Compile Data Set for Download or QSAR
Report error Found 108 Enz. Inhib. hit(s) with all data for entry = 50010964
LigandPNGBDBM50257179(CHEMBL2325622)
Affinity DataIC50: 0.550nMAssay Description:Inhibition of mouse NaV1.7/beta1/beta2 expressed in HEK293A cells by Ionworks high-throughput electrophysiology methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetSodium channel subunit beta-2(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50257179(CHEMBL2325622)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of human NaV1.7/beta1/beta2 expressed in HEK293A cells by Ionworks high-throughput electrophysiology methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetSodium channel subunit beta-2(Mouse)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50240267(CHEMBL2325014)
Affinity DataIC50: 4.90nMAssay Description:Inhibition of mouse NaV1.7/beta1/beta2 expressed in HEK293A cells by Ionworks high-throughput electrophysiology methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetSodium channel subunit beta-2(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM258102(US9493448, 4 | US9845313, Example 4)
Affinity DataIC50: 12nMAssay Description:Inhibition of human NaV1.7/beta1/beta2 expressed in HEK293A cells by Ionworks high-throughput electrophysiology methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetSodium channel subunit beta-2(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50240267(CHEMBL2325014)
Affinity DataIC50: 13nMAssay Description:Inhibition of human NaV1.7/beta1/beta2 expressed in HEK293A cells by Ionworks high-throughput electrophysiology methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetSodium channel subunit beta-2(Mouse)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM258162(US9493448, 64 | US9597330, Example 21 | US9845313,...)
Affinity DataIC50: 15nMAssay Description:Inhibition of mouse NaV1.7/beta1/beta2 expressed in HEK293A cells by Ionworks high-throughput electrophysiology methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetSodium channel subunit beta-2(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM258106(US9493448, 8 | US9845313, Example 8)
Affinity DataIC50: 17nMAssay Description:Inhibition of human NaV1.7/beta1/beta2 expressed in HEK293A cells by Ionworks high-throughput electrophysiology methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetSodium channel subunit beta-2(Mouse)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM258102(US9493448, 4 | US9845313, Example 4)
Affinity DataIC50: 17nMAssay Description:Inhibition of mouse NaV1.7/beta1/beta2 expressed in HEK293A cells by Ionworks high-throughput electrophysiology methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM258146(US9493448, 48 | US9493448, 122 | US9493448, 154 | ...)
Affinity DataIC50: 23nMAssay Description:Inhibition of human Nav1.7 expressed in CHO cells with -120 mV holding potential by whole cell manual patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetSodium channel subunit beta-2(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM258141(US9493448, 43 | US9597330, Example 10 | US9845313,...)
Affinity DataIC50: 24nMAssay Description:Inhibition of human NaV1.7/beta1/beta2 expressed in HEK293A cells by Ionworks high-throughput electrophysiology methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetSodium channel subunit beta-2(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM258146(US9493448, 48 | US9493448, 122 | US9493448, 154 | ...)
Affinity DataIC50: 24.5nMAssay Description:Inhibition of human NaV1.7/beta1/beta2 expressed in HEK293A cells by Ionworks high-throughput electrophysiology methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetSodium channel subunit beta-2(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM258146(US9493448, 48 | US9493448, 122 | US9493448, 154 | ...)
Affinity DataIC50: 25nMAssay Description:Inhibition of human NaV1.7/beta1/beta2 expressed in HEK293A cells by Ionworks high-throughput electrophysiology methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetSodium channel subunit beta-2(Mouse)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM258146(US9493448, 48 | US9493448, 122 | US9493448, 154 | ...)
Affinity DataIC50: 26.5nMAssay Description:Inhibition of mouse NaV1.7/beta1/beta2 expressed in HEK293A cells by Ionworks high-throughput electrophysiology methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetSodium channel subunit beta-2(Mouse)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM258146(US9493448, 48 | US9493448, 122 | US9493448, 154 | ...)
Affinity DataIC50: 27nMAssay Description:Inhibition of mouse NaV1.7/beta1/beta2 expressed in HEK293A cells by Ionworks high-throughput electrophysiology methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetSodium channel subunit beta-2(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM258113(US9493448, 15 | US9845313, Example 15)
Affinity DataIC50: 28nMAssay Description:Inhibition of human NaV1.7/beta1/beta2 expressed in HEK293A cells by Ionworks high-throughput electrophysiology methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetSodium channel subunit beta-2(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM258161(US9493448, 63 | BDBM301817)
Affinity DataIC50: 28nMAssay Description:Inhibition of human NaV1.7/beta1/beta2 expressed in HEK293A cells by Ionworks high-throughput electrophysiology methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetSodium channel subunit beta-2(Mouse)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM258118(US9493448, 20 | US9597330, Example 2 | US9845313, ...)
Affinity DataIC50: 28nMAssay Description:Inhibition of mouse NaV1.7/beta1/beta2 expressed in HEK293A cells by Ionworks high-throughput electrophysiology methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetSodium channel subunit beta-2(Mouse)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM258141(US9493448, 43 | US9597330, Example 10 | US9845313,...)
Affinity DataIC50: 28nMAssay Description:Inhibition of mouse NaV1.7/beta1/beta2 expressed in HEK293A cells by Ionworks high-throughput electrophysiology methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetSodium channel subunit beta-2(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM258144(US9493448, 46 | US9597330, Example 11 | US9845313,...)
Affinity DataIC50: 30nMAssay Description:Inhibition of human NaV1.7/beta1/beta2 expressed in HEK293A cells by Ionworks high-throughput electrophysiology methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetSodium channel subunit beta-2(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM258162(US9493448, 64 | US9597330, Example 21 | US9845313,...)
Affinity DataIC50: 31nMAssay Description:Inhibition of human NaV1.7/beta1/beta2 expressed in HEK293A cells by Ionworks high-throughput electrophysiology methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetSodium channel subunit beta-2(Mouse)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM258161(US9493448, 63 | BDBM301817)
Affinity DataIC50: 41nMAssay Description:Inhibition of mouse NaV1.7/beta1/beta2 expressed in HEK293A cells by Ionworks high-throughput electrophysiology methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetSodium channel subunit beta-2(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM258118(US9493448, 20 | US9597330, Example 2 | US9845313, ...)
Affinity DataIC50: 45nMAssay Description:Inhibition of human NaV1.7/beta1/beta2 expressed in HEK293A cells by Ionworks high-throughput electrophysiology methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetSodium channel subunit beta-2(Mouse)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM258144(US9493448, 46 | US9597330, Example 11 | US9845313,...)
Affinity DataIC50: 56nMAssay Description:Inhibition of mouse NaV1.7/beta1/beta2 expressed in HEK293A cells by Ionworks high-throughput electrophysiology methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetSodium channel subunit beta-2(Mouse)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM258146(US9493448, 48 | US9493448, 122 | US9493448, 154 | ...)
Affinity DataIC50: 59nMAssay Description:Inhibition of mouse Nav1.7/beta1/beta2 expressed in HEK293A cells with -120 mV holding potential by whole cell manual patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetSodium channel subunit beta-2(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM258125(US9493448, 27 | US9597330, Example 4 | US9845313, ...)
Affinity DataIC50: 60nMAssay Description:Inhibition of human NaV1.7/beta1/beta2 expressed in HEK293A cells by Ionworks high-throughput electrophysiology methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetSodium channel subunit beta-2(Mouse)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM258125(US9493448, 27 | US9597330, Example 4 | US9845313, ...)
Affinity DataIC50: 96nMAssay Description:Inhibition of mouse NaV1.7/beta1/beta2 expressed in HEK293A cells by Ionworks high-throughput electrophysiology methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetSodium channel subunit beta-2(Mouse)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM258113(US9493448, 15 | US9845313, Example 15)
Affinity DataIC50: 100nMAssay Description:Inhibition of mouse NaV1.7/beta1/beta2 expressed in HEK293A cells by Ionworks high-throughput electrophysiology methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetSodium channel subunit beta-2(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM258123(US9493448, 25 | US9597330, Example 3 | US9845313, ...)
Affinity DataIC50: 113nMAssay Description:Inhibition of human NaV1.7/beta1/beta2 expressed in HEK293A cells by Ionworks high-throughput electrophysiology methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetSodium channel subunit beta-2(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM258112(US9493448, 14 | US9493448, 31 | US9597330, Example...)
Affinity DataIC50: 180nMAssay Description:Inhibition of human NaV1.7/beta1/beta2 expressed in HEK293A cells by Ionworks high-throughput electrophysiology methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetSodium channel subunit beta-2(Mouse)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM258106(US9493448, 8 | US9845313, Example 8)
Affinity DataIC50: 240nMAssay Description:Inhibition of mouse NaV1.7/beta1/beta2 expressed in HEK293A cells by Ionworks high-throughput electrophysiology methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetSodium channel subunit beta-2(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM258103(US9493448, 5 | US9493448, 10)
Affinity DataIC50: 290nMAssay Description:Inhibition of human NaV1.7/beta1/beta2 expressed in HEK293A cells by Ionworks high-throughput electrophysiology methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetSodium channel subunit beta-2(Mouse)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM258123(US9493448, 25 | US9597330, Example 3 | US9845313, ...)
Affinity DataIC50: 400nMAssay Description:Inhibition of mouse NaV1.7/beta1/beta2 expressed in HEK293A cells by Ionworks high-throughput electrophysiology methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetSodium channel protein type 8 subunit alpha(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM258146(US9493448, 48 | US9493448, 122 | US9493448, 154 | ...)
Affinity DataIC50: 475nMAssay Description:Inhibition of human Nav1.6 expressed in CHO cells with -120 mV holding potential by whole cell manual patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetSodium channel subunit beta-2(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM258128(US9493448, 30 | US9845313, Example 30)
Affinity DataIC50: 495nMAssay Description:Inhibition of human NaV1.7/beta1/beta2 expressed in HEK293A cells by Ionworks high-throughput electrophysiology methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetSodium channel subunit beta-2(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50543814(CHEMBL4644497)
Affinity DataIC50: 800nMAssay Description:Inhibition of human NaV1.7/beta1/beta2 expressed in HEK293A cells by Ionworks high-throughput electrophysiology methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetSodium channel subunit beta-2(Mouse)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM258112(US9493448, 14 | US9493448, 31 | US9597330, Example...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of mouse NaV1.7/beta1/beta2 expressed in HEK293A cells by Ionworks high-throughput electrophysiology methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetSodium channel protein type 2 subunit alpha(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM258146(US9493448, 48 | US9493448, 122 | US9493448, 154 | ...)
Affinity DataIC50: 1.96E+3nMAssay Description:Inhibition of human Nav1.2 expressed in CHO cells with -120 mV holding potential by whole cell manual patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetSodium channel subunit beta-2(Mouse)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM258103(US9493448, 5 | US9493448, 10)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of mouse NaV1.7/beta1/beta2 expressed in HEK293A cells by Ionworks high-throughput electrophysiology methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetSodium channel subunit beta-2(Mouse)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM258128(US9493448, 30 | US9845313, Example 30)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of mouse NaV1.7/beta1/beta2 expressed in HEK293A cells by Ionworks high-throughput electrophysiology methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM258146(US9493448, 48 | US9493448, 122 | US9493448, 154 | ...)
Affinity DataIC50: 4.90E+3nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM258146(US9493448, 48 | US9493448, 122 | US9493448, 154 | ...)
Affinity DataIC50: 8.70E+3nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
LigandPNGBDBM258113(US9493448, 15 | US9845313, Example 15)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of human NaV1.1/beta1/beta2 expressed in HEK293A cells by Ionworks high-throughput electrophysiology methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
LigandPNGBDBM258161(US9493448, 63 | BDBM301817)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of human NaV1.1/beta1/beta2 expressed in HEK293A cells by Ionworks high-throughput electrophysiology methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
LigandPNGBDBM258162(US9493448, 64 | US9597330, Example 21 | US9845313,...)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of human NaV1.1/beta1/beta2 expressed in HEK293A cells by Ionworks high-throughput electrophysiology methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
LigandPNGBDBM258106(US9493448, 8 | US9845313, Example 8)
Affinity DataIC50: 2.60E+4nMAssay Description:Inhibition of human NaV1.1/beta1/beta2 expressed in HEK293A cells by Ionworks high-throughput electrophysiology methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
LigandPNGBDBM258106(US9493448, 8 | US9845313, Example 8)
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of human NaV1.5/beta1/beta2 expressed in HEK293A cells by Ionworks high-throughput electrophysiology methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetSodium channel subunit beta-2(Mouse)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50543814(CHEMBL4644497)
Affinity DataIC50: 3.53E+4nMAssay Description:Inhibition of mouse NaV1.7/beta1/beta2 expressed in HEK293A cells by Ionworks high-throughput electrophysiology methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
LigandPNGBDBM258102(US9493448, 4 | US9845313, Example 4)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of human NaV1.5/beta1/beta2 expressed in HEK293A cells by Ionworks high-throughput electrophysiology methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetSodium channel subunit beta-2(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM258235(US9493448, 142 | US9845313, Example 142)
Affinity DataIC50: 4.70E+4nMAssay Description:Inhibition of human NaV1.7/beta1/beta2 expressed in HEK293A cells by Ionworks high-throughput electrophysiology methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
LigandPNGBDBM258125(US9493448, 27 | US9597330, Example 4 | US9845313, ...)
Affinity DataIC50: 5.20E+4nMAssay Description:Inhibition of human NaV1.1/beta1/beta2 expressed in HEK293A cells by Ionworks high-throughput electrophysiology methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
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