Compile Data Set for Download or QSAR
Report error Found 90 Enz. Inhib. hit(s) with all data for entry = 50011585
Target5-hydroxytryptamine receptor 7(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50548816(CHEMBL4753511)
Affinity DataIC50: 100nMAssay Description:Inverse agonist activity at 5-HT7 receptor (unknown origin) by cAMP functional assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50548821(CHEMBL4784845)
Affinity DataKi:  1nMAssay Description:Displacement of [3H]-ketanserin from human 5-HT2B receptor by competitive radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50548831(CHEMBL4752099)
Affinity DataKi:  1nMAssay Description:Displacement of [3H]-ketanserin from human 5-HT2B receptor by competitive radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50548822(CHEMBL4746737)
Affinity DataKi:  1nMAssay Description:Displacement of [3H]-ketanserin from human 5-HT2A receptor by competitive radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50548821(CHEMBL4784845)
Affinity DataKi:  1nMAssay Description:Displacement of [3H]-ketanserin from human 5-HT2A receptor by competitive radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50548818(CHEMBL4782005)
Affinity DataKi:  1nMAssay Description:Displacement of [3H]-ketanserin from human 5-HT2A receptor by competitive radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50548819(CHEMBL4791646)
Affinity DataKi:  2nMAssay Description:Displacement of [3H]-ketanserin from human 5-HT2A receptor by competitive radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50548822(CHEMBL4746737)
Affinity DataKi:  2nMAssay Description:Displacement of [3H]-ketanserin from human 5-HT2B receptor by competitive radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50548817(CHEMBL4789085)
Affinity DataKi:  3nMAssay Description:Displacement of [3H]-ketanserin from human 5-HT2A receptor by competitive radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50548824(CHEMBL4788327)
Affinity DataKi:  3nMAssay Description:Displacement of [3H]-ketanserin from human 5-HT2B receptor by competitive radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50548831(CHEMBL4752099)
Affinity DataKi:  3nMAssay Description:Displacement of [3H]-ketanserin from human 5-HT2A receptor by competitive radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50548824(CHEMBL4788327)
Affinity DataKi:  3nMAssay Description:Displacement of [3H]-ketanserin from human 5-HT2A receptor by competitive radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rat)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50548822(CHEMBL4746737)
Affinity DataKi:  4nMAssay Description:Displacement of [3H]risperidone from alpha1 adrenergic receptor in rat cortex membrane incubated for 60 mins by competitive radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50548818(CHEMBL4782005)
Affinity DataKi:  4nMAssay Description:Displacement of [3H]-ketanserin from human 5-HT2B receptor by competitive radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50548820(CHEMBL4743582)
Affinity DataKi:  5nMAssay Description:Displacement of [3H]-ketanserin from human 5-HT2A receptor by competitive radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50548819(CHEMBL4791646)
Affinity DataKi:  5nMAssay Description:Displacement of [3H]-ketanserin from human 5-HT2B receptor by competitive radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Rat)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50458523(JNJ-18038683)
Affinity DataKi:  6nMAssay Description:Displacement of [3H]-CT from rat 5-HT7 receptor expressed in HEK293 cells by competitive radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50548827(CHEMBL4762886)
Affinity DataKi:  6nMAssay Description:Displacement of [3H]-ketanserin from human 5-HT2A receptor by competitive radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Rat)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50548822(CHEMBL4746737)
Affinity DataKi:  6nMAssay Description:Displacement of [3H]-CT from rat 5-HT7 receptor expressed in HEK293 cells by competitive radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Rat)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50548816(CHEMBL4753511)
Affinity DataKi:  7.90nMAssay Description:Displacement of [3H]-CT from rat 5-HT7 receptor expressed in HEK293 cells by competitive radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50548816(CHEMBL4753511)
Affinity DataKi:  7.90nMAssay Description:Displacement of [3H]-ketanserin from human 5-HT2A receptor by competitive radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Rat)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50548816(CHEMBL4753511)
Affinity DataKi:  8nMAssay Description:Displacement of [3H]-CT from rat 5-HT7 receptor expressed in HEK293 cells by competitive radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50548816(CHEMBL4753511)
Affinity DataKi:  8nMAssay Description:Displacement of [3H]-ketanserin from human 5-HT2A receptor by competitive radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Rat)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50548821(CHEMBL4784845)
Affinity DataKi:  9nMAssay Description:Displacement of [3H]-CT from rat 5-HT7 receptor expressed in HEK293 cells by competitive radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50548822(CHEMBL4746737)
Affinity DataKi:  12nMAssay Description:Displacement of [3H]-ketanserin from human 5-HT2C receptor by competitive radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50548820(CHEMBL4743582)
Affinity DataKi:  12nMAssay Description:Displacement of [3H]-ketanserin from human 5-HT2B receptor by competitive radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Rat)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50548819(CHEMBL4791646)
Affinity DataKi:  15nMAssay Description:Displacement of [3H]-CT from rat 5-HT7 receptor expressed in HEK293 cells by competitive radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50548828(CHEMBL4745055)
Affinity DataKi:  15nMAssay Description:Displacement of [3H]-ketanserin from human 5-HT2A receptor by competitive radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50548823(CHEMBL4750414)
Affinity DataKi:  15nMAssay Description:Displacement of [3H]-ketanserin from human 5-HT2B receptor by competitive radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rat)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50548817(CHEMBL4789085)
Affinity DataKi:  16nMAssay Description:Displacement of [3H]risperidone from alpha1 adrenergic receptor in rat cortex membrane incubated for 60 mins by competitive radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Rat)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50548831(CHEMBL4752099)
Affinity DataKi:  18nMAssay Description:Displacement of [3H]-CT from rat 5-HT7 receptor expressed in HEK293 cells by competitive radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50548821(CHEMBL4784845)
Affinity DataKi:  18nMAssay Description:Displacement of [3H]-ketanserin from human 5-HT2C receptor by competitive radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50548832(CHEMBL4784424)
Affinity DataKi:  19nMAssay Description:Displacement of [3H]-ketanserin from human 5-HT2A receptor by competitive radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50548826(CHEMBL4788223)
Affinity DataKi:  19nMAssay Description:Displacement of [3H]-ketanserin from human 5-HT2B receptor by competitive radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Rat)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50548825(CHEMBL4785470)
Affinity DataKi:  20nMAssay Description:Displacement of [3H]-CT from rat 5-HT7 receptor expressed in HEK293 cells by competitive radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50548827(CHEMBL4762886)
Affinity DataKi:  20nMAssay Description:Displacement of [3H]-ketanserin from human 5-HT2B receptor by competitive radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50548830(CHEMBL4760784)
Affinity DataKi:  20nMAssay Description:Displacement of [3H]-ketanserin from human 5-HT2B receptor by competitive radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rat)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50548821(CHEMBL4784845)
Affinity DataKi:  20nMAssay Description:Displacement of [3H]risperidone from alpha1 adrenergic receptor in rat cortex membrane incubated for 60 mins by competitive radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50548825(CHEMBL4785470)
Affinity DataKi:  20nMAssay Description:Displacement of [3H]-ketanserin from human 5-HT2B receptor by competitive radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50548817(CHEMBL4789085)
Affinity DataKi:  24nMAssay Description:Displacement of [3H]-ketanserin from human 5-HT2B receptor by competitive radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50548826(CHEMBL4788223)
Affinity DataKi:  24nMAssay Description:Displacement of [3H]-ketanserin from human 5-HT2A receptor by competitive radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50548816(CHEMBL4753511)
Affinity DataKi:  25nMAssay Description:Displacement of [3H]-ketanserin from human 5-HT2B receptor by competitive radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50548816(CHEMBL4753511)
Affinity DataKi:  25.1nMAssay Description:Displacement of [3H]-ketanserin from human 5-HT2B receptor by competitive radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Rat)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50548826(CHEMBL4788223)
Affinity DataKi:  28nMAssay Description:Displacement of [3H]-CT from rat 5-HT7 receptor expressed in HEK293 cells by competitive radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50548825(CHEMBL4785470)
Affinity DataKi:  30nMAssay Description:Displacement of [3H]-ketanserin from human 5-HT2A receptor by competitive radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Rat)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50548832(CHEMBL4784424)
Affinity DataKi:  30nMAssay Description:Displacement of [3H]-CT from rat 5-HT7 receptor expressed in HEK293 cells by competitive radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50548825(CHEMBL4785470)
Affinity DataKi:  30nMAssay Description:Displacement of [3H]-ketanserin from human 5-HT2C receptor by competitive radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50548829(CHEMBL4764808)
Affinity DataKi:  31nMAssay Description:Displacement of [3H]-ketanserin from human 5-HT2B receptor by competitive radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50548829(CHEMBL4764808)
Affinity DataKi:  39nMAssay Description:Displacement of [3H]-ketanserin from human 5-HT2A receptor by competitive radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50548830(CHEMBL4760784)
Affinity DataKi:  40nMAssay Description:Displacement of [3H]-ketanserin from human 5-HT2A receptor by competitive radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
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