Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) with all data for entry = 50013047
TargetNEDD8-activating enzyme E1 regulatory subunit(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50285607(MLN-4924 | MLN-4924003 | Pevonedistat)
Affinity DataIC50: 180nMAssay Description:Inhibition of NAE (unknown origin)-mediated neddylation assessed as suppression of cullin1-Nedd8 adduct formation preincubated for 10 mins followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetNEDD8-activating enzyme E1 regulatory subunit(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50562350(CHEMBL4788522)
Affinity DataIC50: 5.51E+3nMAssay Description:Inhibition of NAE (unknown origin)-mediated neddylation assessed as suppression of cullin1-Nedd8 adduct formation preincubated for 10 mins followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetNEDD8-activating enzyme E1 regulatory subunit(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50562351(CHEMBL4746177)
Affinity DataIC50: 6.67E+3nMAssay Description:Inhibition of NAE (unknown origin)-mediated neddylation assessed as suppression of cullin1-Nedd8 adduct formation preincubated for 10 mins followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetNEDD8-activating enzyme E1 regulatory subunit(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50562352(CHEMBL4744561)
Affinity DataIC50: 9.94E+3nMAssay Description:Inhibition of NAE (unknown origin)-mediated neddylation assessed as suppression of cullin1-Nedd8 adduct formation preincubated for 10 mins followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetNEDD8-activating enzyme E1 regulatory subunit(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50318907(CHEMBL1014 | TCV-116 | candesartancilexetil | Atac...)
Affinity DataIC50: 1.64E+4nMAssay Description:Inhibition of NAE (unknown origin)-mediated neddylation assessed as suppression of cullin1-Nedd8 adduct formation preincubated for 10 mins followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed