Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 50013297
TargetHistone deacetylase 2(Human)
Beijing University of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50564474(CHEMBL4795802)
Affinity DataIC50: 23nMAssay Description:Inhibition of recombinant human HDAC2 using FLUOR-DE-LYS-Green as substrate incubated for 10 mins followed by substrate addition and measured after 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Beijing University of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50242817(CHEMBL4087968 | US20240150300, Compound Chidamide)
Affinity DataIC50: 67nMAssay Description:Inhibition of recombinant human HDAC2 using FLUOR-DE-LYS-Green as substrate incubated for 10 mins followed by substrate addition and measured after 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Beijing University of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50564474(CHEMBL4795802)
Affinity DataIC50: 71nMAssay Description:Inhibition of recombinant human HDAC1 using SIRT1 as substrate incubated for 10 mins followed by substrate addition and measured after 30 mins by flu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Beijing University of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM7533(2,6,9-Trisubstituted purine deriv. 28 | (2R)-2-[[6...)
Affinity DataIC50: 110nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged CDK2/CyclinA2 expressed in baculovirus infected Sf21 cells using histone H1 as substrate incuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Beijing University of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50242817(CHEMBL4087968 | US20240150300, Compound Chidamide)
Affinity DataIC50: 260nMAssay Description:Inhibition of recombinant human HDAC1 using SIRT1 as substrate incubated for 10 mins followed by substrate addition and measured after 30 mins by flu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Beijing University of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50564474(CHEMBL4795802)
Affinity DataIC50: 800nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged CDK2/CyclinA2 expressed in baculovirus infected Sf21 cells using histone H1 as substrate incuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed