Compile Data Set for Download or QSAR
Report error Found 14 Enz. Inhib. hit(s) with all data for entry = 50012805
TargetNACHT, LRR and PYD domains-containing protein 3(Mouse)
Guangzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50560453(CHEMBL4740148)
Affinity DataIC50: 300nMAssay Description:Inhibition of NLRP3 inflammasome in mouse J774.A1 cells assessed as reduction in LPS-induced IL-1beta releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Mouse)
Guangzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50560452(CHEMBL4756259)
Affinity DataIC50: 400nMAssay Description:Inhibition of NLRP3 inflammasome in mouse J774.A1 cells assessed as reduction in LPS-induced IL-1beta releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Mouse)
Guangzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50560450(CHEMBL4798966)
Affinity DataIC50: 490nMAssay Description:Inhibition of NLRP3 inflammasome in mouse J774.A1 cells assessed as reduction in LPS-induced IL-1beta releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Mouse)
Guangzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50560451(CHEMBL4781662)
Affinity DataIC50: 500nMAssay Description:Inhibition of NLRP3 inflammasome in mouse J774.A1 cells assessed as reduction in LPS-induced IL-1beta releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Mouse)
Guangzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50324369(3,4-Bis-benzenesulfonyl-furazan 2-oxide | 3,4-bis(...)
Affinity DataIC50: 930nMAssay Description:Inhibition of NLRP3 inflammasome in mouse J774.A1 cells assessed as reduction in LPS-induced IL-1beta releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Guangzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50560453(CHEMBL4740148)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of NLRP3 inflammasome in human primary glial cells assessed as reduction in LPS-induced IL-1beta releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Mouse)
Guangzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50560454(CHEMBL4781244)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of NLRP3 inflammasome in mouse J774.A1 cells assessed as reduction in LPS-induced IL-1beta releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Guangzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50560451(CHEMBL4781662)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of NLRP3 inflammasome in human primary glial cells assessed as reduction in LPS-induced IL-1beta releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Guangzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50560454(CHEMBL4781244)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of NLRP3 inflammasome in human primary glial cells assessed as reduction in LPS-induced IL-1beta releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Guangzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50324369(3,4-Bis-benzenesulfonyl-furazan 2-oxide | 3,4-bis(...)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of NLRP3 inflammasome in human primary glial cells assessed as reduction in LPS-induced IL-1beta releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Guangzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50560452(CHEMBL4756259)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of NLRP3 inflammasome in human primary glial cells assessed as reduction in LPS-induced IL-1beta releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Mouse)
Guangzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50455476(CHEBI:6922 | Micheliolide)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of NLRP3 inflammasome in mouse J774.A1 cells assessed as reduction in LPS-induced IL-1beta releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Guangzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50560450(CHEMBL4798966)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of NLRP3 inflammasome in human primary glial cells assessed as reduction in LPS-induced IL-1beta releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Guangzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50455476(CHEBI:6922 | Micheliolide)
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of NLRP3 inflammasome in human primary glial cells assessed as reduction in LPS-induced IL-1beta releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed