Compile Data Set for Download or QSAR
Report error Found 19 Enz. Inhib. hit(s) with all data for entry = 50010776
TargetBifunctional epoxide hydrolase 2(Human)
Goethe-University

Curated by ChEMBL
LigandPNGBDBM50327809(1-(1-Propionylpiperidin-4-yl)-3-(4-(trifluorometho...)
Affinity DataIC50: 13nMAssay Description:Inhibition of recombinant human full length sEH (1 to 555 residues) expressed in Escherichia coli BL21 DE3 cells assessed as reduction in 6-methoxyna...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetLeukotriene A-4 hydrolase(Human)
Goethe-University

Curated by ChEMBL
LigandPNGBDBM23971(CHEMBL29292 | (2S)-2-[(2S,3R)-3-amino-2-hydroxy-4-...)
Affinity DataIC50: 266nMAssay Description:Inhibition of recombinant human full length C-terminal His6-tagged LTA4H expressed in Escherichia coli BL21 DE3 cells assessed as reduction in amino-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Goethe-University

Curated by ChEMBL
LigandPNGBDBM50541959(CHEMBL4649188)
Affinity DataIC50: 300nMAssay Description:Inhibition of recombinant human full length sEH (1 to 555 residues) expressed in Escherichia coli BL21 DE3 cells assessed as reduction in 6-methoxyna...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Goethe-University

Curated by ChEMBL
LigandPNGBDBM50541953(CHEMBL4644372)
Affinity DataIC50: 500nMAssay Description:Inhibition of recombinant human full length sEH (1 to 555 residues) expressed in Escherichia coli BL21 DE3 cells assessed as reduction in 6-methoxyna...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetLeukotriene A-4 hydrolase(Human)
Goethe-University

Curated by ChEMBL
LigandPNGBDBM50541959(CHEMBL4649188)
Affinity DataIC50: 570nMAssay Description:Inhibition of recombinant human full length C-terminal His6-tagged LTA4H expressed in Escherichia coli BL21 DE3 cells assessed as reduction in amino-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetLeukotriene A-4 hydrolase(Human)
Goethe-University

Curated by ChEMBL
LigandPNGBDBM50541960(CHEMBL4645053)
Affinity DataIC50: 670nMAssay Description:Inhibition of recombinant human full length C-terminal His6-tagged LTA4H expressed in Escherichia coli BL21 DE3 cells assessed as reduction in amino-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetLeukotriene A-4 hydrolase(Human)
Goethe-University

Curated by ChEMBL
LigandPNGBDBM50541952(CHEMBL4646891)
Affinity DataIC50: 690nMAssay Description:Inhibition of recombinant human full length C-terminal His6-tagged LTA4H expressed in Escherichia coli BL21 DE3 cells assessed as reduction in amino-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetLeukotriene A-4 hydrolase(Human)
Goethe-University

Curated by ChEMBL
LigandPNGBDBM50541953(CHEMBL4644372)
Affinity DataIC50: 750nMAssay Description:Inhibition of recombinant human full length C-terminal His6-tagged LTA4H expressed in Escherichia coli BL21 DE3 cells assessed as reduction in amino-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Goethe-University

Curated by ChEMBL
LigandPNGBDBM50541956(CHEMBL4635127)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of recombinant human full length sEH (1 to 555 residues) expressed in Escherichia coli BL21 DE3 cells assessed as reduction in 6-methoxyna...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetLeukotriene A-4 hydrolase(Human)
Goethe-University

Curated by ChEMBL
LigandPNGBDBM50541954(CHEMBL4640292)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of recombinant human full length C-terminal His6-tagged LTA4H expressed in Escherichia coli BL21 DE3 cells assessed as reduction in amino-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetLeukotriene A-4 hydrolase(Human)
Goethe-University

Curated by ChEMBL
LigandPNGBDBM50541958(CHEMBL4649795)
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of recombinant human full length C-terminal His6-tagged LTA4H expressed in Escherichia coli BL21 DE3 cells assessed as reduction in amino-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Goethe-University

Curated by ChEMBL
LigandPNGBDBM50541958(CHEMBL4649795)
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of recombinant human full length sEH (1 to 555 residues) expressed in Escherichia coli BL21 DE3 cells assessed as reduction in 6-methoxyna...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetLeukotriene A-4 hydrolase(Human)
Goethe-University

Curated by ChEMBL
LigandPNGBDBM50068107(CHEMBL3402237)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of recombinant human C-terminal His6-tagged LTA4H expressed in Escherichia coli BL21 DE3 cells using 7-amido-4-methylcoumarin as substrate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Goethe-University

Curated by ChEMBL
LigandPNGBDBM50541955(CHEMBL4644992)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human full length sEH (1 to 555 residues) expressed in Escherichia coli BL21 DE3 cells assessed as reduction in 6-methoxyna...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Goethe-University

Curated by ChEMBL
LigandPNGBDBM50541952(CHEMBL4646891)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of recombinant human full length sEH (1 to 555 residues) expressed in Escherichia coli BL21 DE3 cells assessed as reduction in 6-methoxyna...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Goethe-University

Curated by ChEMBL
LigandPNGBDBM50541957(CHEMBL4637146)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of recombinant human full length sEH (1 to 555 residues) expressed in Escherichia coli BL21 DE3 cells assessed as reduction in 6-methoxyna...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetLeukotriene A-4 hydrolase(Human)
Goethe-University

Curated by ChEMBL
LigandPNGBDBM50541961(CHEMBL4632833)
Affinity DataIC50: 1.83E+4nMAssay Description:Inhibition of recombinant human full length C-terminal His6-tagged LTA4H expressed in Escherichia coli BL21 DE3 cells assessed as reduction in amino-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Goethe-University

Curated by ChEMBL
LigandPNGBDBM50541954(CHEMBL4640292)
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of recombinant human full length sEH (1 to 555 residues) expressed in Escherichia coli BL21 DE3 cells assessed as reduction in 6-methoxyna...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Goethe-University

Curated by ChEMBL
LigandPNGBDBM50068107(CHEMBL3402237)
Affinity DataIC50: 7.90E+4nMAssay Description:Inhibition of recombinant human sEH using PHOME as substrate preincubated with enzyme for 10 mins prior to substrate addition by fluorescence based a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)