Compile Data Set for Download or QSAR
Report error Found 21 Enz. Inhib. hit(s) with all data for entry = 50018483
TargetMonoacylglycerol lipase ABHD6(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50608631(CHEMBL5274434)
Affinity DataIC50: 2nMAssay Description:Inhibition of human recombinant ABHD6More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetMonoacylglycerol lipase ABHD6(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50211266(CHEMBL3906477)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of human recombinant ABHD6More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetMonoacylglycerol lipase ABHD6(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50608632(CHEMBL4279328)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of human recombinant ABHD6More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetMonoacylglycerol lipase ABHD6(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50211257(CHEMBL3895863 | US10583137, Compound 14)
Affinity DataIC50: 2.80nMAssay Description:Inhibition of human recombinant ABHD6More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetMonoacylglycerol lipase ABHD6(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM434879(US10583137, Compound 17 | tert-Butyl 3-benzyl-4-(4...)
Affinity DataIC50: 3.60nMAssay Description:Inhibition of human recombinant ABHD6More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetMonoacylglycerol lipase ABHD6(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50132713(Methyl arachidonoyl fluorophophonate | methyl -ico...)
Affinity DataIC50: 17nMAssay Description:Inhibition of ABHD6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetMonoacylglycerol lipase ABHD6(Mouse)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50608631(CHEMBL5274434)
Affinity DataIC50: 20nMAssay Description:Inhibition of ABHD6 in mouse brain membrane using HT-01 probe as substrate incubated for 30 mins by gel based competitive ABPP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetMonoacylglycerol lipase ABHD6(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50608630(CHEMBL5284566)
Affinity DataIC50: 44nMAssay Description:Inhibition of human ABHD6 expressed in HEK293 cells using 1-AG as substrate incubated for 90 mins by sensitive fluorescence glycerol assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetMonoacylglycerol lipase ABHD6(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM24567(Tetrahydrolipstatin | CHEMBL175247 | Xenical | (2S...)
Affinity DataIC50: 48nMAssay Description:Inhibition of human ABHD6 expressed in HEK293 cells using TAMRA-FP as substrate by SDS-PAGE gel based competitive ABPP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetMonoacylglycerol lipase ABHD6(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50608628(CHEMBL4068554)
Affinity DataIC50: 70nMAssay Description:Inhibition of human recombinant ABHD6 expressed in COS-7 cells in presence of FP-rhodamine labeled probe by SDS-PAGE based gel fluorescence scanning ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetMonoacylglycerol lipase ABHD6(Mouse)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM434879(US10583137, Compound 17 | tert-Butyl 3-benzyl-4-(4...)
Affinity DataIC50: 79nMAssay Description:Inhibition of ABHD6 in mouse brain membrane using HT-01 probe as substrate incubated for 30 mins by gel based competitive ABPP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetMonoacylglycerol lipase ABHD6(Mouse)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50211257(CHEMBL3895863 | US10583137, Compound 14)
Affinity DataIC50: 126nMAssay Description:Inhibition of ABHD6 in mouse brain membrane using HT-01 probe as substrate incubated for 30 mins by gel based competitive ABPP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetMonoacylglycerol lipase ABHD6(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50608627(CHEMBL5269646)
Affinity DataIC50: 350nMAssay Description:Inhibition of human recombinant ABHD6 expressed in COS-7 cells in presence of FP-rhodamine labeled probe by SDS-PAGE based gel fluorescence scanning ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetMonoacylglycerol lipase ABHD6(Mouse)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50608629(CHEMBL4303532)
Affinity DataIC50: 430nMAssay Description:Inhibition of ABHD6 in mouse brain membrane using FP-biotin as substrate incubated for 1 hr by LC-MS based ABPP-MudPIT analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetMonoacylglycerol lipase ABHD6(Mouse)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50220345((+/-)-oxiran-2-ylmethyl (9Z,12Z,15Z)-octadeca-9,12...)
Affinity DataIC50: 800nMAssay Description:Inhibition of mouse ABHD6 expressed in COS-7 cells using 2-[3H]AG as substrate incubated for 30 mins by liquid scintillation analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetFatty-acid amide hydrolase 1(Mouse)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50220345((+/-)-oxiran-2-ylmethyl (9Z,12Z,15Z)-octadeca-9,12...)
Affinity DataIC50: 900nMAssay Description:Inhibition of mouse FAAH expressed in COS-7 cells using [3H]AEA as substrate incubated for 30 mins by liquid scintillation analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetMonoacylglycerol lipase ABHD6(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50481947(CHEBI:8416 | GNF-Pf-476 | Pristimerine | PRISTIMER...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of ABHD6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetMonoacylglycerol lipase ABHD6(Mouse)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50220357((+/-)-oxiran-2-ylmethyl (9Z)-hexadec-9-enoate | CH...)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of mouse ABHD6 expressed in COS-7 cells using 2-[3H]AG as substrate incubated for 30 mins by liquid scintillation analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetFatty-acid amide hydrolase 1(Mouse)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50220357((+/-)-oxiran-2-ylmethyl (9Z)-hexadec-9-enoate | CH...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of mouse FAAH expressed in COS-7 cells using [3H]AEA as substrate incubated for 30 mins by liquid scintillation analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetMonoglyceride lipase(Mouse)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50220345((+/-)-oxiran-2-ylmethyl (9Z,12Z,15Z)-octadeca-9,12...)
Affinity DataIC50: 2.70E+5nMAssay Description:Inhibition of mouse MAGL expressed in COS-7 cells using 2-[3H]AG as substrate incubated for 30 mins by liquid scintillation analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetMonoacylglycerol lipase ABHD6(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50048620(CHEMBL3319620)
Affinity DataKi:  800nMAssay Description:Inhibition of human ABHD6 expressed in HEK293T cells assessed as inhibition constant using 2-AG as substrate incubated for 30 mins by fluorescence pl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed