Compile Data Set for Download or QSAR
Report error Found 94 Enz. Inhib. hit(s) with all data for entry = 50011561
TargetAndrogen receptor(Rat)
University of Tennessee Health Science Center

Curated by ChEMBL
LigandPNGBDBM18161(DHT | Dihydrotestosterone | [3H]DHT | (5alpha,17be...)
Affinity DataIC50: 1nMAssay Description:Displacement of [3H]-MIB from wild-type rat AR LBD measured after 16 hrs by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAndrogen receptor(Rat)
University of Tennessee Health Science Center

Curated by ChEMBL
LigandPNGBDBM10884((2S,4S)-4-(ethylamino)-2-methyl-1,1-dioxo-2H,3H,4H...)
Affinity DataKi:  11nMAssay Description:Displacement of [3H]-MIB from wild-type rat AR LBD measured after 16 hrs by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
University of Tennessee Health Science Center

Curated by ChEMBL
LigandPNGBDBM50548630(CHEMBL4794467 | US11230523, Compound 1069)
Affinity DataIC50: 35nMAssay Description:Antagonist activity at recombinant human AR expressed in HEK293 cells assessed as inhibition of R1881-induced transcriptional activity measured after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
University of Tennessee Health Science Center

Curated by ChEMBL
LigandPNGBDBM468351(US10806720, Compound 1036 | US11230523, Compound 1...)
Affinity DataIC50: 36nMAssay Description:Antagonist activity at recombinant human AR expressed in HEK293 cells assessed as inhibition of R1881-induced transcriptional activity measured after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
University of Tennessee Health Science Center

Curated by ChEMBL
LigandPNGBDBM50548626(CHEMBL4776248)
Affinity DataIC50: 43nMAssay Description:Antagonist activity at recombinant human AR F876L mutant expressed in COS cells assessed as inhibition of R1881-induced transcriptional activity meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
University of Tennessee Health Science Center

Curated by ChEMBL
LigandPNGBDBM50548626(CHEMBL4776248)
Affinity DataIC50: 45nMAssay Description:Antagonist activity at recombinant human AR expressed in HEK293 cells assessed as inhibition of R1881-induced transcriptional activity measured after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
University of Tennessee Health Science Center

Curated by ChEMBL
LigandPNGBDBM50548634(CHEMBL4778795)
Affinity DataIC50: 59nMAssay Description:Antagonist activity at recombinant human AR expressed in HEK293 cells assessed as inhibition of R1881-induced transcriptional activity measured after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
University of Tennessee Health Science Center

Curated by ChEMBL
LigandPNGBDBM468341(US10806720, Compound 1022)
Affinity DataIC50: 62nMAssay Description:Antagonist activity at recombinant human AR expressed in HEK293 cells assessed as inhibition of R1881-induced transcriptional activity measured after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
University of Tennessee Health Science Center

Curated by ChEMBL
LigandPNGBDBM468341(US10806720, Compound 1022)
Affinity DataIC50: 63nMAssay Description:Antagonist activity at recombinant human AR F876L mutant expressed in COS cells assessed as inhibition of R1881-induced transcriptional activity meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
University of Tennessee Health Science Center

Curated by ChEMBL
LigandPNGBDBM10884((2S,4S)-4-(ethylamino)-2-methyl-1,1-dioxo-2H,3H,4H...)
Affinity DataIC50: 65nMAssay Description:Antagonist activity at recombinant human AR expressed in HEK293 cells assessed as inhibition of R1881-induced transcriptional activity measured after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
University of Tennessee Health Science Center

Curated by ChEMBL
LigandPNGBDBM468336(US10806720, Compound 1017 | US11230523, Compound 1...)
Affinity DataIC50: 71nMAssay Description:Antagonist activity at recombinant human AR expressed in HEK293 cells assessed as inhibition of R1881-induced transcriptional activity measured after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
University of Tennessee Health Science Center

Curated by ChEMBL
LigandPNGBDBM468362(US10806720, Compound 1058 | US11230523, Compound 1...)
Affinity DataIC50: 84nMAssay Description:Antagonist activity at recombinant human AR expressed in HEK293 cells assessed as inhibition of R1881-induced transcriptional activity measured after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
University of Tennessee Health Science Center

Curated by ChEMBL
LigandPNGBDBM468362(US10806720, Compound 1058 | US11230523, Compound 1...)
Affinity DataIC50: 84nMAssay Description:Antagonist activity at recombinant human AR F876L mutant expressed in COS cells assessed as inhibition of R1881-induced transcriptional activity meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetAndrogen receptor(Rat)
University of Tennessee Health Science Center

Curated by ChEMBL
LigandPNGBDBM50548634(CHEMBL4778795)
Affinity DataKi:  89nMAssay Description:Displacement of [3H]-MIB from wild-type rat AR LBD measured after 16 hrs by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
University of Tennessee Health Science Center

Curated by ChEMBL
LigandPNGBDBM50548640(CHEMBL4752991)
Affinity DataIC50: 136nMAssay Description:Antagonist activity at recombinant human AR expressed in HEK293 cells assessed as inhibition of R1881-induced transcriptional activity measured after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
University of Tennessee Health Science Center

Curated by ChEMBL
LigandPNGBDBM50548631(CHEMBL4757702)
Affinity DataIC50: 138nMAssay Description:Antagonist activity at recombinant human AR expressed in HEK293 cells assessed as inhibition of R1881-induced transcriptional activity measured after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
University of Tennessee Health Science Center

Curated by ChEMBL
LigandPNGBDBM50094975(US10053433, ARN-509 | ARN-509 | JNJ-56021927 | apa...)
Affinity DataIC50: 160nMAssay Description:Antagonist activity at recombinant human AR expressed in HEK293 cells assessed as inhibition of R1881-induced transcriptional activity measured after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
University of Tennessee Health Science Center

Curated by ChEMBL
LigandPNGBDBM50548633(CHEMBL4739997 | US11230523, Compound 1060)
Affinity DataIC50: 181nMAssay Description:Antagonist activity at recombinant human AR expressed in HEK293 cells assessed as inhibition of R1881-induced transcriptional activity measured after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
University of Tennessee Health Science Center

Curated by ChEMBL
LigandPNGBDBM468339(US10806720, Compound 1020 | US11648234, Compound 1...)
Affinity DataIC50: 192nMAssay Description:Antagonist activity at recombinant human AR expressed in HEK293 cells assessed as inhibition of R1881-induced transcriptional activity measured after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
University of Tennessee Health Science Center

Curated by ChEMBL
LigandPNGBDBM468322(US10806720, Compound 1002 | US11648234, Compound 1...)
Affinity DataIC50: 199nMAssay Description:Antagonist activity at recombinant human AR expressed in HEK293 cells assessed as inhibition of R1881-induced transcriptional activity measured after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetAndrogen receptor(Rat)
University of Tennessee Health Science Center

Curated by ChEMBL
LigandPNGBDBM50548633(CHEMBL4739997 | US11230523, Compound 1060)
Affinity DataKi:  202nMAssay Description:Displacement of [3H]-MIB from wild-type rat AR LBD measured after 16 hrs by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
University of Tennessee Health Science Center

Curated by ChEMBL
LigandPNGBDBM468333(US10806720, Compound 1014 | US11230523, Compound 1...)
Affinity DataIC50: 205nMAssay Description:Antagonist activity at recombinant human AR expressed in HEK293 cells assessed as inhibition of R1881-induced transcriptional activity measured after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
University of Tennessee Health Science Center

Curated by ChEMBL
LigandPNGBDBM468356(US10806720, Compound 1043 | US11648234, Compound 1...)
Affinity DataIC50: 208nMAssay Description:Antagonist activity at recombinant human AR expressed in HEK293 cells assessed as inhibition of R1881-induced transcriptional activity measured after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
University of Tennessee Health Science Center

Curated by ChEMBL
LigandPNGBDBM50425732(Xtandi | ENZALUTAMIDE | US10053433, FC 4.129 | US1...)
Affinity DataIC50: 216nMAssay Description:Antagonist activity at recombinant human AR expressed in HEK293 cells assessed as inhibition of R1881-induced transcriptional activity measured after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
University of Tennessee Health Science Center

Curated by ChEMBL
LigandPNGBDBM468322(US10806720, Compound 1002 | US11648234, Compound 1...)
Affinity DataIC50: 219nMAssay Description:Antagonist activity at recombinant human AR F876L mutant expressed in COS cells assessed as inhibition of R1881-induced transcriptional activity meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
University of Tennessee Health Science Center

Curated by ChEMBL
LigandPNGBDBM468331(US10806720, Compound 1012 | US11230523, Compound 1...)
Affinity DataIC50: 220nMAssay Description:Antagonist activity at recombinant human AR expressed in HEK293 cells assessed as inhibition of R1881-induced transcriptional activity measured after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetAndrogen receptor(Rat)
University of Tennessee Health Science Center

Curated by ChEMBL
LigandPNGBDBM50548645(CHEMBL4777131)
Affinity DataKi:  223nMAssay Description:Displacement of [3H]-MIB from wild-type rat AR LBD measured after 16 hrs by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
University of Tennessee Health Science Center

Curated by ChEMBL
LigandPNGBDBM468341(US10806720, Compound 1022)
Affinity DataIC50: 235nMAssay Description:Antagonist activity at recombinant human PR expressed in COS cells assessed as inhibition of R1881-induced transcriptional activity measured after 24...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
University of Tennessee Health Science Center

Curated by ChEMBL
LigandPNGBDBM50548635(CHEMBL4740742)
Affinity DataIC50: 248nMAssay Description:Antagonist activity at recombinant human AR expressed in HEK293 cells assessed as inhibition of R1881-induced transcriptional activity measured after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
University of Tennessee Health Science Center

Curated by ChEMBL
LigandPNGBDBM50548638(CHEMBL4794197)
Affinity DataIC50: 276nMAssay Description:Antagonist activity at recombinant human AR expressed in HEK293 cells assessed as inhibition of R1881-induced transcriptional activity measured after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
University of Tennessee Health Science Center

Curated by ChEMBL
LigandPNGBDBM468363(US10806720, Compound 1059 | US11230523, Compound 1...)
Affinity DataIC50: 285nMAssay Description:Antagonist activity at recombinant human AR expressed in HEK293 cells assessed as inhibition of R1881-induced transcriptional activity measured after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
University of Tennessee Health Science Center

Curated by ChEMBL
LigandPNGBDBM50548632(CHEMBL4752477 | US11230523, Compound 1061)
Affinity DataIC50: 332nMAssay Description:Antagonist activity at recombinant human AR expressed in HEK293 cells assessed as inhibition of R1881-induced transcriptional activity measured after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
University of Tennessee Health Science Center

Curated by ChEMBL
LigandPNGBDBM468322(US10806720, Compound 1002 | US11648234, Compound 1...)
Affinity DataIC50: 403nMAssay Description:Antagonist activity at recombinant human PR expressed in COS cells assessed as inhibition of R1881-induced transcriptional activity measured after 24...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
University of Tennessee Health Science Center

Curated by ChEMBL
LigandPNGBDBM468327(US10806720, Compound 1007 | US11648234, Compound 1...)
Affinity DataIC50: 427nMAssay Description:Antagonist activity at recombinant human AR expressed in HEK293 cells assessed as inhibition of R1881-induced transcriptional activity measured after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
University of Tennessee Health Science Center

Curated by ChEMBL
LigandPNGBDBM468359(US10806720, Compound 1050 | US11230523, Compound 1...)
Affinity DataIC50: 427nMAssay Description:Antagonist activity at recombinant human AR expressed in HEK293 cells assessed as inhibition of R1881-induced transcriptional activity measured after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
University of Tennessee Health Science Center

Curated by ChEMBL
LigandPNGBDBM468342(US10806720, Compound 1024 | US11648234, Compound 1...)
Affinity DataIC50: 462nMAssay Description:Antagonist activity at recombinant human AR expressed in HEK293 cells assessed as inhibition of R1881-induced transcriptional activity measured after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetAndrogen receptor(Rat)
University of Tennessee Health Science Center

Curated by ChEMBL
LigandPNGBDBM50548635(CHEMBL4740742)
Affinity DataKi:  509nMAssay Description:Displacement of [3H]-MIB from wild-type rat AR LBD measured after 16 hrs by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetAndrogen receptor(Rat)
University of Tennessee Health Science Center

Curated by ChEMBL
LigandPNGBDBM468333(US10806720, Compound 1014 | US11230523, Compound 1...)
Affinity DataKi:  512nMAssay Description:Displacement of [3H]-MIB from wild-type rat AR LBD measured after 16 hrs by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetAndrogen receptor(Rat)
University of Tennessee Health Science Center

Curated by ChEMBL
LigandPNGBDBM50548630(CHEMBL4794467 | US11230523, Compound 1069)
Affinity DataKi:  567nMAssay Description:Displacement of [3H]-MIB from wild-type rat AR LBD measured after 16 hrs by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
University of Tennessee Health Science Center

Curated by ChEMBL
LigandPNGBDBM50548628(CHEMBL4758119)
Affinity DataIC50: 579nMAssay Description:Antagonist activity at recombinant human AR expressed in HEK293 cells assessed as inhibition of R1881-induced transcriptional activity measured after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetAndrogen receptor(Rat)
University of Tennessee Health Science Center

Curated by ChEMBL
LigandPNGBDBM468363(US10806720, Compound 1059 | US11230523, Compound 1...)
Affinity DataKi:  601nMAssay Description:Displacement of [3H]-MIB from wild-type rat AR LBD measured after 16 hrs by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetAndrogen receptor(Rat)
University of Tennessee Health Science Center

Curated by ChEMBL
LigandPNGBDBM468362(US10806720, Compound 1058 | US11230523, Compound 1...)
Affinity DataKi:  607nMAssay Description:Displacement of [3H]-MIB from wild-type rat AR LBD measured after 16 hrs by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetAndrogen receptor(Rat)
University of Tennessee Health Science Center

Curated by ChEMBL
LigandPNGBDBM468343(US10806720, Compound 1025 | US11230523, Compound 1...)
Affinity DataKi:  612nMAssay Description:Displacement of [3H]-MIB from wild-type rat AR LBD measured after 16 hrs by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
University of Tennessee Health Science Center

Curated by ChEMBL
LigandPNGBDBM468350(US10806720, Compound 1035 | US11648234, Compound 1...)
Affinity DataIC50: 758nMAssay Description:Antagonist activity at recombinant human AR expressed in HEK293 cells assessed as inhibition of R1881-induced transcriptional activity measured after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetAndrogen receptor(Rat)
University of Tennessee Health Science Center

Curated by ChEMBL
LigandPNGBDBM468331(US10806720, Compound 1012 | US11230523, Compound 1...)
Affinity DataKi:  821nMAssay Description:Displacement of [3H]-MIB from wild-type rat AR LBD measured after 16 hrs by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
University of Tennessee Health Science Center

Curated by ChEMBL
LigandPNGBDBM50548636(CHEMBL4741767)
Affinity DataIC50: 827nMAssay Description:Antagonist activity at recombinant human AR expressed in HEK293 cells assessed as inhibition of R1881-induced transcriptional activity measured after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetAndrogen receptor(Rat)
University of Tennessee Health Science Center

Curated by ChEMBL
LigandPNGBDBM468336(US10806720, Compound 1017 | US11230523, Compound 1...)
Affinity DataKi:  898nMAssay Description:Displacement of [3H]-MIB from wild-type rat AR LBD measured after 16 hrs by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
University of Tennessee Health Science Center

Curated by ChEMBL
LigandPNGBDBM468348(US10806720, Compound 1032 | US11648234, Compound 1...)
Affinity DataIC50: 901nMAssay Description:Antagonist activity at recombinant human AR expressed in HEK293 cells assessed as inhibition of R1881-induced transcriptional activity measured after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
University of Tennessee Health Science Center

Curated by ChEMBL
LigandPNGBDBM468343(US10806720, Compound 1025 | US11230523, Compound 1...)
Affinity DataIC50: 969nMAssay Description:Antagonist activity at recombinant human AR expressed in HEK293 cells assessed as inhibition of R1881-induced transcriptional activity measured after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetAndrogen receptor(Rat)
University of Tennessee Health Science Center

Curated by ChEMBL
LigandPNGBDBM468350(US10806720, Compound 1035 | US11648234, Compound 1...)
Affinity DataKi:  1.06E+3nMAssay Description:Displacement of [3H]-MIB from wild-type rat AR LBD measured after 16 hrs by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
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