Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with all data for entry = 50012920
TargetBromodomain-containing protein 4(Human)
Rwth Aachen University

Curated by ChEMBL
LigandPNGBDBM50561594(CHEMBL4790505)
Affinity DataIC50: 500nMAssay Description:Inhibition of BRD4 in human HEL cells harboring JAK2 V617F mutant assessed as decrease in metabolic activity measured after 72 hrs by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
Rwth Aachen University

Curated by ChEMBL
LigandPNGBDBM50561594(CHEMBL4790505)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of BRD4 in human MOLM-14 cells harboring FLT3-ITD mutant assessed as decrease in metabolic activity measured after 72 hrs by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
Rwth Aachen University

Curated by ChEMBL
LigandPNGBDBM50399434(CHEMBL2179387)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of BRD4 in human HEL cells harboring JAK2 V617F mutant assessed as decrease in metabolic activity measured after 72 hrs by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetBromodomain-containing protein 4(Human)
Rwth Aachen University

Curated by ChEMBL
LigandPNGBDBM50399434(CHEMBL2179387)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of BRD4 in human MOLM-14 cells harboring FLT3-ITD mutant assessed as decrease in metabolic activity measured after 72 hrs by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)