curated by ChEMBL
LigandPNGBDBM50528020(CHEMBL4455456 | US11634404, Compound 78)
Affinity DataEC50:  3nMAssay Description:Agonist activity at human D3R expressed in CHOK1 cells assessed as induction of beta-arrestin recruitment measured after 90 mins by beta-galactosidas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
National Institute of Neurological Disorders and Stroke

Curated by ChEMBL
LigandPNGBDBM55121(cid_65340 | Dopamine | SMR000059081 | 4-(2-aminoet...)
Affinity DataEC50:  3.5nMAssay Description:Agonist activity at human D3R expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP production measured after 5 mins in prese...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
National Institute of Neurological Disorders and Stroke

Curated by ChEMBL
LigandPNGBDBM50528069(CHEMBL4459426 | US11634404, Compound 20)
Affinity DataEC50:  4.30nMAssay Description:Agonist activity at human D3R expressed in CHOK1 cells assessed as induction of beta-arrestin recruitment measured after 90 mins by beta-galactosidas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
National Institute of Neurological Disorders and Stroke

Curated by ChEMBL
LigandPNGBDBM50527973(CHEMBL4472628 | US11634404, Compound 80)
Affinity DataEC50:  4.40nMAssay Description:Agonist activity at human D3R expressed in CHOK1 cells assessed as induction of beta-arrestin recruitment measured after 90 mins by beta-galactosidas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
National Institute of Neurological Disorders and Stroke

Curated by ChEMBL
LigandPNGBDBM10755([3H]-5-HT | 5-Hydroxy Tryptamine | 2-imino-1-methy...)
Affinity DataEC50:  4.5nMAssay Description:Agonist activity at recombinant human 5-HT2B receptor expressed in CHOK1 cells assessed as increase in inositol1-phosphate accumulation measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
National Institute of Neurological Disorders and Stroke

Curated by ChEMBL
LigandPNGBDBM50116766((6S)-N(6)-propyl-4,5,6,7-tetrahydro-1,3-benzothiaz...)
Affinity DataKi:  4.70nMAssay Description:Displacement of [3H]-methylspiperon from human D2RL expressed in HEK293 cell membranes measured after 90 mins by topcount assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
National Institute of Neurological Disorders and Stroke

Curated by ChEMBL
LigandPNGBDBM50527999(CHEMBL4554045 | US11634404, Compound 108)
Affinity DataEC50:  5nMAssay Description:Agonist activity at human D3R expressed in CHOK1 cells assessed as induction of beta-arrestin recruitment measured after 90 mins by beta-galactosidas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
National Institute of Neurological Disorders and Stroke

Curated by ChEMBL
LigandPNGBDBM50116766((6S)-N(6)-propyl-4,5,6,7-tetrahydro-1,3-benzothiaz...)
Affinity DataEC50:  5.40nMAssay Description:Agonist activity at human D3R expressed in CHOK1 cells assessed as induction of beta-arrestin recruitment measured after 90 mins by beta-galactosidas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetD(3) dopamine receptor(Human)
National Institute of Neurological Disorders and Stroke

Curated by ChEMBL
LigandPNGBDBM50400511(CHEMBL2203406)
Affinity DataKi:  5.60nMAssay Description:Displacement of [3H]-methylspiperon from human D3R expressed in HEK293 cell membranes measured after 90 mins in EBSS buffer by topcount assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
National Institute of Neurological Disorders and Stroke

Curated by ChEMBL
LigandPNGBDBM50116766((6S)-N(6)-propyl-4,5,6,7-tetrahydro-1,3-benzothiaz...)
Affinity DataKi:  5.60nMAssay Description:Displacement of [3H]-7-OH-DPAT from human D3R expressed in HEK293 cell membranes measured after 90 mins in Tris buffer containing NaCl by topcount as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetD(3) dopamine receptor(Human)
National Institute of Neurological Disorders and Stroke

Curated by ChEMBL
LigandPNGBDBM50527993(CHEMBL4458958 | US11634404, Compound 74)
Affinity DataEC50:  6.40nMAssay Description:Agonist activity at human D3R expressed in CHOK1 cells assessed as induction of beta-arrestin recruitment measured after 90 mins by beta-galactosidas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
National Institute of Neurological Disorders and Stroke

Curated by ChEMBL
LigandPNGBDBM55121(cid_65340 | Dopamine | SMR000059081 | 4-(2-aminoet...)
Affinity DataEC50:  6.40nMAssay Description:Agonist activity at human D3R expressed in CHOK1 cells assessed as induction of beta-arrestin recruitment measured after 90 mins by beta-galactosidas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
National Institute of Neurological Disorders and Stroke

Curated by ChEMBL
LigandPNGBDBM50528018(CHEMBL4575155 | US11634404, Compound 76)
Affinity DataEC50:  6.90nMAssay Description:Agonist activity at human D3R expressed in CHOK1 cells assessed as induction of beta-arrestin recruitment measured after 90 mins by beta-galactosidas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
National Institute of Neurological Disorders and Stroke

Curated by ChEMBL
LigandPNGBDBM50528027(CHEMBL4538010 | US11634404, Compound 106)
Affinity DataEC50:  7nMAssay Description:Agonist activity at human D3R expressed in CHOK1 cells assessed as induction of beta-arrestin recruitment measured after 90 mins by beta-galactosidas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
National Institute of Neurological Disorders and Stroke

Curated by ChEMBL
LigandPNGBDBM50116766((6S)-N(6)-propyl-4,5,6,7-tetrahydro-1,3-benzothiaz...)
Affinity DataKi:  8.20nMAssay Description:Displacement of [3H]-methylspiperon from human D3R expressed in HEK293 cell membranes measured after 90 mins in EBSS buffer by topcount assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetD(3) dopamine receptor(Human)
National Institute of Neurological Disorders and Stroke

Curated by ChEMBL
LigandPNGBDBM50527976(CHEMBL4574338 | US11634404, Compound 2)
Affinity DataEC50:  9.20nMAssay Description:Agonist activity at human D3R expressed in CHOK1 cells assessed as induction of beta-arrestin recruitment measured after 90 mins by beta-galactosidas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
National Institute of Neurological Disorders and Stroke

Curated by ChEMBL
LigandPNGBDBM50400511(CHEMBL2203406)
Affinity DataEC50:  9.30nMAssay Description:Agonist activity at human D3R expressed in CHOK1 cells assessed as induction of beta-arrestin recruitment measured after 90 mins by beta-galactosidas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
National Institute of Neurological Disorders and Stroke

Curated by ChEMBL
LigandPNGBDBM50527989(CHEMBL4435730 | US11634404, Compound 82)
Affinity DataEC50:  9.5nMAssay Description:Agonist activity at human D3R expressed in CHOK1 cells assessed as induction of beta-arrestin recruitment measured after 90 mins by beta-galactosidas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
National Institute of Neurological Disorders and Stroke

Curated by ChEMBL
LigandPNGBDBM50528017(CHEMBL4551448 | US11634404, Compound 75)
Affinity DataEC50:  13nMAssay Description:Agonist activity at human D3R expressed in CHOK1 cells assessed as induction of beta-arrestin recruitment measured after 90 mins by beta-galactosidas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
National Institute of Neurological Disorders and Stroke

Curated by ChEMBL
LigandPNGBDBM50116766((6S)-N(6)-propyl-4,5,6,7-tetrahydro-1,3-benzothiaz...)
Affinity DataKi:  13nMAssay Description:Displacement of [3H]-methylspiperon from human D3R expressed in HEK293 cell membranes measured after 90 mins in Tris buffer by topcount assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetD(3) dopamine receptor(Human)
National Institute of Neurological Disorders and Stroke

Curated by ChEMBL
LigandPNGBDBM50528025(CHEMBL4470996 | US11634404, Compound 6)
Affinity DataEC50:  13nMAssay Description:Agonist activity at human D3R expressed in CHOK1 cells assessed as induction of beta-arrestin recruitment measured after 90 mins by beta-galactosidas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
National Institute of Neurological Disorders and Stroke

Curated by ChEMBL
LigandPNGBDBM50527972(CHEMBL4476784 | US11634404, Compound 1)
Affinity DataKi:  13nMAssay Description:Displacement of [3H]-7-OH-DPAT from human D3R expressed in HEK293 cell membranes measured after 90 mins in Tris buffer containing MgCl2 by topcount a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
National Institute of Neurological Disorders and Stroke

Curated by ChEMBL
LigandPNGBDBM50060417(CHEMBL297784 | SB 206553 | SB-206553 | 5-Methyl-3,...)
Affinity DataEC50:  13nMAssay Description:Antagonist activity at recombinant human 5-HT2B receptor expressed in CHOK1 cells assessed as inhibition of serotonin-induced increase in inositol1-p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
National Institute of Neurological Disorders and Stroke

Curated by ChEMBL
LigandPNGBDBM50528022(CHEMBL4447103 | US11634404, Compound 83)
Affinity DataEC50:  14nMAssay Description:Agonist activity at human D3R expressed in CHOK1 cells assessed as induction of beta-arrestin recruitment measured after 90 mins by beta-galactosidas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
National Institute of Neurological Disorders and Stroke

Curated by ChEMBL
LigandPNGBDBM50116766((6S)-N(6)-propyl-4,5,6,7-tetrahydro-1,3-benzothiaz...)
Affinity DataKi:  17nMAssay Description:Displacement of [3H]-methylspiperon from human D3R expressed in HEK293 cell membranes measured after 90 mins in Tris buffer containing NaCl by topcou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetD(3) dopamine receptor(Human)
National Institute of Neurological Disorders and Stroke

Curated by ChEMBL
LigandPNGBDBM50527972(CHEMBL4476784 | US11634404, Compound 1)
Affinity DataEC50:  17nMAssay Description:Agonist activity at RLuc8-fused human D3R Y198A mutant expressed in HEK293 cells co-expressing N-terminal Venus-tagged beta-arrestin2 and GRK3 assess...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
National Institute of Neurological Disorders and Stroke

Curated by ChEMBL
LigandPNGBDBM50527981(CHEMBL4563661 | US11634404, Compound 40)
Affinity DataEC50:  17nMAssay Description:Agonist activity at human D3R expressed in CHOK1 cells assessed as induction of beta-arrestin recruitment measured after 90 mins by beta-galactosidas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
National Institute of Neurological Disorders and Stroke

Curated by ChEMBL
LigandPNGBDBM50400511(CHEMBL2203406)
Affinity DataKi:  21nMAssay Description:Displacement of [3H]-methylspiperon from human D2RL expressed in HEK293 cell membranes measured after 90 mins by topcount assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
National Institute of Neurological Disorders and Stroke

Curated by ChEMBL
LigandPNGBDBM50527972(CHEMBL4476784 | US11634404, Compound 1)
Affinity DataEC50:  21nMAssay Description:Agonist activity at human D3R stably expressed in CHOK1 cells assessed as increase in ERK1/2 phosphorylation measured after 15 mins by AlphaScreen su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
National Institute of Neurological Disorders and Stroke

Curated by ChEMBL
LigandPNGBDBM50527972(CHEMBL4476784 | US11634404, Compound 1)
Affinity DataKi:  22nMAssay Description:Displacement of [3H]-7-OH-DPAT from human D3R expressed in HEK293 cell membranes measured after 90 mins in Tris buffer by topcount assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
National Institute of Neurological Disorders and Stroke

Curated by ChEMBL
LigandPNGBDBM50527980(CHEMBL4470786 | US11634404, Compound 73)
Affinity DataEC50:  26nMAssay Description:Agonist activity at human D3R expressed in CHOK1 cells assessed as induction of beta-arrestin recruitment measured after 90 mins by beta-galactosidas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
National Institute of Neurological Disorders and Stroke

Curated by ChEMBL
LigandPNGBDBM50116766((6S)-N(6)-propyl-4,5,6,7-tetrahydro-1,3-benzothiaz...)
Affinity DataKi:  29nMAssay Description:Displacement of [3H]-N-methylspiperone from recombinant human D4 receptor stably expressed in HEK cell membranes measured after 90 mins by microbeta ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
National Institute of Neurological Disorders and Stroke

Curated by ChEMBL
LigandPNGBDBM50400511(CHEMBL2203406)
Affinity DataKi:  30nMAssay Description:Displacement of [3H]-N-methylspiperone from D3 receptor (unknown origin) measured after 90 mins by microbeta scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
National Institute of Neurological Disorders and Stroke

Curated by ChEMBL
LigandPNGBDBM50400511(CHEMBL2203406)
Affinity DataKi:  32nMAssay Description:Displacement of [3H]-citalopram from human SERT receptor expressed in stable HEK cell membranes after 90 mins by microbeta scintillation counting met...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
National Institute of Neurological Disorders and Stroke

Curated by ChEMBL
LigandPNGBDBM50527988(CHEMBL4522471 | US11634404, Compound 121)
Affinity DataEC50:  32nMAssay Description:Agonist activity at human D3R expressed in CHOK1 cells assessed as induction of beta-arrestin recruitment measured after 90 mins by beta-galactosidas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
National Institute of Neurological Disorders and Stroke

Curated by ChEMBL
LigandPNGBDBM50527990(CHEMBL4566746 | US11634404, Compound 5)
Affinity DataEC50:  33nMAssay Description:Agonist activity at human D3R expressed in CHOK1 cells assessed as induction of beta-arrestin recruitment measured after 90 mins by beta-galactosidas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
National Institute of Neurological Disorders and Stroke

Curated by ChEMBL
LigandPNGBDBM55121(cid_65340 | Dopamine | SMR000059081 | 4-(2-aminoet...)
Affinity DataEC50:  33nMAssay Description:Agonist activity at RLuc8-fused human D3R Y365A mutant expressed in HEK293 cells co-expressing N-terminal Venus-tagged beta-arrestin2 and GRK3 assess...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
National Institute of Neurological Disorders and Stroke

Curated by ChEMBL
LigandPNGBDBM50528019(CHEMBL4518951 | US11634404, Compound 77)
Affinity DataEC50:  33nMAssay Description:Agonist activity at human D3R expressed in CHOK1 cells assessed as induction of beta-arrestin recruitment measured after 90 mins by beta-galactosidas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
National Institute of Neurological Disorders and Stroke

Curated by ChEMBL
LigandPNGBDBM50527974(CHEMBL4472566 | US11634404, Compound 94)
Affinity DataEC50:  34nMAssay Description:Agonist activity at human D3R expressed in CHOK1 cells assessed as induction of beta-arrestin recruitment measured after 90 mins by beta-galactosidas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
National Institute of Neurological Disorders and Stroke

Curated by ChEMBL
LigandPNGBDBM50527972(CHEMBL4476784 | US11634404, Compound 1)
Affinity DataEC50:  38nMAssay Description:Agonist activity at human D3R expressed in CHOK1 cells assessed as induction of beta-arrestin recruitment measured after 90 mins by beta-galactosidas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
National Institute of Neurological Disorders and Stroke

Curated by ChEMBL
LigandPNGBDBM50527994(CHEMBL4548340 | US11634404, Compound 81)
Affinity DataEC50:  38nMAssay Description:Agonist activity at human D3R expressed in CHOK1 cells assessed as induction of beta-arrestin recruitment measured after 90 mins by beta-galactosidas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
National Institute of Neurological Disorders and Stroke

Curated by ChEMBL
LigandPNGBDBM50527978(CHEMBL4445988 | US11634404, Compound 105)
Affinity DataEC50:  41nMAssay Description:Agonist activity at human D3R expressed in CHOK1 cells assessed as induction of beta-arrestin recruitment measured after 90 mins by beta-galactosidas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
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