Report error Found 42 Enz. Inhib. hit(s) with all data for entry = 50015584
Affinity DataEC50: 6.65E+4nMAssay Description:Agonist activity at STING in mouse 293T Cells incubated for 48 hrs by QUANTI-blue assayMore data for this Ligand-Target Pair
Affinity DataKd: 2.64E+4nMAssay Description:Binding affinity to human STING (137 to 379 residues) assessed as dissociation constant by isothermal titration calorimetry assayMore data for this Ligand-Target Pair
Affinity DataKd: 1.60nMAssay Description:Binding affinity to human C-terminal domain STING (139 to 379 residues) assessed as dissociation constant by scanning fluorimetry assayMore data for this Ligand-Target Pair
Affinity DataEC50: 7.45E+3nMAssay Description:Agonist activity at STING in human 293T hSTING-R232 Cells incubated for 48 hrs by QUANTI-blue assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.35E+5nMAssay Description:Agonist activity at STING in human 293T hSTING-R232 Cells incubated for 48 hrs by QUANTI-blue assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.54E+5nMAssay Description:Agonist activity at STING in human 293T hSTING-R232 Cells incubated for 48 hrs by QUANTI-blue assayMore data for this Ligand-Target Pair
Affinity DataEC50: 7.01E+3nMAssay Description:Agonist activity at STING in mouse 293T Cells incubated for 48 hrs by QUANTI-blue assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.02E+4nMAssay Description:Agonist activity at STING in mouse 293T Cells incubated for 48 hrs by QUANTI-blue assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.35E+5nMAssay Description:Agonist activity at STING in mouse 293T Cells incubated for 48 hrs by QUANTI-blue assayMore data for this Ligand-Target Pair
Affinity DataEC50: 7.23E+4nMAssay Description:Agonist activity at STING in mouse 293T Cells incubated for 48 hrs by QUANTI-blue assayMore data for this Ligand-Target Pair
Affinity DataEC50: 7.23E+3nMAssay Description:Agonist activity at STING in human 293T hSTING-R232 Cells incubated for 48 hrs by QUANTI-blue assayMore data for this Ligand-Target Pair
Affinity DataEC50: 3.10E+3nMAssay Description:Agonist activity to C-terminal domain STING (139 to 379 residues) in human PBMC assessed as IFN-beta secretionMore data for this Ligand-Target Pair
Affinity DataEC50: 130nMAssay Description:Agonist activity to C-terminal domain STING (139 to 379 residues) in human PBMC assessed as IFN-beta secretionMore data for this Ligand-Target Pair
Affinity DataEC50: 190nMAssay Description:Agonist activity to C-terminal domain STING HAQ mutant (139 to 379 residues) in human PBMC assessed as IFN-beta secretionMore data for this Ligand-Target Pair
Affinity DataEC50: 186nMAssay Description:Agonist activity at mouse STING assessed as IFN-beta secretionMore data for this Ligand-Target Pair
Affinity DataKd: 5.30E+4nMAssay Description:Binding affinity to human NT-647-labeled C-terminal domain STING R232 mutant (149 to 379residues) expressed in Escherichia coli BL21 (DE3) assessed a...More data for this Ligand-Target Pair
Affinity DataEC50: 42nMAssay Description:Antagonist activity at STING (unknown origin) in L929 cells assessed as IFN-beta RNA level q-RTPCR analysisMore data for this Ligand-Target Pair
Affinity DataKd: 4.20E+4nMAssay Description:Binding affinity to C-terminal domain human STING (139 to 379 residues) assessed as dissociation constant by DSF methodMore data for this Ligand-Target Pair
Affinity DataKd: 1.57E+5nMAssay Description:Binding affinity to C-terminal domain human STING (139 to 379 residues) assessed as dissociation constant by DSF methodMore data for this Ligand-Target Pair
Affinity DataKd: 2.20E+4nMAssay Description:Binding affinity to rat STING assessed as dissociation constant by isothermal titration calorimetry assayMore data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataKd: 7.90E+4nMAssay Description:Binding affinity to STING (unknown origin) assessed as dissociation constant by isothermal titration calorimetry assayMore data for this Ligand-Target Pair
Affinity DataEC50: 19nMAssay Description:Agonist activity at STING in human L929 cells assessed as IFN-beta RNA level measured after 4 hrs by qRT-PCR analysisMore data for this Ligand-Target Pair
Affinity DataEC50: 19nMAssay Description:Agonist activity at STING in human L929 cells assessed as IFN-beta RNA level measured after 4 hrs by qRT-PCR analysisMore data for this Ligand-Target Pair
Affinity DataEC50: 538nMAssay Description:Agonist activity at STING in human L929 cells assessed as IFN-beta RNA level measured after 4 hrs by qRT-PCR analysisMore data for this Ligand-Target Pair
Affinity DataEC50: 51nMAssay Description:Agonist activity at STING (unknown origin) in THP1-Blue ISG cells assessed as type I interferon production levelMore data for this Ligand-Target Pair
Affinity DataKd: 4nMAssay Description:Binding affinity to C-terminal domain human STING (139 to 379 residues) expressed in E. coli assessed as dissociation constant by isothermal titratio...More data for this Ligand-Target Pair
Affinity DataKd: 1.04E+3nMAssay Description:Binding affinity to C-terminal domain human STING (139 to 379 residues) expressed in E. coli assessed as dissociation constant by isothermal titratio...More data for this Ligand-Target Pair
Affinity DataKd: 710nMAssay Description:Binding affinity to mouse STING (154 to 340 residues) assessed as dissociation constant by isothermal titration calorimetry assayMore data for this Ligand-Target Pair
Affinity DataKd: 2.60E+4nMAssay Description:Binding affinity to rat STING assessed as dissociation constant by isothermal titration calorimetry assayMore data for this Ligand-Target Pair
Affinity DataKd: 2.60E+4nMAssay Description:Binding affinity to rat STING assessed as dissociation constant by isothermal titration calorimetry assayMore data for this Ligand-Target Pair
Affinity DataKd: 8.34E+4nMAssay Description:Binding affinity to mouse STING assessed as dissociation constant by canning fluorimetry based thermal shift assayMore data for this Ligand-Target Pair
Affinity DataKd: 5.22E+5nMAssay Description:Binding affinity to mouse STING assessed as dissociation constant by canning fluorimetry based thermal shift assayMore data for this Ligand-Target Pair
Affinity DataKd: 1.49E+5nMAssay Description:Binding affinity to mouse STING assessed as dissociation constant by canning fluorimetry based thermal shift assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.53E+5nMAssay Description:Agonist activity at STING (unknown origin) in murine cellsMore data for this Ligand-Target Pair
Affinity DataKd: 1.21E+3nMAssay Description:Binding affinity to C-terminal domain human STING (139 to 379 residues) expressed in E. coli assessed as dissociation constant by isothermal titratio...More data for this Ligand-Target Pair
Affinity DataKd: 0.200nMAssay Description:Binding affinity to human STING (137 to 379 residues) assessed as dissociation constant by isothermal titration calorimetry assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4.60nMAssay Description:Agonist activity at human STING incubated for 3 hrs by fluorescence based analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Agonist activity to C-terminal domain human STING (139 to 379 residues)More data for this Ligand-Target Pair
Affinity DataIC50: 1.92E+3nMAssay Description:Agonist activity at human STING incubated for 3 hrs by fluorescence based analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 3.42E+3nMAssay Description:Antagonist activity at STING in MEF cells by Flowcytometry assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.08E+4nMAssay Description:Antagonist activity at STING in human IMR-90 cells by Flowcytometry assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+4nMAssay Description:Agonist activity to C-terminal domain human STING (139 to 379 residues)More data for this Ligand-Target Pair
