Compile Data Set for Download or QSAR
Report error Found 27 Enz. Inhib. hit(s) with all data for entry = 50012338
TargetTyrosine-protein kinase JAK3(Human)
Xuzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50243388(AT-9283 | US10981896, Compound AT9283)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of JAK3 (unknown origin) incubated for 40 mins in presence of ATP by Kinase-glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Xuzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50243388(AT-9283 | US10981896, Compound AT9283)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of JAK2 (unknown origin) incubated for 40 mins in presence of ATP by Kinase-glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetTyrosine-protein kinase JAK2(Human)
Xuzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50556682(CHEMBL4794655)
Affinity DataIC50: 8nMAssay Description:Inhibition of JAK2 (unknown origin) incubated for 40 mins in presence of ATP by Kinase-glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Xuzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50556681(CHEMBL4795804)
Affinity DataIC50: 13nMAssay Description:Inhibition of JAK3 (unknown origin) incubated for 40 mins in presence of ATP by Kinase-glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Xuzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50556677(CHEMBL4782433)
Affinity DataIC50: 14nMAssay Description:Inhibition of JAK2 (unknown origin) incubated for 40 mins in presence of ATP by Kinase-glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Xuzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50556681(CHEMBL4795804)
Affinity DataIC50: 16nMAssay Description:Inhibition of JAK2 (unknown origin) incubated for 40 mins in presence of ATP by Kinase-glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Xuzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50556682(CHEMBL4794655)
Affinity DataIC50: 23nMAssay Description:Inhibition of JAK3 (unknown origin) incubated for 40 mins in presence of ATP by Kinase-glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Xuzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50556677(CHEMBL4782433)
Affinity DataIC50: 24nMAssay Description:Inhibition of JAK3 (unknown origin) incubated for 40 mins in presence of ATP by Kinase-glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Xuzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50243388(AT-9283 | US10981896, Compound AT9283)
Affinity DataIC50: 26nMAssay Description:Inhibition of Aurora A (unknown origin) incubated for 40 mins in presence of ATP by Kinase-glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetTyrosine-protein kinase JAK3(Human)
Xuzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50556680(CHEMBL4758261)
Affinity DataIC50: 57nMAssay Description:Inhibition of JAK3 (unknown origin) incubated for 40 mins in presence of ATP by Kinase-glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Xuzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50243388(AT-9283 | US10981896, Compound AT9283)
Affinity DataIC50: 62nMAssay Description:Inhibition of Aurora B (unknown origin) incubated for 40 mins in presence of ATP by Kinase-glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Xuzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50556679(CHEMBL4763483)
Affinity DataIC50: 64nMAssay Description:Inhibition of JAK3 (unknown origin) incubated for 40 mins in presence of ATP by Kinase-glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Xuzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50556679(CHEMBL4763483)
Affinity DataIC50: 94nMAssay Description:Inhibition of JAK2 (unknown origin) incubated for 40 mins in presence of ATP by Kinase-glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Xuzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50556682(CHEMBL4794655)
Affinity DataIC50: 145nMAssay Description:Inhibition of Aurora A (unknown origin) incubated for 40 mins in presence of ATP by Kinase-glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Xuzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50556680(CHEMBL4758261)
Affinity DataIC50: 166nMAssay Description:Inhibition of JAK2 (unknown origin) incubated for 40 mins in presence of ATP by Kinase-glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Xuzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50556677(CHEMBL4782433)
Affinity DataIC50: 359nMAssay Description:Inhibition of Aurora A (unknown origin) incubated for 40 mins in presence of ATP by Kinase-glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Xuzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50556678(CHEMBL4744513)
Affinity DataIC50: 466nMAssay Description:Inhibition of Aurora A (unknown origin) incubated for 40 mins in presence of ATP by Kinase-glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Xuzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50556678(CHEMBL4744513)
Affinity DataIC50: 569nMAssay Description:Inhibition of JAK3 (unknown origin) incubated for 40 mins in presence of ATP by Kinase-glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Xuzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50556680(CHEMBL4758261)
Affinity DataIC50: 583nMAssay Description:Inhibition of Aurora B (unknown origin) incubated for 40 mins in presence of ATP by Kinase-glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Xuzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50556678(CHEMBL4744513)
Affinity DataIC50: 650nMAssay Description:Inhibition of Aurora B (unknown origin) incubated for 40 mins in presence of ATP by Kinase-glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Xuzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50556680(CHEMBL4758261)
Affinity DataIC50: 939nMAssay Description:Inhibition of Aurora A (unknown origin) incubated for 40 mins in presence of ATP by Kinase-glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Xuzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50556677(CHEMBL4782433)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of Aurora B (unknown origin) incubated for 40 mins in presence of ATP by Kinase-glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Xuzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50556681(CHEMBL4795804)
Affinity DataIC50: 1.13E+3nMAssay Description:Inhibition of Aurora A (unknown origin) incubated for 40 mins in presence of ATP by Kinase-glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Xuzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50556678(CHEMBL4744513)
Affinity DataIC50: 1.18E+3nMAssay Description:Inhibition of JAK2 (unknown origin) incubated for 40 mins in presence of ATP by Kinase-glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Xuzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50556683(CHEMBL4750823)
Affinity DataIC50: 1.52E+3nMAssay Description:Inhibition of Aurora A (unknown origin) incubated for 40 mins in presence of ATP by Kinase-glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Xuzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50556684(CHEMBL4797744)
Affinity DataIC50: 2.06E+3nMAssay Description:Inhibition of Aurora A (unknown origin) incubated for 40 mins in presence of ATP by Kinase-glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Xuzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50556679(CHEMBL4763483)
Affinity DataIC50: 2.51E+3nMAssay Description:Inhibition of Aurora A (unknown origin) incubated for 40 mins in presence of ATP by Kinase-glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed