Compile Data Set for Download or QSAR
Report error Found 24 Enz. Inhib. hit(s) with all data for entry = 50010739
TargetCoagulation factor XI(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50541586(CHEMBL4638245)
Affinity DataKi:  0.260nMAssay Description:Inhibition of human factor11a using pyro-Glu-Pro-Arg-pNA(para-nitroaniline) substrate by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetCoagulation factor XI(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50541581(CHEMBL4646341)
Affinity DataKi:  0.5nMAssay Description:Inhibition of human factor11a using pyro-Glu-Pro-Arg-pNA(para-nitroaniline) substrate by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetCoagulation factor XI(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50541577(CHEMBL4646441)
Affinity DataKi:  0.600nMAssay Description:Inhibition of human factor11a using pyro-Glu-Pro-Arg-pNA(para-nitroaniline) substrate by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetCoagulation factor XI(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50541576(CHEMBL4644510)
Affinity DataKi:  0.700nMAssay Description:Inhibition of human factor11a using pyro-Glu-Pro-Arg-pNA(para-nitroaniline) substrate by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetCoagulation factor XI(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50541582(CHEMBL4636247)
Affinity DataKi:  0.900nMAssay Description:Inhibition of human factor11a using pyro-Glu-Pro-Arg-pNA(para-nitroaniline) substrate by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetCoagulation factor XI(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50541579(CHEMBL4637480)
Affinity DataKi:  1.60nMAssay Description:Inhibition of human factor11a using pyro-Glu-Pro-Arg-pNA(para-nitroaniline) substrate by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetCoagulation factor XI(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50541578(CHEMBL4638837)
Affinity DataKi:  1.80nMAssay Description:Inhibition of human factor11a using pyro-Glu-Pro-Arg-pNA(para-nitroaniline) substrate by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetVitamin K-dependent protein C(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50541586(CHEMBL4638245)
Affinity DataKi:  1.90nMAssay Description:Inhibition of human activated protein C using pyro-Glu-Pro-Arg-pNA(para-nitroaniline) substrate by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetCoagulation factor XI(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50541580(CHEMBL4639313)
Affinity DataKi:  2.70nMAssay Description:Inhibition of human factor11a using pyro-Glu-Pro-Arg-pNA(para-nitroaniline) substrate by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetCoagulation factor XI(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50541583(CHEMBL4633639)
Affinity DataKi:  4.5nMAssay Description:Inhibition of human factor11a using pyro-Glu-Pro-Arg-pNA(para-nitroaniline) substrate by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetCoagulation factor XI(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50541585(CHEMBL4635155)
Affinity DataKi:  4.90nMAssay Description:Inhibition of human factor11a using pyro-Glu-Pro-Arg-pNA(para-nitroaniline) substrate by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetCoagulation factor XI(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50541584(CHEMBL4639498)
Affinity DataKi:  14nMAssay Description:Inhibition of human factor11a using pyro-Glu-Pro-Arg-pNA(para-nitroaniline) substrate by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetChymotrypsinogen B2(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50541586(CHEMBL4638245)
Affinity DataKi:  20nMAssay Description:Inhibition of human chymotrypsin by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetCoagulation factor XII(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50541586(CHEMBL4638245)
Affinity DataKi:  1.30E+3nMAssay Description:Inhibition of human factor-12a using H-(D)-CHT-Gly-ArgpNA substrate by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetCoagulation factor VII(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50541586(CHEMBL4638245)
Affinity DataKi:  2.40E+3nMAssay Description:Inhibition of human factor-7a using H-(D)-Ile-Pro-Arg-pNA substrate by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetTissue-type plasminogen activator(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50541586(CHEMBL4638245)
Affinity DataKi:  4.10E+3nMAssay Description:Inhibition of human tissue-type plasminogen activator using methyl-sulfonyl-D-cyclohexylalanyl-Gly-Arg-pNA substrate by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetPlasma kallikrein(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50541586(CHEMBL4638245)
Affinity DataKi: >6.00E+3nMAssay Description:Inhibition of human plasma kallikrein using H-(D)-Pro-Phe-Arg-pNA substrate by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50541586(CHEMBL4638245)
Affinity DataKi: >9.00E+3nMAssay Description:Inhibition of human factor-10a using N-benzoyl-Ile-Glu-(OH,OMe)-Gly-Arg-pNA substrate by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetProthrombin(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50541586(CHEMBL4638245)
Affinity DataKi: >1.30E+4nMAssay Description:Inhibition of human thrombin using pyro-Glu-Pro-Arg-pNA(para-nitroaniline substrate by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetTissue-type plasminogen activator(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50541586(CHEMBL4638245)
Affinity DataKi: >1.50E+4nMAssay Description:Inhibition of human tissue-type plasminogen activator using H-(D)-Val-Leu-Lys-pNA substrate by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50541586(CHEMBL4638245)
Affinity DataKi: >1.50E+4nMAssay Description:Inhibition of human urokinase using pyro-Glu-Gly-Arg-pNA substrate by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetPlasminogen(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50541586(CHEMBL4638245)
Affinity DataKi: >2.10E+4nMAssay Description:Inhibition of human plasmin using H-(D)-Val-Leu-Lys-pNA substrate by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetCoagulation factor VII(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50541586(CHEMBL4638245)
Affinity DataKi: >2.70E+4nMAssay Description:Inhibition of human factor-9a using Methyl-sulfonyl-D-cyclohexylglycyl-Gly-Arg-AMC substrate by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetKallikrein-1(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50541586(CHEMBL4638245)
Affinity DataKi: >3.00E+4nMAssay Description:Inhibition of human tissue kallikrein-1 by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed