Compile Data Set for Download or QSAR
Report error Found 25 Enz. Inhib. hit(s) with all data for entry = 50012915
TargetProstaglandin G/H synthase 2(Mouse)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50561580(CHEMBL4777544)
Affinity DataIC50: 22nMAssay Description:Inhibition of mouse COX2 using 2-arachidonylglycerol as substrate preincubated for 3 mins followed by substrate addition and measured for 30 sec by L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Mouse)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50561580(CHEMBL4777544)
Affinity DataIC50: 145nMAssay Description:Inhibition of mouse COX2 using arachidonic acid and 2-arachidonylglycerol as substrate preincubated for 5 mins followed by substrate addition and mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Mouse)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50561580(CHEMBL4777544)
Affinity DataIC50: 200nMAssay Description:Inhibition of mouse COX2 using [1-14C]AA as substrate preincubated for 20 mins followed by substrate addition and measured for 30 sec by thin layer c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Mouse)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50561583(CHEMBL4763221)
Affinity DataIC50: 800nMAssay Description:Inhibition of mouse COX2 using 2-arachidonylglycerol as substrate preincubated for 3 mins followed by substrate addition and measured for 30 sec by L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Mouse)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50561582(CHEMBL4749817)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of mouse COX2 using arachidonic acid as substrate preincubated for 3 mins followed by substrate addition and measured for 30 sec by LC/MS ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Mouse)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50561583(CHEMBL4763221)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of mouse COX2 using arachidonic acid as substrate preincubated for 3 mins followed by substrate addition and measured for 30 sec by LC/MS ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Mouse)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50561579(CHEMBL4784346)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of mouse COX2 using 2-arachidonylglycerol as substrate preincubated for 3 mins followed by substrate addition and measured for 30 sec by L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Mouse)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50132104(6-Methoxy-1-methyl-4,9-dihydro-3H-beta-carboline |...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of mouse COX2 using 2-arachidonylglycerol as substrate preincubated for 3 mins followed by substrate addition and measured for 30 sec by L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Mouse)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50561581(CHEMBL4758939)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of mouse COX2 using 2-arachidonylglycerol as substrate preincubated for 3 mins followed by substrate addition and measured for 30 sec by L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProstaglandin G/H synthase 2(Mouse)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50561582(CHEMBL4749817)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of mouse COX2 using 2-arachidonylglycerol as substrate preincubated for 3 mins followed by substrate addition and measured for 30 sec by L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Mouse)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50561579(CHEMBL4784346)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of mouse COX2 using arachidonic acid as substrate preincubated for 3 mins followed by substrate addition and measured for 30 sec by LC/MS ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Mouse)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50132104(6-Methoxy-1-methyl-4,9-dihydro-3H-beta-carboline |...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of mouse COX2 using arachidonic acid as substrate preincubated for 3 mins followed by substrate addition and measured for 30 sec by LC/MS ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Mouse)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50561580(CHEMBL4777544)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of mouse COX2 using arachidonic acid as substrate preincubated for 3 mins followed by substrate addition and measured for 30 sec by LC/MS ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Mouse)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50561581(CHEMBL4758939)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of mouse COX2 using arachidonic acid as substrate preincubated for 3 mins followed by substrate addition and measured for 30 sec by LC/MS ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProstaglandin G/H synthase 2(Mouse)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50561581(CHEMBL4758939)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of mouse COX2 using [1-14C]AA as substrate preincubated for 20 mins followed by substrate addition and measured for 30 sec by thin layer c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProstaglandin G/H synthase 1(Sheep)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50561583(CHEMBL4763221)
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of ovine COX1 using [1-14C]AA as substrate preincubated for 20 mins followed by substrate addition and measured for 30 sec by thin layer c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50561579(CHEMBL4784346)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of ovine COX1 using [1-14C]AA as substrate preincubated for 20 mins followed by substrate addition and measured for 30 sec by thin layer c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50132104(6-Methoxy-1-methyl-4,9-dihydro-3H-beta-carboline |...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of ovine COX1 using [1-14C]AA as substrate preincubated for 20 mins followed by substrate addition and measured for 30 sec by thin layer c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50561580(CHEMBL4777544)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of ovine COX1 using [1-14C]AA as substrate preincubated for 20 mins followed by substrate addition and measured for 30 sec by thin layer c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50561581(CHEMBL4758939)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of ovine COX1 using [1-14C]AA as substrate preincubated for 20 mins followed by substrate addition and measured for 30 sec by thin layer c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50561582(CHEMBL4749817)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of ovine COX1 using [1-14C]AA as substrate preincubated for 20 mins followed by substrate addition and measured for 30 sec by thin layer c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Mouse)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50561579(CHEMBL4784346)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of mouse COX2 using [1-14C]AA as substrate preincubated for 20 mins followed by substrate addition and measured for 30 sec by thin layer c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Mouse)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50132104(6-Methoxy-1-methyl-4,9-dihydro-3H-beta-carboline |...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of mouse COX2 using [1-14C]AA as substrate preincubated for 20 mins followed by substrate addition and measured for 30 sec by thin layer c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Mouse)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50561582(CHEMBL4749817)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of mouse COX2 using [1-14C]AA as substrate preincubated for 20 mins followed by substrate addition and measured for 30 sec by thin layer c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Mouse)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50561583(CHEMBL4763221)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of mouse COX2 using [1-14C]AA as substrate preincubated for 20 mins followed by substrate addition and measured for 30 sec by thin layer c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed