Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 50012946
TargetPresenilin-1(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50561735(CHEMBL4793879 | US12195470, Example 8)
Affinity DataIC50: 6.30nMAssay Description:Inhibition of human gamma secretase assessed as reduction in Abeta42 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50561738(CHEMBL4793969 | US12195470, Example 49)
Affinity DataIC50: 6.60nMAssay Description:Inhibition of human gamma secretase assessed as reduction in Abeta42 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50561734(CHEMBL4782495 | US12195470, Example 3)
Affinity DataIC50: 8.10nMAssay Description:Inhibition of human gamma secretase assessed as reduction in Abeta42 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50561739(CHEMBL4741478 | US12195470, Example 55)
Affinity DataIC50: 8.10nMAssay Description:Inhibition of human gamma secretase assessed as reduction in Abeta42 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50561736(CHEMBL4750933 | US12195470, Example 41)
Affinity DataIC50: 9.90nMAssay Description:Inhibition of human gamma secretase assessed as reduction in Abeta42 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50561737(CHEMBL4788632 | US12195470, Example 45)
Affinity DataIC50: 10nMAssay Description:Inhibition of human gamma secretase assessed as reduction in Abeta42 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed