Compile Data Set for Download or QSAR
Report error Found 31 Enz. Inhib. hit(s) with all data for entry = 50018484
TargetMonocarboxylate transporter 4(Human)
Shobhaben Pratapbhai Patel School of Pharmacy & Technology Management

Curated by ChEMBL
LigandPNGBDBM356917(US10214492, Example 268 | US11292767, Example 268)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of MCT4 in human MDA-MB-231 cells by BCECF-AM dye based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetMonocarboxylate transporter 4(Human)
Shobhaben Pratapbhai Patel School of Pharmacy & Technology Management

Curated by ChEMBL
LigandPNGBDBM356915(US10214492, Example 266 | US11292767, Example 266)
Affinity DataIC50: 0.360nMAssay Description:Inhibition of MCT4 in human MDA-MB-231 cells by BCECF-AM dye based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetMonocarboxylate transporter 4(Human)
Shobhaben Pratapbhai Patel School of Pharmacy & Technology Management

Curated by ChEMBL
LigandPNGBDBM356916(US10214492, Example 267 | US11292767, Example 267)
Affinity DataIC50: 0.570nMAssay Description:Inhibition of MCT4 in human MDA-MB-231 cells by BCECF-AM dye based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetMonocarboxylate transporter 1(Human)
Shobhaben Pratapbhai Patel School of Pharmacy & Technology Management

Curated by ChEMBL
LigandPNGBDBM50092069(CHEMBL3582422 | US9296728, 20)
Affinity DataIC50: 8nMAssay Description:Inhibition of MCT1 (unknown origin) assessed as reduction in [14C]lactate uptake incubated for 20 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetMonocarboxylate transporter 1(Human)
Shobhaben Pratapbhai Patel School of Pharmacy & Technology Management

Curated by ChEMBL
LigandPNGBDBM50092072(CHEMBL3582419 | US9296728, 14)
Affinity DataIC50: 9nMAssay Description:Inhibition of MCT1 (unknown origin) assessed as reduction in [14C]lactate uptake incubated for 20 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetMonocarboxylate transporter 1(Human)
Shobhaben Pratapbhai Patel School of Pharmacy & Technology Management

Curated by ChEMBL
LigandPNGBDBM50092071(CHEMBL3582420 | US9296728, 18)
Affinity DataIC50: 11nMAssay Description:Inhibition of MCT1 (unknown origin) assessed as reduction in [14C]lactate uptake incubated for 20 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetMonocarboxylate transporter 1(Rat)
Shobhaben Pratapbhai Patel School of Pharmacy & Technology Management

Curated by ChEMBL
LigandPNGBDBM50608638(CHEMBL4303684 | US20240091210, Compound UK5099)
Affinity DataIC50: 13nMAssay Description:Inhibition of MCT1 in rat Brain-like endothelial cells incubated for 15 mins in presence of [14C]lactic acid by scintillation counter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetMonocarboxylate transporter 4(Human)
Shobhaben Pratapbhai Patel School of Pharmacy & Technology Management

Curated by ChEMBL
LigandPNGBDBM50092072(CHEMBL3582419 | US9296728, 14)
Affinity DataIC50: 14nMAssay Description:Inhibition of MCT4 (unknown origin) assessed as reduction in [14C]lactate uptake incubated for 20 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetMonocarboxylate transporter 4(Human)
Shobhaben Pratapbhai Patel School of Pharmacy & Technology Management

Curated by ChEMBL
LigandPNGBDBM50092071(CHEMBL3582420 | US9296728, 18)
Affinity DataIC50: 17nMAssay Description:Inhibition of MCT4 (unknown origin) assessed as reduction in [14C]lactate uptake incubated for 20 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetMonocarboxylate transporter 4(Human)
Shobhaben Pratapbhai Patel School of Pharmacy & Technology Management

Curated by ChEMBL
LigandPNGBDBM50092069(CHEMBL3582422 | US9296728, 20)
Affinity DataIC50: 23nMAssay Description:Inhibition of MCT4 (unknown origin) assessed as reduction in [14C]lactate uptake incubated for 20 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetMonocarboxylate transporter 1(Human)
Shobhaben Pratapbhai Patel School of Pharmacy & Technology Management

Curated by ChEMBL
LigandPNGBDBM50608633(CHEMBL3582501)
Affinity DataIC50: 25nMAssay Description:Inhibition of MCT1 (unknown origin) assessed as reduction in [14C]lactate uptake incubated for 20 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetMonocarboxylate transporter 4(Human)
Shobhaben Pratapbhai Patel School of Pharmacy & Technology Management

Curated by ChEMBL
LigandPNGBDBM214697(US9296728, 19)
Affinity DataIC50: 32nMAssay Description:Inhibition of MCT4 (unknown origin) assessed as reduction in [14C]lactate uptake incubated for 20 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetMonocarboxylate transporter 1(Human)
Shobhaben Pratapbhai Patel School of Pharmacy & Technology Management

Curated by ChEMBL
LigandPNGBDBM50092070(CHEMBL3582421 | US9296728, 15)
Affinity DataIC50: 34nMAssay Description:Inhibition of MCT1 (unknown origin) assessed as reduction in [14C]lactate uptake incubated for 20 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetMonocarboxylate transporter 1(Human)
Shobhaben Pratapbhai Patel School of Pharmacy & Technology Management

Curated by ChEMBL
LigandPNGBDBM214697(US9296728, 19)
Affinity DataIC50: 37nMAssay Description:Inhibition of MCT1 (unknown origin) assessed as reduction in [14C]lactate uptake incubated for 20 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetMonocarboxylate transporter 1(Human)
Shobhaben Pratapbhai Patel School of Pharmacy & Technology Management

Curated by ChEMBL
LigandPNGBDBM214698(US9296728, 21)
Affinity DataIC50: 48nMAssay Description:Inhibition of MCT1 (unknown origin) assessed as reduction in [14C]lactate uptake incubated for 20 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetMonocarboxylate transporter 4(Human)
Shobhaben Pratapbhai Patel School of Pharmacy & Technology Management

Curated by ChEMBL
LigandPNGBDBM214698(US9296728, 21)
Affinity DataIC50: 53nMAssay Description:Inhibition of MCT4 (unknown origin) assessed as reduction in [14C]lactate uptake incubated for 20 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetMonocarboxylate transporter 4(Human)
Shobhaben Pratapbhai Patel School of Pharmacy & Technology Management

Curated by ChEMBL
LigandPNGBDBM50608633(CHEMBL3582501)
Affinity DataIC50: 58nMAssay Description:Inhibition of MCT4 (unknown origin) assessed as reduction in [14C]lactate uptake incubated for 20 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetMonocarboxylate transporter 1(Rat)
Shobhaben Pratapbhai Patel School of Pharmacy & Technology Management

Curated by ChEMBL
LigandPNGBDBM50608639(CHEMBL4793546)
Affinity DataIC50: 66nMAssay Description:Inhibition of MCT1 in rat Brain-like endothelial cells incubated for 15 mins in presence of [14C]lactic acid by scintillation counter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetMonocarboxylate transporter 4(Human)
Shobhaben Pratapbhai Patel School of Pharmacy & Technology Management

Curated by ChEMBL
LigandPNGBDBM50092070(CHEMBL3582421 | US9296728, 15)
Affinity DataIC50: 85nMAssay Description:Inhibition of MCT4 (unknown origin) assessed as reduction in [14C]lactate uptake incubated for 20 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetMonocarboxylate transporter 1(Rat)
Shobhaben Pratapbhai Patel School of Pharmacy & Technology Management

Curated by ChEMBL
LigandPNGBDBM50608637(CHEMBL5280660)
Affinity DataIC50: 97nMAssay Description:Inhibition of MCT1 in rat Brain-like endothelial cells incubated for 15 mins in presence of [14C]lactate by BCA protein assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetMonocarboxylate transporter 1(Rat)
Shobhaben Pratapbhai Patel School of Pharmacy & Technology Management

Curated by ChEMBL
LigandPNGBDBM50608636(CHEMBL5285345)
Affinity DataIC50: 408nMAssay Description:Inhibition of MCT1 in rat Brain-like endothelial cells incubated for 15 mins in presence of [14C]lactate by BCA protein assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetMonocarboxylate transporter 1(Rat)
Shobhaben Pratapbhai Patel School of Pharmacy & Technology Management

Curated by ChEMBL
LigandPNGBDBM50608640(CHEMBL5283025)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of MCT1 in rat Brain-like endothelial cells incubated for 15 mins in presence of [14C]lactic acid by scintillation counter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetMonocarboxylate transporter 1(Rat)
Shobhaben Pratapbhai Patel School of Pharmacy & Technology Management

Curated by ChEMBL
LigandPNGBDBM50608635(CHEMBL5268352)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of MCT1 in rat Brain-like endothelial cells incubated for 15 mins in presence of [14C]lactate by BCA protein assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetMonocarboxylate transporter 1(Rat)
Shobhaben Pratapbhai Patel School of Pharmacy & Technology Management

Curated by ChEMBL
LigandPNGBDBM50608634(CHEMBL5280998)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of MCT1 in rat Brain-like endothelial cells incubated for 15 mins in presence of [14C]lactate by BCA protein assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetMonocarboxylate transporter 1(Human)
Shobhaben Pratapbhai Patel School of Pharmacy & Technology Management

Curated by ChEMBL
LigandPNGBDBM4350((2E)-2-cyano-3-(4-hydroxyphenyl)prop-2-enoic acid ...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of MCT1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetMonocarboxylate transporter 4(Human)
Shobhaben Pratapbhai Patel School of Pharmacy & Technology Management

Curated by ChEMBL
LigandPNGBDBM4350((2E)-2-cyano-3-(4-hydroxyphenyl)prop-2-enoic acid ...)
Affinity DataIC50: 1.50E+5nMAssay Description:Inhibition of MCT4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetMonocarboxylate transporter 1(Human)
Shobhaben Pratapbhai Patel School of Pharmacy & Technology Management

Curated by ChEMBL
LigandPNGBDBM50103571(CHEMBL3335793)
Affinity DataKi:  2nMAssay Description:Binding affinity to MCT1 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetMonocarboxylate transporter 1(Rat)
Shobhaben Pratapbhai Patel School of Pharmacy & Technology Management

Curated by ChEMBL
LigandPNGBDBM50606662(CHEMBL5221129)
Affinity DataKi:  2nMAssay Description:Binding affinity to MCT1 in rat Erythrocyte assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetMonocarboxylate transporter 2(Rat)
Shobhaben Pratapbhai Patel School of Pharmacy & Technology Management

Curated by ChEMBL
LigandPNGBDBM50606662(CHEMBL5221129)
Affinity DataKi: <10nMAssay Description:Binding affinity to MCT2 in rat Erythrocyte assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetMonocarboxylate transporter 2(Human)
Shobhaben Pratapbhai Patel School of Pharmacy & Technology Management

Curated by ChEMBL
LigandPNGBDBM50103571(CHEMBL3335793)
Affinity DataKi:  20nMAssay Description:Binding affinity to MCT2 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetMonocarboxylate transporter 4(Human)
Shobhaben Pratapbhai Patel School of Pharmacy & Technology Management

Curated by ChEMBL
LigandPNGBDBM50608641(Bindarit | AF 2838 | AF-2838 | BINDARIT)
Affinity DataKi:  3.02E+4nMAssay Description:Binding affinity to human MCT4 expressed in Xenopus laevis oocytes assessed as inhibition constant in presence of [14C]lactate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed