Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) with all data for entry = 50012908
TargetCannabinoid receptor 1(Human)
Therapeutics

Curated by ChEMBL
LigandPNGBDBM50389939(CHEMBL1553629)
Affinity DataIC50: 0.290nMAssay Description:Positive allosteric modulatory activity at C-terminal GFP-tagged human CB1R expressed in HEK293 cell membrane after 90 mins in presence of [3H]CP5594...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetNuclear receptor ROR-gamma(Human)
Therapeutics

Curated by ChEMBL
LigandPNGBDBM50106301(CHEMBL3598140)
Affinity DataIC50: 6nMAssay Description:Inhibition of His6-tagged human RORgammat LBD expressed in Escherichia coli BL21(DE3) cells after 16 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Human)
Therapeutics

Curated by ChEMBL
LigandPNGBDBM50106301(CHEMBL3598140)
Affinity DataIC50: 40nMAssay Description:Inhibition of RORgammat in human PBMC by IL17A assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed