Compile Data Set for Download or QSAR
Report error Found 15 Enz. Inhib. hit(s) with all data for entry = 50004934
TargetHigh affinity nerve growth factor receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM158154(US9029356, 11 | US9255087, 11 | US10081622, Compou...)
Affinity DataIC50: 1nMAssay Description:Inhibition of wild type TRAK (unknown origin) incubated for 30 mins by caliper mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHigh affinity nerve growth factor receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM374727(US10246466, Example 93 | (7S,13R)-11-fluoro-7,13-d...)
Affinity DataIC50: 1nMAssay Description:Inhibition of wild type TRAK (unknown origin) incubated for 30 mins by caliper mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHigh affinity nerve growth factor receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50507492(Loxo-195 | Selitrectinib | US10966985, Compound 33...)
Affinity DataIC50: 1nMAssay Description:Inhibition of wild type TRAK (unknown origin) incubated for 30 mins by caliper mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details Article
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50224533(CHEMBL5266269)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of wild type TRAK (unknown origin) incubated for 30 mins by caliper mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details Article
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM136597(US8865698, 14 | US10047097, 14 | US9676783, 14 | U...)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of wild type TRAK (unknown origin) incubated for 30 mins by caliper mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details Article
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50224532(CHEMBL5282675)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of wild type TRAK (unknown origin) incubated for 30 mins by caliper mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details Article
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50224528(CHEMBL5275171)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of wild type TRAK (unknown origin) incubated for 30 mins by caliper mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details Article
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50224527(CHEMBL5288589)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of wild type TRAK (unknown origin) incubated for 30 mins by caliper mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details Article
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50224529(CHEMBL5287060)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of wild type TRAK (unknown origin) incubated for 30 mins by caliper mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details Article
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50224553(CHEMBL5287063)
Affinity DataIC50: 2.80nMAssay Description:Inhibition of wild type TRAK (unknown origin) incubated for 30 mins by caliper mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details Article
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50224530(CHEMBL5291020)
Affinity DataIC50: 3nMAssay Description:Inhibition of wild type TRAK (unknown origin) incubated for 30 mins by caliper mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details Article
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50225315(CHEMBL5287847)
Affinity DataIC50: 3nMAssay Description:Inhibition of wild type TRAK (unknown origin) incubated for 30 mins by caliper mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details Article
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50224531(CHEMBL5275881)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of wild type TRAK (unknown origin) incubated for 30 mins by caliper mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details Article
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50224526(CHEMBL5271403)
Affinity DataIC50: 3.60nMAssay Description:Inhibition of wild type TRAK (unknown origin) incubated for 30 mins by caliper mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details Article
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50224552(CHEMBL5291305)
Affinity DataIC50: 8.40nMAssay Description:Inhibition of wild type TRAK (unknown origin) incubated for 30 mins by caliper mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details Article
PubMed