Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 50018761
TargetKallikrein-7(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50612151(CHEMBL5287216)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of KLK7 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetNeutrophil elastase(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50612149(CHEMBL5284383)
Affinity DataIC50: 0.730nMAssay Description:Inhibition of elastase in human neutrophil using MeOSuc-AAPV-AMC as substrate by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetNeutrophil elastase(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50429202(LYNGBYASTATIN 7)
Affinity DataIC50: 0.850nMAssay Description:Inhibition of elastase in human neutrophil using MeOSuc-AAPV-AMC as substrate by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetKallikrein-7(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50612150(CHEMBL5281161)
Affinity DataIC50: 1nMAssay Description:Inhibition of KLK7 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetKallikrein-7(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50429202(LYNGBYASTATIN 7)
Affinity DataIC50: 3.10nMAssay Description:Inhibition of human recombinant kallikrein 7 (23 to 252 residues) using MCA-RPKPVE-Nval-WRK(Dnp)-NH2 as substrate by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetNeutrophil elastase(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50084637(Sivelestat | 2,2-Dimethyl-propionic acid 4-[2-(car...)
Affinity DataIC50: 3.5nMAssay Description:Inhibition of elastase in human neutrophil using MeOSuc-AAPV-AMC as substrate by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetKallikrein-7(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50612149(CHEMBL5284383)
Affinity DataIC50: 5nMAssay Description:Inhibition of human recombinant kallikrein 7 (23 to 252 residues) using MCA-RPKPVE-Nval-WRK(Dnp)-NH2 as substrate by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetNeutrophil elastase(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50429202(LYNGBYASTATIN 7)
Affinity DataIC50: 28nMAssay Description:Inhibition of elastase in human neutrophil using N-(OMe-succinyl)-Ala-Ala-Pro-Val-p-nitroanilide as substrate preincubated with enzyme for 15 mins fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetNeutrophil elastase(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50612149(CHEMBL5284383)
Affinity DataIC50: 44nMAssay Description:Inhibition of elastase in human neutrophil using N-(OMe-succinyl)-Ala-Ala-Pro-Val-p-nitroanilide as substrate preincubated with enzyme for 15 mins fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetNeutrophil elastase(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50429201(CHEMBL2338554)
Affinity DataIC50: 93nMAssay Description:Inhibition of elastase in human neutrophil using N-(OMe-succinyl)-Ala-Ala-Pro-Val-p-nitroanilide as substrate preincubated with enzyme for 15 mins fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetNeutrophil elastase(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50084637(Sivelestat | 2,2-Dimethyl-propionic acid 4-[2-(car...)
Affinity DataIC50: 128nMAssay Description:Inhibition of elastase in human neutrophil using N-(OMe-succinyl)-Ala-Ala-Pro-Val-p-nitroanilide as substrate preincubated with enzyme for 15 mins fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetKallikrein-7(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50288832(CHEMBL1398351)
Affinity DataIC50: 2.84E+4nMAssay Description:Inhibition of human recombinant kallikrein 7 (23 to 252 residues) using MCA-RPKPVE-Nval-WRK(Dnp)-NH2 as substrate by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed