Compile Data Set for Download or QSAR
Report error Found 9 Enz. Inhib. hit(s) with all data for entry = 50010414
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM81939(NSC_62969 | VERAPAMIL | CAS_52-53-9)
Affinity DataIC50: 400nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50538665(CHEMBL4642567)
Affinity DataIC50: 5.57E+3nMAssay Description:Inhibition of CYP1A2 in human liver microsomes using isoform-specific probe substrates incubated for 15 to 30 mins by by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50538665(CHEMBL4642567)
Affinity DataIC50: 1.64E+4nMAssay Description:Inhibition of CYP2C19 in human liver microsomes using isoform-specific probe substrates incubated for 15 to 30 mins by by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50538665(CHEMBL4642567)
Affinity DataIC50: 2.93E+4nMAssay Description:Inhibition of CYP2C9 in human liver microsomes using isoform-specific probe substrates incubated for 15 to 30 mins by by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50538665(CHEMBL4642567)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetCytochrome P450 2B6(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50538665(CHEMBL4642567)
Affinity DataIC50: 3.93E+4nMAssay Description:Inhibition of CYP2B6 in human liver microsomes using isoform-specific probe substrates incubated for 15 to 30 mins by by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetCytochrome P450 2C8(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50538665(CHEMBL4642567)
Affinity DataIC50: 5.41E+4nMAssay Description:Inhibition of CYP2C8 in human liver microsomes using isoform-specific probe substrates incubated for 15 to 30 mins by by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50538665(CHEMBL4642567)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of CYP2D6 in human liver microsomes using isoform-specific probe substrates incubated for 15 to 30 mins by by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50538665(CHEMBL4642567)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using isoform-specific probe substrates incubated for 15 to 30 mins by by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed