Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 50013448
TargetVitamin D3 receptor(Human)
Ochanomizu University

Curated by ChEMBL
LigandPNGBDBM50565949(CHEMBL4794075)
Affinity DataEC50:  0.0140nMAssay Description:Agonist activity at human VDR expressed in HEK293 cells expressing mouse osteopontin VDRE assessed as induction of receptor transactivation incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetVitamin D3 receptor(Bovine)
Ochanomizu University

Curated by ChEMBL
LigandPNGBDBM50200182((1S,3R,5Z,7E)-9,10-secocholesta-5,7,10(19)-triene-...)
Affinity DataIC50: 0.0480nMAssay Description:Displacement of [3H]-1-alpha,25-(OH)2D3 from bovine thymus VDR incubated for 18 hrs by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetVitamin D3 receptor(Human)
Ochanomizu University

Curated by ChEMBL
LigandPNGBDBM50565950(CHEMBL4776651)
Affinity DataEC50:  0.150nMAssay Description:Agonist activity at human VDR expressed in HEK293 cells expressing mouse osteopontin VDRE assessed as induction of receptor transactivation incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetVitamin D3 receptor(Human)
Ochanomizu University

Curated by ChEMBL
LigandPNGBDBM50565949(CHEMBL4794075)
Affinity DataEC50:  0.240nMAssay Description:Agonist activity at human VDR expressed in African green monkey COS7 cells expressing mouse osteopontin VDRE assessed as induction of receptor transa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetVitamin D3 receptor(Human)
Ochanomizu University

Curated by ChEMBL
LigandPNGBDBM50565950(CHEMBL4776651)
Affinity DataEC50:  0.530nMAssay Description:Agonist activity at VDR in human HL-60 cells assessed as induction of cell differentiation of promyelocytes to monocytes after 4 days by NBT reductio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetVitamin D3 receptor(Human)
Ochanomizu University

Curated by ChEMBL
LigandPNGBDBM50565950(CHEMBL4776651)
Affinity DataEC50:  1nMAssay Description:Agonist activity at human VDR expressed in African green monkey COS7 cells expressing mouse osteopontin VDRE assessed as induction of receptor transa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetVitamin D3 receptor(Human)
Ochanomizu University

Curated by ChEMBL
LigandPNGBDBM50200182((1S,3R,5Z,7E)-9,10-secocholesta-5,7,10(19)-triene-...)
Affinity DataEC50:  1.60nMAssay Description:Agonist activity at VDR in human HL-60 cells assessed as induction of cell differentiation of promyelocytes to monocytes after 4 days by NBT reductio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetVitamin D3 receptor(Bovine)
Ochanomizu University

Curated by ChEMBL
LigandPNGBDBM50565950(CHEMBL4776651)
Affinity DataIC50: 2.10nMAssay Description:Displacement of [3H]-1-alpha,25-(OH)2D3 from bovine thymus VDR incubated for 18 hrs by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetVitamin D3 receptor(Human)
Ochanomizu University

Curated by ChEMBL
LigandPNGBDBM50200182((1S,3R,5Z,7E)-9,10-secocholesta-5,7,10(19)-triene-...)
Affinity DataEC50:  4.90nMAssay Description:Agonist activity at human VDR expressed in HEK293 cells expressing mouse osteopontin VDRE assessed as induction of receptor transactivation incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetVitamin D3 receptor(Human)
Ochanomizu University

Curated by ChEMBL
LigandPNGBDBM50200182((1S,3R,5Z,7E)-9,10-secocholesta-5,7,10(19)-triene-...)
Affinity DataEC50:  7nMAssay Description:Agonist activity at human VDR expressed in African green monkey COS7 cells expressing mouse osteopontin VDRE assessed as induction of receptor transa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetVitamin D3 receptor(Human)
Ochanomizu University

Curated by ChEMBL
LigandPNGBDBM50565949(CHEMBL4794075)
Affinity DataEC50:  36nMAssay Description:Agonist activity at VDR in human HL-60 cells assessed as induction of cell differentiation of promyelocytes to monocytes after 4 days by NBT reductio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetVitamin D3 receptor(Bovine)
Ochanomizu University

Curated by ChEMBL
LigandPNGBDBM50565949(CHEMBL4794075)
Affinity DataIC50: 67nMAssay Description:Displacement of [3H]-1-alpha,25-(OH)2D3 from bovine thymus VDR incubated for 18 hrs by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed