Compile Data Set for Download or QSAR
Report error Found 29 Enz. Inhib. hit(s) with all data for entry = 50011595
TargetProtein O-GlcNAcase(Human)
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50549046(CHEMBL4741417)
Affinity DataIC50: 17nMAssay Description:Inhibition of OGA in HEK293 cells induced with human Tau P30IL mutant assessed as increase in O-GlcNAcylated protein levels measured after 6 hrs by H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetProtein O-GlcNAcase(Human)
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50549046(CHEMBL4741417)
Affinity DataIC50: 17nMAssay Description:Inhibition of OGA in HEK293 cells induced with human Tau P30IL mutant assessed as increase in O-GlcNAcylated protein levels measured after 6 hrs by H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetProtein O-GlcNAcase(Human)
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50549046(CHEMBL4741417)
Affinity DataIC50: 39nMAssay Description:Inhibition of OGA in HEK293 cells induced with human Tau P30IL mutant assessed as increase in O-GlcNAcylated protein levels measured after 6 hrs by H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetProtein O-GlcNAcase(Human)
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50549055(CHEMBL4792934)
Affinity DataIC50: 46nMAssay Description:Inhibition of OGA in HEK293 cells induced with human Tau P30IL mutant assessed as increase in O-GlcNAcylated protein levels measured after 6 hrs by H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetProtein O-GlcNAcase(Human)
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50549057(CHEMBL4780877)
Affinity DataIC50: 56nMAssay Description:Inhibition of OGA in HEK293 cells induced with human Tau P30IL mutant assessed as increase in O-GlcNAcylated protein levels measured after 6 hrs by H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetProtein O-GlcNAcase(Human)
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50508749(CHEMBL4546591)
Affinity DataIC50: 141nMAssay Description:Inhibition of OGA in HEK293 cells induced with human Tau P30IL mutant assessed as increase in O-GlcNAcylated protein levels measured after 6 hrs by H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetProtein O-GlcNAcase(Human)
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50508753(CHEMBL4580690)
Affinity DataIC50: 170nMAssay Description:Inhibition of OGA in HEK293 cells induced with human Tau P30IL mutant assessed as increase in O-GlcNAcylated protein levels measured after 6 hrs by H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetProtein O-GlcNAcase(Human)
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50549052(CHEMBL4751010)
Affinity DataIC50: 182nMAssay Description:Inhibition of OGA in HEK293 cells induced with human Tau P30IL mutant assessed as increase in O-GlcNAcylated protein levels measured after 6 hrs by H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetProtein O-GlcNAcase(Human)
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50549054(CHEMBL4796019)
Affinity DataIC50: 214nMAssay Description:Inhibition of OGA in HEK293 cells induced with human Tau P30IL mutant assessed as increase in O-GlcNAcylated protein levels measured after 6 hrs by H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetProtein O-GlcNAcase(Human)
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50549049(CHEMBL4791287)
Affinity DataIC50: 240nMAssay Description:Inhibition of OGA in HEK293 cells induced with human Tau P30IL mutant assessed as increase in O-GlcNAcylated protein levels measured after 6 hrs by H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetProtein O-GlcNAcase(Human)
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50549050(CHEMBL4757711)
Affinity DataIC50: 295nMAssay Description:Inhibition of OGA in HEK293 cells induced with human Tau P30IL mutant assessed as increase in O-GlcNAcylated protein levels measured after 6 hrs by H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetProtein O-GlcNAcase(Human)
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50549056(CHEMBL4747641)
Affinity DataIC50: 380nMAssay Description:Inhibition of OGA in HEK293 cells induced with human Tau P30IL mutant assessed as increase in O-GlcNAcylated protein levels measured after 6 hrs by H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetProtein O-GlcNAcase(Human)
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50549058(CHEMBL4754121)
Affinity DataIC50: 437nMAssay Description:Inhibition of OGA in HEK293 cells induced with human Tau P30IL mutant assessed as increase in O-GlcNAcylated protein levels measured after 6 hrs by H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetProtein O-GlcNAcase(Human)
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50549047(CHEMBL4787801)
Affinity DataIC50: 501nMAssay Description:Inhibition of OGA in HEK293 cells induced with human Tau P30IL mutant assessed as increase in O-GlcNAcylated protein levels measured after 6 hrs by H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetProtein O-GlcNAcase(Human)
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50549051(CHEMBL4742799)
Affinity DataIC50: 537nMAssay Description:Inhibition of OGA in HEK293 cells induced with human Tau P30IL mutant assessed as increase in O-GlcNAcylated protein levels measured after 6 hrs by H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetProtein O-GlcNAcase(Human)
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50549048(CHEMBL4748742)
Affinity DataIC50: 537nMAssay Description:Inhibition of OGA in HEK293 cells induced with human Tau P30IL mutant assessed as increase in O-GlcNAcylated protein levels measured after 6 hrs by H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetProtein O-GlcNAcase(Human)
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50549064(CHEMBL4778493)
Affinity DataIC50: 575nMAssay Description:Inhibition of OGA in HEK293 cells induced with human Tau P30IL mutant assessed as increase in O-GlcNAcylated protein levels measured after 6 hrs by H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetProtein O-GlcNAcase(Human)
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50549053(CHEMBL4799707)
Affinity DataIC50: 603nMAssay Description:Inhibition of OGA in HEK293 cells induced with human Tau P30IL mutant assessed as increase in O-GlcNAcylated protein levels measured after 6 hrs by H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetProtein O-GlcNAcase(Human)
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50549063(CHEMBL4741594)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of OGA in HEK293 cells induced with human Tau P30IL mutant assessed as increase in O-GlcNAcylated protein levels measured after 6 hrs by H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetProtein O-GlcNAcase(Human)
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50549061(CHEMBL4741796)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of OGA in HEK293 cells induced with human Tau P30IL mutant assessed as increase in O-GlcNAcylated protein levels measured after 6 hrs by H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetProtein O-GlcNAcase(Human)
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50549060(CHEMBL4763548)
Affinity DataIC50: 9.33E+3nMAssay Description:Inhibition of OGA in HEK293 cells induced with human Tau P30IL mutant assessed as increase in O-GlcNAcylated protein levels measured after 6 hrs by H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetProtein O-GlcNAcase(Human)
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50549059(CHEMBL4742928)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of OGA in HEK293 cells induced with human Tau P30IL mutant assessed as increase in O-GlcNAcylated protein levels measured after 6 hrs by H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50549046(CHEMBL4741417)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP1A2 in human liver microsomes using isoform-specific probe substrates by LC/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50549046(CHEMBL4741417)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2C19 in human liver microsomes using isoform-specific probe substrates by LC/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50549046(CHEMBL4741417)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2C9 in human liver microsomes using isoform-specific probe substrates by LC/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50549046(CHEMBL4741417)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2D6 in human liver microsomes using isoform-specific probe substrates by LC/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50549046(CHEMBL4741417)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using isoform-specific probe substrates by LC/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetProtein O-GlcNAcase(Human)
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50549065(CHEMBL4762217)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of OGA in HEK293 cells induced with human Tau P30IL mutant assessed as increase in O-GlcNAcylated protein levels measured after 6 hrs by H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetProtein O-GlcNAcase(Human)
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50549062(CHEMBL4797556)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of OGA in HEK293 cells induced with human Tau P30IL mutant assessed as increase in O-GlcNAcylated protein levels measured after 6 hrs by H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed