Compile Data Set for Download or QSAR
Report error Found 47 Enz. Inhib. hit(s) with all data for entry = 50012159
TargetDelta-type opioid receptor(Human)
St Louis College of Pharmacy and Washington University

Curated by ChEMBL
LigandPNGBDBM50554766(CHEMBL4795492)
Affinity DataEC50:  172nMAssay Description:Agonist activity at EA-fragment beta-arrestin-tagged human DOR expressed in human U2OS cell membranes assessed as stimulation of [35S]-GTPgammaS bind...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetDelta-type/Mu-type opioid receptor(Mouse)
St Louis College of Pharmacy and Washington University

Curated by ChEMBL
LigandPNGBDBM50554766(CHEMBL4795492)
Affinity DataEC50:  0.0320nMAssay Description:Agonist activity at MOR/DOR in wild-type C57BL6 mouse spinal cord membranes assessed as stimulation of [35S]-GTPgammaS binding measured after 60 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetDelta-type/Mu-type opioid receptor(Mouse)
St Louis College of Pharmacy and Washington University

Curated by ChEMBL
LigandPNGBDBM50554766(CHEMBL4795492)
Affinity DataEC50:  0.0316nMAssay Description:Agonist activity at MOR/DOR in wild-type C57BL6 mouse spinal cord membranes assessed as stimulation of [35S]-GTPgammaS binding measured after 60 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
St Louis College of Pharmacy and Washington University

Curated by ChEMBL
LigandPNGBDBM21015([tyrosyl-3,5-3H(N)]-D-Ala2-Mephe4-glyol5-enkephali...)
Affinity DataEC50:  83nMAssay Description:Agonist activity at EA-fragment beta-arrestin-tagged human MOR expressed in human U2OS cell membranes assessed as stimulation beta-arrestin recruitme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
St Louis College of Pharmacy and Washington University

Curated by ChEMBL
LigandPNGBDBM83396(ethyl 1-[(4-acetamidophenyl)methyl]-4-(2-phenyleth...)
Affinity DataEC50:  945nMAssay Description:Agonist activity at EA-fragment beta-arrestin-tagged human MOR expressed in human U2OS cell membranes assessed as stimulation beta-arrestin recruitme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
St Louis College of Pharmacy and Washington University

Curated by ChEMBL
LigandPNGBDBM50554762(CHEMBL4760974)
Affinity DataEC50:  426nMAssay Description:Agonist activity at EA-fragment beta-arrestin-tagged human MOR expressed in human U2OS cell membranes assessed as stimulation beta-arrestin recruitme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
St Louis College of Pharmacy and Washington University

Curated by ChEMBL
LigandPNGBDBM50554763(CHEMBL4758061)
Affinity DataEC50:  2.65E+3nMAssay Description:Agonist activity at EA-fragment beta-arrestin-tagged human MOR expressed in human U2OS cell membranes assessed as stimulation beta-arrestin recruitme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
St Louis College of Pharmacy and Washington University

Curated by ChEMBL
LigandPNGBDBM50554764(CHEMBL4761310)
Affinity DataEC50:  2.15E+3nMAssay Description:Agonist activity at EA-fragment beta-arrestin-tagged human MOR expressed in human U2OS cell membranes assessed as stimulation beta-arrestin recruitme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
St Louis College of Pharmacy and Washington University

Curated by ChEMBL
LigandPNGBDBM50554766(CHEMBL4795492)
Affinity DataEC50:  119nMAssay Description:Agonist activity at EA-fragment beta-arrestin-tagged human MOR expressed in human U2OS cell membranes assessed as stimulation beta-arrestin recruitme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
St Louis College of Pharmacy and Washington University

Curated by ChEMBL
LigandPNGBDBM50554770(CHEMBL4783653)
Affinity DataEC50:  605nMAssay Description:Agonist activity at EA-fragment beta-arrestin-tagged human MOR expressed in human U2OS cell membranes assessed as stimulation beta-arrestin recruitme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
St Louis College of Pharmacy and Washington University

Curated by ChEMBL
LigandPNGBDBM50000507(Tyr-D-Ala-Phe-Glu-Val-Val-GlyNH2 | 4-(2-{2-[2-Amin...)
Affinity DataEC50:  11nMAssay Description:Agonist activity at EA-fragment beta-arrestin-tagged human DOR expressed in human U2OS cell membranes assessed as stimulation of [35S]-GTPgammaS bind...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
St Louis College of Pharmacy and Washington University

Curated by ChEMBL
LigandPNGBDBM50554765(CHEMBL4781906)
Affinity DataEC50:  61nMAssay Description:Agonist activity at EA-fragment beta-arrestin-tagged human DOR expressed in human U2OS cell membranes assessed as stimulation of [35S]-GTPgammaS bind...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetDelta-type/Mu-type opioid receptor(Mouse)
St Louis College of Pharmacy and Washington University

Curated by ChEMBL
LigandPNGBDBM50000507(Tyr-D-Ala-Phe-Glu-Val-Val-GlyNH2 | 4-(2-{2-[2-Amin...)
Affinity DataEC50:  1.80nMAssay Description:Agonist activity at MOR/DOR in wild-type C57BL6 mouse spinal cord membranes assessed as stimulation of [35S]-GTPgammaS binding measured after 60 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
St Louis College of Pharmacy and Washington University

Curated by ChEMBL
LigandPNGBDBM50554770(CHEMBL4783653)
Affinity DataEC50:  3.33E+3nMAssay Description:Agonist activity at EA-fragment beta-arrestin-tagged human DOR expressed in human U2OS cell membranes assessed as stimulation of [35S]-GTPgammaS bind...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
St Louis College of Pharmacy and Washington University

Curated by ChEMBL
LigandPNGBDBM50554774(CHEMBL4755700)
Affinity DataEC50:  1.02E+3nMAssay Description:Agonist activity at EA-fragment beta-arrestin-tagged human DOR expressed in human U2OS cell membranes assessed as stimulation of [35S]-GTPgammaS bind...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
St Louis College of Pharmacy and Washington University

Curated by ChEMBL
LigandPNGBDBM50554775(CHEMBL4784650)
Affinity DataEC50:  93nMAssay Description:Agonist activity at EA-fragment beta-arrestin-tagged human DOR expressed in human U2OS cell membranes assessed as stimulation of [35S]-GTPgammaS bind...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
St Louis College of Pharmacy and Washington University

Curated by ChEMBL
LigandPNGBDBM50554776(CHEMBL4751847)
Affinity DataEC50:  374nMAssay Description:Agonist activity at EA-fragment beta-arrestin-tagged human DOR expressed in human U2OS cell membranes assessed as stimulation of [35S]-GTPgammaS bind...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
St Louis College of Pharmacy and Washington University

Curated by ChEMBL
LigandPNGBDBM50554777(CHEMBL4751491)
Affinity DataEC50:  659nMAssay Description:Agonist activity at EA-fragment beta-arrestin-tagged human DOR expressed in human U2OS cell membranes assessed as stimulation of [35S]-GTPgammaS bind...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
St Louis College of Pharmacy and Washington University

Curated by ChEMBL
LigandPNGBDBM50554778(CHEMBL4740220)
Affinity DataEC50:  288nMAssay Description:Agonist activity at EA-fragment beta-arrestin-tagged human DOR expressed in human U2OS cell membranes assessed as stimulation of [35S]-GTPgammaS bind...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
St Louis College of Pharmacy and Washington University

Curated by ChEMBL
LigandPNGBDBM83396(ethyl 1-[(4-acetamidophenyl)methyl]-4-(2-phenyleth...)
Affinity DataEC50:  812nMAssay Description:Agonist activity at EA-fragment beta-arrestin-tagged human DOR expressed in human U2OS cell membranes assessed as stimulation beta-arrestin recruitme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
St Louis College of Pharmacy and Washington University

Curated by ChEMBL
LigandPNGBDBM50000507(Tyr-D-Ala-Phe-Glu-Val-Val-GlyNH2 | 4-(2-{2-[2-Amin...)
Affinity DataEC50:  8nMAssay Description:Agonist activity at EA-fragment beta-arrestin-tagged human DOR expressed in human U2OS cell membranes assessed as stimulation beta-arrestin recruitme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
St Louis College of Pharmacy and Washington University

Curated by ChEMBL
LigandPNGBDBM50554765(CHEMBL4781906)
Affinity DataEC50:  509nMAssay Description:Agonist activity at EA-fragment beta-arrestin-tagged human DOR expressed in human U2OS cell membranes assessed as stimulation beta-arrestin recruitme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
St Louis College of Pharmacy and Washington University

Curated by ChEMBL
LigandPNGBDBM50554766(CHEMBL4795492)
Affinity DataEC50:  960nMAssay Description:Agonist activity at EA-fragment beta-arrestin-tagged human DOR expressed in human U2OS cell membranes assessed as stimulation beta-arrestin recruitme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
St Louis College of Pharmacy and Washington University

Curated by ChEMBL
LigandPNGBDBM50554769(CHEMBL4788377)
Affinity DataEC50:  1.30E+3nMAssay Description:Agonist activity at EA-fragment beta-arrestin-tagged human DOR expressed in human U2OS cell membranes assessed as stimulation beta-arrestin recruitme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
St Louis College of Pharmacy and Washington University

Curated by ChEMBL
LigandPNGBDBM50554771(CHEMBL4784041)
Affinity DataEC50:  70nMAssay Description:Agonist activity at EA-fragment beta-arrestin-tagged human MOR expressed in human U2OS cell membranes assessed as stimulation of [35S]-GTPgammaS bind...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
St Louis College of Pharmacy and Washington University

Curated by ChEMBL
LigandPNGBDBM83396(ethyl 1-[(4-acetamidophenyl)methyl]-4-(2-phenyleth...)
Affinity DataEC50:  125nMAssay Description:Agonist activity at EA-fragment beta-arrestin-tagged human MOR expressed in human U2OS cell membranes assessed as stimulation of [35S]-GTPgammaS bind...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
St Louis College of Pharmacy and Washington University

Curated by ChEMBL
LigandPNGBDBM50000507(Tyr-D-Ala-Phe-Glu-Val-Val-GlyNH2 | 4-(2-{2-[2-Amin...)
Affinity DataEC50:  1.94E+3nMAssay Description:Agonist activity at EA-fragment beta-arrestin-tagged human MOR expressed in human U2OS cell membranes assessed as stimulation of [35S]-GTPgammaS bind...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
St Louis College of Pharmacy and Washington University

Curated by ChEMBL
LigandPNGBDBM50554762(CHEMBL4760974)
Affinity DataEC50:  502nMAssay Description:Agonist activity at EA-fragment beta-arrestin-tagged human MOR expressed in human U2OS cell membranes assessed as stimulation of [35S]-GTPgammaS bind...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
St Louis College of Pharmacy and Washington University

Curated by ChEMBL
LigandPNGBDBM50554763(CHEMBL4758061)
Affinity DataEC50:  83nMAssay Description:Agonist activity at EA-fragment beta-arrestin-tagged human MOR expressed in human U2OS cell membranes assessed as stimulation of [35S]-GTPgammaS bind...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
St Louis College of Pharmacy and Washington University

Curated by ChEMBL
LigandPNGBDBM50554764(CHEMBL4761310)
Affinity DataEC50:  110nMAssay Description:Agonist activity at EA-fragment beta-arrestin-tagged human MOR expressed in human U2OS cell membranes assessed as stimulation of [35S]-GTPgammaS bind...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
St Louis College of Pharmacy and Washington University

Curated by ChEMBL
LigandPNGBDBM50554765(CHEMBL4781906)
Affinity DataEC50:  205nMAssay Description:Agonist activity at EA-fragment beta-arrestin-tagged human MOR expressed in human U2OS cell membranes assessed as stimulation of [35S]-GTPgammaS bind...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
St Louis College of Pharmacy and Washington University

Curated by ChEMBL
LigandPNGBDBM50554766(CHEMBL4795492)
Affinity DataEC50:  0.400nMAssay Description:Agonist activity at EA-fragment beta-arrestin-tagged human MOR expressed in human U2OS cell membranes assessed as stimulation of [35S]-GTPgammaS bind...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
St Louis College of Pharmacy and Washington University

Curated by ChEMBL
LigandPNGBDBM50554767(CHEMBL4776176)
Affinity DataEC50:  144nMAssay Description:Agonist activity at EA-fragment beta-arrestin-tagged human MOR expressed in human U2OS cell membranes assessed as stimulation of [35S]-GTPgammaS bind...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
St Louis College of Pharmacy and Washington University

Curated by ChEMBL
LigandPNGBDBM50554768(CHEMBL4783765)
Affinity DataEC50:  85nMAssay Description:Agonist activity at EA-fragment beta-arrestin-tagged human MOR expressed in human U2OS cell membranes assessed as stimulation of [35S]-GTPgammaS bind...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
St Louis College of Pharmacy and Washington University

Curated by ChEMBL
LigandPNGBDBM50554769(CHEMBL4788377)
Affinity DataEC50:  32nMAssay Description:Agonist activity at EA-fragment beta-arrestin-tagged human MOR expressed in human U2OS cell membranes assessed as stimulation of [35S]-GTPgammaS bind...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
St Louis College of Pharmacy and Washington University

Curated by ChEMBL
LigandPNGBDBM50554770(CHEMBL4783653)
Affinity DataEC50:  163nMAssay Description:Agonist activity at EA-fragment beta-arrestin-tagged human MOR expressed in human U2OS cell membranes assessed as stimulation of [35S]-GTPgammaS bind...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
St Louis College of Pharmacy and Washington University

Curated by ChEMBL
LigandPNGBDBM21015([tyrosyl-3,5-3H(N)]-D-Ala2-Mephe4-glyol5-enkephali...)
Affinity DataEC50:  27nMAssay Description:Agonist activity at EA-fragment beta-arrestin-tagged human MOR expressed in human U2OS cell membranes assessed as stimulation of [35S]-GTPgammaS bind...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
St Louis College of Pharmacy and Washington University

Curated by ChEMBL
LigandPNGBDBM50554772(CHEMBL4793926)
Affinity DataEC50:  264nMAssay Description:Agonist activity at EA-fragment beta-arrestin-tagged human MOR expressed in human U2OS cell membranes assessed as stimulation of [35S]-GTPgammaS bind...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
St Louis College of Pharmacy and Washington University

Curated by ChEMBL
LigandPNGBDBM50554773(CHEMBL4779684)
Affinity DataEC50:  191nMAssay Description:Agonist activity at EA-fragment beta-arrestin-tagged human MOR expressed in human U2OS cell membranes assessed as stimulation of [35S]-GTPgammaS bind...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
St Louis College of Pharmacy and Washington University

Curated by ChEMBL
LigandPNGBDBM50554774(CHEMBL4755700)
Affinity DataEC50:  380nMAssay Description:Agonist activity at EA-fragment beta-arrestin-tagged human MOR expressed in human U2OS cell membranes assessed as stimulation of [35S]-GTPgammaS bind...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
St Louis College of Pharmacy and Washington University

Curated by ChEMBL
LigandPNGBDBM50554775(CHEMBL4784650)
Affinity DataEC50:  129nMAssay Description:Agonist activity at EA-fragment beta-arrestin-tagged human MOR expressed in human U2OS cell membranes assessed as stimulation of [35S]-GTPgammaS bind...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
St Louis College of Pharmacy and Washington University

Curated by ChEMBL
LigandPNGBDBM50554776(CHEMBL4751847)
Affinity DataEC50:  16nMAssay Description:Agonist activity at EA-fragment beta-arrestin-tagged human MOR expressed in human U2OS cell membranes assessed as stimulation of [35S]-GTPgammaS bind...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
St Louis College of Pharmacy and Washington University

Curated by ChEMBL
LigandPNGBDBM50554777(CHEMBL4751491)
Affinity DataEC50:  4.33E+3nMAssay Description:Agonist activity at EA-fragment beta-arrestin-tagged human MOR expressed in human U2OS cell membranes assessed as stimulation of [35S]-GTPgammaS bind...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
St Louis College of Pharmacy and Washington University

Curated by ChEMBL
LigandPNGBDBM50554778(CHEMBL4740220)
Affinity DataEC50:  1.58E+3nMAssay Description:Agonist activity at EA-fragment beta-arrestin-tagged human MOR expressed in human U2OS cell membranes assessed as stimulation of [35S]-GTPgammaS bind...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetDelta-type/Mu-type opioid receptor(Mouse)
St Louis College of Pharmacy and Washington University

Curated by ChEMBL
LigandPNGBDBM21015([tyrosyl-3,5-3H(N)]-D-Ala2-Mephe4-glyol5-enkephali...)
Affinity DataEC50:  2.70nMAssay Description:Agonist activity at MOR/DOR in wild-type C57BL6 mouse spinal cord membranes assessed as stimulation of [35S]-GTPgammaS binding measured after 60 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetDelta-type/Mu-type opioid receptor(Mouse)
St Louis College of Pharmacy and Washington University

Curated by ChEMBL
LigandPNGBDBM21015([tyrosyl-3,5-3H(N)]-D-Ala2-Mephe4-glyol5-enkephali...)
Affinity DataEC50:  2.70nMAssay Description:Agonist activity at MOR/DOR in wild-type C57BL6 mouse spinal cord membranes assessed as stimulation of [35S]-GTPgammaS binding measured after 60 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetDelta-type/Mu-type opioid receptor(Mouse)
St Louis College of Pharmacy and Washington University

Curated by ChEMBL
LigandPNGBDBM50000507(Tyr-D-Ala-Phe-Glu-Val-Val-GlyNH2 | 4-(2-{2-[2-Amin...)
Affinity DataEC50:  1.80nMAssay Description:Agonist activity at MOR/DOR in wild-type C57BL6 mouse spinal cord membranes assessed as stimulation of [35S]-GTPgammaS binding measured after 60 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed