Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with all data for entry = 50010421
TargetPeptidyl-prolyl cis-trans isomerase FKBP5(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50538683(CHEMBL662 | CHEBI:16540 | SR-1C9)
Affinity DataKd:  1.30E+6nMAssay Description:Binding affinity to 15N-labeled FKBP51 (1 to 140 residues) (unknown origin) expressed in Escherichia coli OD2N by two-dimensional 1H/15N HSQC NMR spe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP5(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM10(CHEMBL12193 | piperidin-2-one | delta-valerolactam)
Affinity DataKd:  2.80E+6nMAssay Description:Binding affinity to 15N-labeled FKBP51 (1 to 140 residues) (unknown origin) expressed in Escherichia coli OD2N by two-dimensional 1H/15N HSQC NMR spe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPeptidyl-prolyl cis-trans isomerase FKBP5(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM7882(CHEMBL540 | 1H-imidazole | imidazole | Imidazole (...)
Affinity DataKd:  4.40E+6nMAssay Description:Binding affinity to 15N-labeled FKBP51 (1 to 140 residues) (unknown origin) expressed in Escherichia coli OD2N by two-dimensional 1H/15N HSQC NMR spe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP5(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50538684(CHEMBL1230309 | CHEBI:40035)
Affinity DataKd:  2.90E+6nMAssay Description:Binding affinity to 15N-labeled FKBP51 (1 to 140 residues) (unknown origin) expressed in Escherichia coli OD2N by two-dimensional 1H/15N HSQC NMR spe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed