Compile Data Set for Download or QSAR
Report error Found 24 Enz. Inhib. hit(s) with all data for entry = 50010617
TargetKappa-type opioid receptor(Human)
D'Annunzio University of Chieti���Pescara

Curated by ChEMBL
LigandPNGBDBM50540614(CHEMBL4636807)
Affinity DataEC50:  4.10E+3nMAssay Description:Agonist activity at human KOR expressed in CHO cell membranes after 1 hr by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
D'Annunzio University of Chieti���Pescara

Curated by ChEMBL
LigandPNGBDBM50540613(CHEMBL4641588)
Affinity DataEC50:  250nMAssay Description:Agonist activity at human DOR expressed in CHO cell membranes after 1 hr by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
D'Annunzio University of Chieti���Pescara

Curated by ChEMBL
LigandPNGBDBM50540614(CHEMBL4636807)
Affinity DataEC50:  190nMAssay Description:Agonist activity at human DOR expressed in CHO cell membranes after 1 hr by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
D'Annunzio University of Chieti���Pescara

Curated by ChEMBL
LigandPNGBDBM50540615(CHEMBL4638703)
Affinity DataEC50:  460nMAssay Description:Agonist activity at human KOR expressed in CHO cell membranes after 1 hr by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
D'Annunzio University of Chieti���Pescara

Curated by ChEMBL
LigandPNGBDBM50540615(CHEMBL4638703)
Affinity DataEC50:  40nMAssay Description:Agonist activity at human DOR expressed in CHO cell membranes after 1 hr by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
D'Annunzio University of Chieti���Pescara

Curated by ChEMBL
LigandPNGBDBM50039029(CHEMBL13470 | 3-[(4-Allyl-2,5-dimethyl-piperazin-1...)
Affinity DataEC50:  7.60nMAssay Description:Agonist activity at human DOR expressed in CHO cell membranes after 1 hr by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
D'Annunzio University of Chieti���Pescara

Curated by ChEMBL
LigandPNGBDBM50540615(CHEMBL4638703)
Affinity DataEC50:  21nMAssay Description:Agonist activity at human MOR expressed in CHO cell membranes after 1 hr by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
D'Annunzio University of Chieti���Pescara

Curated by ChEMBL
LigandPNGBDBM50540613(CHEMBL4641588)
Affinity DataEC50:  1.00E+3nMAssay Description:Agonist activity at human KOR expressed in CHO cell membranes after 1 hr by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
D'Annunzio University of Chieti���Pescara

Curated by ChEMBL
LigandPNGBDBM21015([tyrosyl-3,5-3H(N)]-D-Ala2-Mephe4-glyol5-enkephali...)
Affinity DataEC50:  23nMAssay Description:Agonist activity at human MOR expressed in CHO cell membranes after 1 hr by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
D'Annunzio University of Chieti���Pescara

Curated by ChEMBL
LigandPNGBDBM50000296(CHEMBL441765 | CHEMBL482811 | U-50488H | US1149237...)
Affinity DataEC50:  80nMAssay Description:Agonist activity at human KOR expressed in CHO cell membranes after 1 hr by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
D'Annunzio University of Chieti���Pescara

Curated by ChEMBL
LigandPNGBDBM50540613(CHEMBL4641588)
Affinity DataEC50:  270nMAssay Description:Agonist activity at human MOR expressed in CHO cell membranes after 1 hr by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
D'Annunzio University of Chieti���Pescara

Curated by ChEMBL
LigandPNGBDBM50540614(CHEMBL4636807)
Affinity DataEC50:  290nMAssay Description:Agonist activity at human MOR expressed in CHO cell membranes after 1 hr by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
D'Annunzio University of Chieti���Pescara

Curated by ChEMBL
LigandPNGBDBM50540615(CHEMBL4638703)
Affinity DataKi:  15nMAssay Description:Displacement of [3H]diprenorphine human delta opioid receptor expressed in CHO cell membranes after 1 hr by micro beta2 scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
D'Annunzio University of Chieti���Pescara

Curated by ChEMBL
LigandPNGBDBM50000788([17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydro...)
Affinity DataKi:  43nMAssay Description:Displacement of [3H]diprenorphine human MOR expressed in CHO cell membranes after 1 hr by micro beta2 scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMu-type opioid receptor(Human)
D'Annunzio University of Chieti���Pescara

Curated by ChEMBL
LigandPNGBDBM50540615(CHEMBL4638703)
Affinity DataKi:  91nMAssay Description:Displacement of [3H]diprenorphine human MOR expressed in CHO cell membranes after 1 hr by micro beta2 scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
D'Annunzio University of Chieti���Pescara

Curated by ChEMBL
LigandPNGBDBM50540613(CHEMBL4641588)
Affinity DataKi:  98nMAssay Description:Displacement of [3H]diprenorphine human delta opioid receptor expressed in CHO cell membranes after 1 hr by micro beta2 scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
D'Annunzio University of Chieti���Pescara

Curated by ChEMBL
LigandPNGBDBM50000788([17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydro...)
Affinity DataKi:  120nMAssay Description:Displacement of [3H]diprenorphine human delta opioid receptor expressed in CHO cell membranes after 1 hr by micro beta2 scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
D'Annunzio University of Chieti���Pescara

Curated by ChEMBL
LigandPNGBDBM50540614(CHEMBL4636807)
Affinity DataKi:  120nMAssay Description:Displacement of [3H]diprenorphine human delta opioid receptor expressed in CHO cell membranes after 1 hr by micro beta2 scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
D'Annunzio University of Chieti���Pescara

Curated by ChEMBL
LigandPNGBDBM50000296(CHEMBL441765 | CHEMBL482811 | U-50488H | US1149237...)
Affinity DataKi:  120nMAssay Description:Displacement of [3H]diprenorphine human kappa opioid receptor expressed in CHO cell membranes after 1 hr by micro beta2 scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
D'Annunzio University of Chieti���Pescara

Curated by ChEMBL
LigandPNGBDBM50540613(CHEMBL4641588)
Affinity DataKi:  510nMAssay Description:Displacement of [3H]diprenorphine human MOR expressed in CHO cell membranes after 1 hr by micro beta2 scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
D'Annunzio University of Chieti���Pescara

Curated by ChEMBL
LigandPNGBDBM50540614(CHEMBL4636807)
Affinity DataKi:  790nMAssay Description:Displacement of [3H]diprenorphine human MOR expressed in CHO cell membranes after 1 hr by micro beta2 scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
D'Annunzio University of Chieti���Pescara

Curated by ChEMBL
LigandPNGBDBM50540613(CHEMBL4641588)
Affinity DataKi: >3.33E+3nMAssay Description:Displacement of [3H]diprenorphine human kappa opioid receptor expressed in CHO cell membranes after 1 hr by micro beta2 scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
D'Annunzio University of Chieti���Pescara

Curated by ChEMBL
LigandPNGBDBM50540615(CHEMBL4638703)
Affinity DataKi: >3.33E+3nMAssay Description:Displacement of [3H]diprenorphine human kappa opioid receptor expressed in CHO cell membranes after 1 hr by micro beta2 scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
D'Annunzio University of Chieti���Pescara

Curated by ChEMBL
LigandPNGBDBM50540614(CHEMBL4636807)
Affinity DataKi: >3.33E+3nMAssay Description:Displacement of [3H]diprenorphine human kappa opioid receptor expressed in CHO cell membranes after 1 hr by micro beta2 scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed