Compile Data Set for Download or QSAR
Report error Found 10 Enz. Inhib. hit(s) with all data for entry = 50012886
TargetRho-associated protein kinase 2(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM25470(cid_5056270 | N-[4-(pyridin-4-yl)-1,3-thiazol-2-yl...)
Affinity DataIC50: 10nMAssay Description:Inhibition of ROCK2 (unknown origin) using C-terminus recombinant MBS (654-880 residues) as substrate incubated for 30 mins in presence of ATP by ELI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50561288(CHEMBL4781535)
Affinity DataIC50: 20nMAssay Description:Inhibition of ROCK2 (unknown origin) using C-terminus recombinant MBS (654-880 residues) as substrate incubated for 30 mins in presence of ATP by ELI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50561285(CHEMBL4778240)
Affinity DataIC50: 90nMAssay Description:Inhibition of ROCK2 (unknown origin) using C-terminus recombinant MBS (654-880 residues) as substrate incubated for 30 mins in presence of ATP by ELI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50561292(CHEMBL4784254)
Affinity DataIC50: 130nMAssay Description:Inhibition of ROCK2 (unknown origin) using C-terminus recombinant MBS (654-880 residues) as substrate incubated for 30 mins in presence of ATP by ELI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50561290(CHEMBL4762307)
Affinity DataIC50: 1.56E+3nMAssay Description:Inhibition of ROCK2 (unknown origin) using C-terminus recombinant MBS (654-880 residues) as substrate incubated for 30 mins in presence of ATP by ELI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50561289(CHEMBL4742283)
Affinity DataIC50: 1.73E+3nMAssay Description:Inhibition of ROCK2 (unknown origin) using C-terminus recombinant MBS (654-880 residues) as substrate incubated for 30 mins in presence of ATP by ELI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50561291(CHEMBL4761769)
Affinity DataIC50: 4.96E+3nMAssay Description:Inhibition of ROCK2 (unknown origin) using C-terminus recombinant MBS (654-880 residues) as substrate incubated for 30 mins in presence of ATP by ELI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50561287(CHEMBL4797086)
Affinity DataIC50: 8.56E+3nMAssay Description:Inhibition of ROCK2 (unknown origin) using C-terminus recombinant MBS (654-880 residues) as substrate incubated for 30 mins in presence of ATP by ELI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50561284(CHEMBL4784761)
Affinity DataIC50: 8.83E+3nMAssay Description:Inhibition of ROCK2 (unknown origin) using C-terminus recombinant MBS (654-880 residues) as substrate incubated for 30 mins in presence of ATP by ELI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50561286(CHEMBL4749216)
Affinity DataIC50: 9.12E+3nMAssay Description:Inhibition of ROCK2 (unknown origin) using C-terminus recombinant MBS (654-880 residues) as substrate incubated for 30 mins in presence of ATP by ELI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed