Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with all data for entry = 50010532
TargetProstaglandin E synthase(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50539779(CHEMBL4647475)
Affinity DataIC50: 700nMAssay Description:Inhibition of mPGES1 in human A549 cells assessed as reduction in IL-1beta induced PGE2 release using PGH2 as substrate preincubated for 15 mins foll...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50539778(CHEMBL4636106)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of mPGES1 in human A549 cells assessed as reduction in IL-1beta induced PGE2 release using PGH2 as substrate preincubated for 15 mins foll...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50539781(CHEMBL4647634)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of mPGES1 in human A549 cells assessed as reduction in IL-1beta induced PGE2 release using PGH2 as substrate preincubated for 15 mins foll...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50539780(CHEMBL4643829)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of mPGES1 in human A549 cells assessed as reduction in IL-1beta induced PGE2 release using PGH2 as substrate preincubated for 15 mins foll...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed