Compile Data Set for Download or QSAR
Report error Found 85 Enz. Inhib. hit(s) with all data for entry = 50013690
TargetKappa-type opioid receptor(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50000296(CHEMBL441765 | CHEMBL482811 | U-50488H | US1149237...)
Affinity DataKi:  0.0940nMAssay Description:Displacement of [3H]-U69593 from human kappa opioid receptor expressed in U2OS cells by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50000296(CHEMBL441765 | CHEMBL482811 | U-50488H | US1149237...)
Affinity DataKi:  0.100nMAssay Description:Displacement of [3H]-U69593 from human kappa opioid receptor expressed in U2OS cells by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM21015([tyrosyl-3,5-3H(N)]-D-Ala2-Mephe4-glyol5-enkephali...)
Affinity DataKi:  0.350nMAssay Description:Displacement of [3H]-DAMGO from human mu opioid receptor expressed in CHO-K1 cells by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM21015([tyrosyl-3,5-3H(N)]-D-Ala2-Mephe4-glyol5-enkephali...)
Affinity DataKi:  0.350nMAssay Description:Displacement of [3H]-DAMGO from human mu opioid receptor expressed in CHO-K1 cells by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50001465(2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionyl...)
Affinity DataKi:  1.20nMAssay Description:Displacement of [3H]-DPDPE from human delta opioid receptor expressed in CHO-K1 cells by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50001465(2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionyl...)
Affinity DataKi:  1.30nMAssay Description:Displacement of [3H]-DPDPE from human delta opioid receptor expressed in CHO-K1 cells by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Mouse)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50001465(2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionyl...)
Affinity DataIC50: 1.30nMAssay Description:Agonist activity at mouse FLAG-tagged delta opioid receptor expressed in HEK293 cells assessed as inhibition of forskolin-induced cAMP production pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Mouse)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50001465(2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionyl...)
Affinity DataIC50: 1.40nMAssay Description:Agonist activity at mouse FLAG-tagged delta opioid receptor expressed in HEK293 cells assessed as inhibition of forskolin-induced cAMP production pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Mouse)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50000296(CHEMBL441765 | CHEMBL482811 | U-50488H | US1149237...)
Affinity DataIC50: 1.5nMAssay Description:Agonist activity at mouse FLAG-tagged kappa opioid receptor expressed in HEK293 cells assessed as inhibition of forskolin-induced cAMP production pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Mouse)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50000296(CHEMBL441765 | CHEMBL482811 | U-50488H | US1149237...)
Affinity DataIC50: 1.5nMAssay Description:Agonist activity at mouse FLAG-tagged kappa opioid receptor expressed in HEK293 cells assessed as inhibition of forskolin-induced cAMP production pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetMu-type opioid receptor(Mouse)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM21015([tyrosyl-3,5-3H(N)]-D-Ala2-Mephe4-glyol5-enkephali...)
Affinity DataIC50: 6.30nMAssay Description:Agonist activity at mouse HA-tagged mu opioid receptor expressed in HEK293 cells assessed as inhibition of forskolin-induced cAMP production preincub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetMu-type opioid receptor(Mouse)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM21015([tyrosyl-3,5-3H(N)]-D-Ala2-Mephe4-glyol5-enkephali...)
Affinity DataIC50: 6.60nMAssay Description:Agonist activity at mouse HA-tagged mu opioid receptor expressed in HEK293 cells assessed as inhibition of forskolin-induced cAMP production preincub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50001465(2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionyl...)
Affinity DataEC50:  13nMAssay Description:Agonist activity at human delta opioid receptor expressed in CHO-K1 cells assessed as beta-arrestin2 recruitment incubated for 90 mins by PathHunter ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50000296(CHEMBL441765 | CHEMBL482811 | U-50488H | US1149237...)
Affinity DataEC50:  32nMAssay Description:Agonist activity at human kappa opioid receptor expressed in U2OS cells assessed as beta-arrestin2 recruitment incubated for 90 mins by PathHunter as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Mouse)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50568638(CHEMBL4871880)
Affinity DataIC50: 73nMAssay Description:Agonist activity at mouse FLAG-tagged kappa opioid receptor expressed in HEK293 cells assessed as inhibition of forskolin-induced cAMP production pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50292340(CHEMBL508955 | AKUAMMICINE)
Affinity DataKi:  89nMAssay Description:Displacement of [3H]-U69593 from human kappa opioid receptor expressed in U2OS cells by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50292340(CHEMBL508955 | AKUAMMICINE)
Affinity DataKi:  89nMAssay Description:Displacement of [3H]-U69593 from human kappa opioid receptor expressed in U2OS cells by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM21015([tyrosyl-3,5-3H(N)]-D-Ala2-Mephe4-glyol5-enkephali...)
Affinity DataEC50:  200nMAssay Description:Agonist activity at human mu opioid receptor expressed in CHO-K1 assessed as beta-arrestin2 recruitment incubated for 90 mins by PathHunter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Mouse)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50292340(CHEMBL508955 | AKUAMMICINE)
Affinity DataIC50: 240nMAssay Description:Agonist activity at mouse FLAG-tagged kappa opioid receptor expressed in HEK293 cells assessed as inhibition of forskolin-induced cAMP production pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Mouse)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50292340(CHEMBL508955 | AKUAMMICINE)
Affinity DataIC50: 251nMAssay Description:Agonist activity at mouse FLAG-tagged kappa opioid receptor expressed in HEK293 cells assessed as inhibition of forskolin-induced cAMP production pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50568638(CHEMBL4871880)
Affinity DataKi:  300nMAssay Description:Displacement of [3H]-DAMGO from human mu opioid receptor expressed in CHO-K1 cells by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50568638(CHEMBL4871880)
Affinity DataKi:  316nMAssay Description:Displacement of [3H]-DAMGO from human mu opioid receptor expressed in CHO-K1 cells by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50568642(CHEMBL4856018)
Affinity DataKi:  316nMAssay Description:Displacement of [3H]-DAMGO from human mu opioid receptor expressed in CHO-K1 cells by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50568642(CHEMBL4856018)
Affinity DataKi:  320nMAssay Description:Displacement of [3H]-DAMGO from human mu opioid receptor expressed in CHO-K1 cells by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50568639(CHEMBL4846243)
Affinity DataKi:  590nMAssay Description:Displacement of [3H]-DAMGO from human mu opioid receptor expressed in CHO-K1 cells by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50568639(CHEMBL4846243)
Affinity DataKi:  631nMAssay Description:Displacement of [3H]-DAMGO from human mu opioid receptor expressed in CHO-K1 cells by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50568640(CHEMBL4874877)
Affinity DataKi:  1.11E+3nMAssay Description:Displacement of [3H]-U69593 from human kappa opioid receptor expressed in U2OS cells by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50568640(CHEMBL4874877)
Affinity DataKi:  1.11E+3nMAssay Description:Displacement of [3H]-U69593 from human kappa opioid receptor expressed in U2OS cells by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50568638(CHEMBL4871880)
Affinity DataKi:  1.59E+3nMAssay Description:Displacement of [3H]-U69593 from human kappa opioid receptor expressed in U2OS cells by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50568638(CHEMBL4871880)
Affinity DataKi:  1.68E+3nMAssay Description:Displacement of [3H]-U69593 from human kappa opioid receptor expressed in U2OS cells by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Mouse)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50568641(CHEMBL4852987)
Affinity DataIC50: 1.97E+3nMAssay Description:Agonist activity at mouse FLAG-tagged kappa opioid receptor expressed in HEK293 cells assessed as inhibition of forskolin-induced cAMP production pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Mouse)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50568641(CHEMBL4852987)
Affinity DataIC50: 2.00E+3nMAssay Description:Agonist activity at mouse FLAG-tagged kappa opioid receptor expressed in HEK293 cells assessed as inhibition of forskolin-induced cAMP production pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50568639(CHEMBL4846243)
Affinity DataKi:  2.25E+3nMAssay Description:Displacement of [3H]-U69593 from human kappa opioid receptor expressed in U2OS cells by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50568639(CHEMBL4846243)
Affinity DataKi:  2.25E+3nMAssay Description:Displacement of [3H]-U69593 from human kappa opioid receptor expressed in U2OS cells by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50568641(CHEMBL4852987)
Affinity DataKi:  2.38E+3nMAssay Description:Displacement of [3H]-U69593 from human kappa opioid receptor expressed in U2OS cells by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Mouse)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50568640(CHEMBL4874877)
Affinity DataIC50: 2.51E+3nMAssay Description:Agonist activity at mouse FLAG-tagged kappa opioid receptor expressed in HEK293 cells assessed as inhibition of forskolin-induced cAMP production pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetMu-type opioid receptor(Mouse)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50568638(CHEMBL4871880)
Affinity DataIC50: 2.51E+3nMAssay Description:Agonist activity at mouse HA-tagged mu opioid receptor expressed in HEK293 cells assessed as inhibition of forskolin-induced cAMP production preincub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50568641(CHEMBL4852987)
Affinity DataKi:  2.51E+3nMAssay Description:Displacement of [3H]-U69593 from human kappa opioid receptor expressed in U2OS cells by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetMu-type opioid receptor(Mouse)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50568638(CHEMBL4871880)
Affinity DataIC50: 2.60E+3nMAssay Description:Agonist activity at mouse HA-tagged mu opioid receptor expressed in HEK293 cells assessed as inhibition of forskolin-induced cAMP production preincub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Mouse)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50568640(CHEMBL4874877)
Affinity DataIC50: 2.71E+3nMAssay Description:Agonist activity at mouse FLAG-tagged kappa opioid receptor expressed in HEK293 cells assessed as inhibition of forskolin-induced cAMP production pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetMu-type opioid receptor(Mouse)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50568642(CHEMBL4856018)
Affinity DataIC50: 3.14E+3nMAssay Description:Agonist activity at mouse HA-tagged mu opioid receptor expressed in HEK293 cells assessed as inhibition of forskolin-induced cAMP production preincub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetMu-type opioid receptor(Mouse)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50568642(CHEMBL4856018)
Affinity DataIC50: 3.16E+3nMAssay Description:Agonist activity at mouse HA-tagged mu opioid receptor expressed in HEK293 cells assessed as inhibition of forskolin-induced cAMP production preincub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50292340(CHEMBL508955 | AKUAMMICINE)
Affinity DataKi:  3.16E+3nMAssay Description:Displacement of [3H]-DAMGO from human mu opioid receptor expressed in CHO-K1 cells by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50292340(CHEMBL508955 | AKUAMMICINE)
Affinity DataKi:  3.31E+3nMAssay Description:Displacement of [3H]-DAMGO from human mu opioid receptor expressed in CHO-K1 cells by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetMu-type opioid receptor(Mouse)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50568639(CHEMBL4846243)
Affinity DataIC50: 5.01E+3nMAssay Description:Agonist activity at mouse HA-tagged mu opioid receptor expressed in HEK293 cells assessed as inhibition of forskolin-induced cAMP production preincub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetMu-type opioid receptor(Mouse)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50568639(CHEMBL4846243)
Affinity DataIC50: 5.24E+3nMAssay Description:Agonist activity at mouse HA-tagged mu opioid receptor expressed in HEK293 cells assessed as inhibition of forskolin-induced cAMP production preincub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Mouse)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50568639(CHEMBL4846243)
Affinity DataIC50: 6.31E+3nMAssay Description:Agonist activity at mouse FLAG-tagged kappa opioid receptor expressed in HEK293 cells assessed as inhibition of forskolin-induced cAMP production pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Mouse)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50568639(CHEMBL4846243)
Affinity DataIC50: 6.46E+3nMAssay Description:Agonist activity at mouse FLAG-tagged kappa opioid receptor expressed in HEK293 cells assessed as inhibition of forskolin-induced cAMP production pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetMu-type opioid receptor(Mouse)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50292340(CHEMBL508955 | AKUAMMICINE)
Affinity DataIC50: 7.94E+3nMAssay Description:Agonist activity at mouse HA-tagged mu opioid receptor expressed in HEK293 cells assessed as inhibition of forskolin-induced cAMP production preincub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50568639(CHEMBL4846243)
Affinity DataKi:  7.94E+3nMAssay Description:Displacement of [3H]-DPDPE from human delta opioid receptor expressed in CHO-K1 cells by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
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