Compile Data Set for Download or QSAR
Report error Found 23 Enz. Inhib. hit(s) with all data for entry = 50012134
TargetFocal adhesion kinase 1(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50554439(CHEMBL4752642)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of recombinant human N-terminal His-tagged FAK (393 to 698 residues) expressed in baculovirus infected Sf9 insect cells using Poly (4:1 Gl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetFocal adhesion kinase 1(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50554449(CHEMBL4750273)
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant human N-terminal His-tagged FAK (393 to 698 residues) expressed in baculovirus infected Sf9 insect cells using Poly (4:1 Gl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetFocal adhesion kinase 1(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50554448(CHEMBL4783568)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of recombinant human N-terminal His-tagged FAK (393 to 698 residues) expressed in baculovirus infected Sf9 insect cells using Poly (4:1 Gl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetFocal adhesion kinase 1(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50554447(CHEMBL4796523)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of recombinant human N-terminal His-tagged FAK (393 to 698 residues) expressed in baculovirus infected Sf9 insect cells using Poly (4:1 Gl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetFocal adhesion kinase 1(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50554441(CHEMBL4788979)
Affinity DataIC50: 3.70nMAssay Description:Inhibition of recombinant human N-terminal His-tagged FAK (393 to 698 residues) expressed in baculovirus infected Sf9 insect cells using Poly (4:1 Gl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetFocal adhesion kinase 1(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50554442(CHEMBL4746264)
Affinity DataIC50: 4.60nMAssay Description:Inhibition of recombinant human N-terminal His-tagged FAK (393 to 698 residues) expressed in baculovirus infected Sf9 insect cells using Poly (4:1 Gl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetFocal adhesion kinase 1(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50554443(CHEMBL4739917)
Affinity DataIC50: 4.90nMAssay Description:Inhibition of recombinant human N-terminal His-tagged FAK (393 to 698 residues) expressed in baculovirus infected Sf9 insect cells using Poly (4:1 Gl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetFocal adhesion kinase 1(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50334594(2-(5-chloro-2-(2-methoxy-4-morpholinophenylamino)p...)
Affinity DataIC50: 5.40nMAssay Description:Inhibition of GST-tagged recombinant FAK (unknown origin) expressed in baculovirus expression system incubated for 15-45 mins in presence of [gamma32...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetFocal adhesion kinase 1(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50554445(CHEMBL4751164)
Affinity DataIC50: 5.5nMAssay Description:Inhibition of recombinant human N-terminal His-tagged FAK (393 to 698 residues) expressed in baculovirus infected Sf9 insect cells using Poly (4:1 Gl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetFocal adhesion kinase 1(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50554440(CHEMBL4764885)
Affinity DataIC50: 5.60nMAssay Description:Inhibition of recombinant human N-terminal His-tagged FAK (393 to 698 residues) expressed in baculovirus infected Sf9 insect cells using Poly (4:1 Gl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetFocal adhesion kinase 1(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50334594(2-(5-chloro-2-(2-methoxy-4-morpholinophenylamino)p...)
Affinity DataIC50: 5.80nMAssay Description:Inhibition of recombinant human N-terminal His-tagged FAK (393 to 698 residues) expressed in baculovirus infected Sf9 insect cells using Poly (4:1 Gl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetFocal adhesion kinase 1(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50554446(CHEMBL4777260)
Affinity DataIC50: 6.80nMAssay Description:Inhibition of recombinant human N-terminal His-tagged FAK (393 to 698 residues) expressed in baculovirus infected Sf9 insect cells using Poly (4:1 Gl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetFocal adhesion kinase 1(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50554444(CHEMBL4792798)
Affinity DataIC50: 16nMAssay Description:Inhibition of recombinant human N-terminal His-tagged FAK (393 to 698 residues) expressed in baculovirus infected Sf9 insect cells using Poly (4:1 Gl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetInsulin receptor(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50334594(2-(5-chloro-2-(2-methoxy-4-morpholinophenylamino)p...)
Affinity DataIC50: 43nMAssay Description:Inhibition of GST-tagged recombinant INSR (unknown origin) expressed in baculovirus expression system incubated for 15-45 mins in presence of [gamma3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50334594(2-(5-chloro-2-(2-methoxy-4-morpholinophenylamino)p...)
Affinity DataIC50: 81nMAssay Description:Inhibition of GST-tagged recombinant IGFR1 (unknown origin) expressed in baculovirus expression system incubated for 15-45 mins in presence of [gamma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50334594(2-(5-chloro-2-(2-methoxy-4-morpholinophenylamino)p...)
Affinity DataIC50: 550nMAssay Description:Inhibition of GST-tagged recombinant HER1 (unknown origin) expressed in baculovirus expression system incubated for 15-45 mins in presence of [gamma3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50334594(2-(5-chloro-2-(2-methoxy-4-morpholinophenylamino)p...)
Affinity DataIC50: 710nMAssay Description:Inhibition of GST-tagged recombinant HER2 (unknown origin) expressed in baculovirus expression system incubated for 15-45 mins in presence of [gamma3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50334594(2-(5-chloro-2-(2-methoxy-4-morpholinophenylamino)p...)
Affinity DataIC50: 750nMAssay Description:Inhibition of GST-tagged recombinant FGFR1 (unknown origin) expressed in baculovirus expression system incubated for 15-45 mins in presence of [gamma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50334594(2-(5-chloro-2-(2-methoxy-4-morpholinophenylamino)p...)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of GST-tagged recombinant PDGFRbeta (unknown origin) expressed in baculovirus expression system incubated for 15-45 mins in presence of [g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetFocal adhesion kinase 1(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50554439(CHEMBL4752642)
Affinity DataKi:  0.230nMAssay Description:Covalent inhibition of recombinant human N-terminal His-tagged FAK (393 to 698 residues) expressed in baculovirus infected Sf9 insect cells using Pol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetFocal adhesion kinase 1(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50554449(CHEMBL4750273)
Affinity DataKi:  0.400nMAssay Description:Covalent inhibition of recombinant human N-terminal His-tagged FAK (393 to 698 residues) expressed in baculovirus infected Sf9 insect cells using Pol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetFocal adhesion kinase 1(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50554448(CHEMBL4783568)
Affinity DataKi:  0.470nMAssay Description:Covalent inhibition of recombinant human N-terminal His-tagged FAK (393 to 698 residues) expressed in baculovirus infected Sf9 insect cells using Pol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetFocal adhesion kinase 1(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50554446(CHEMBL4777260)
Affinity DataKi:  2.60nMAssay Description:Covalent inhibition of recombinant human N-terminal His-tagged FAK (393 to 698 residues) expressed in baculovirus infected Sf9 insect cells using Pol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed